Intracellular pathogens
Phagosome lysosome Fusion Hijack An Art of Intracellular Pathogens
... Certain pathogens ensure their survival by activating alternate pathways of complement ...other intracellular pathogens through CR decide the fate of phagosome-lysosome ...
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VALIDATE: Exploiting the synergy between complex intracellular pathogens to expedite vaccine research and development for tuberculosis, leishmaniasis, melioidosis and leprosy
... these pathogens which involves basic research vaccine design and vaccine evaluation in preclinical challenge models and clinical trials is inefficient for these complex intracellular pathogens We ...
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Nanomedicine as an emerging approach against intracellular pathogens
... by intracellular pathogens and are a major burden to the global medical ...The pathogens reside within intracellular compartments of the cell, which provide additional barriers to effective ...
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Innate host defense against intracellular pathogens
... in intracellular compartments, resulting in excessive intracellular replication during early pathogenesis and increased extracellular growth of the bacteria during later stages of ...against ...
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Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogens
... an intracellular bacterial pathogen whose capacity to multiply in human mononuclear phagocytes is dependent upon the availability of intracellular ...pneumophila intracellular multiplication in human ...
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Camouflage and interception:How pathogens evade detection by intracellular nucleic acid sensors
... other intracellular pathogens, causing the secretion of type I interferons, cytokines and chemokines from infected ...many pathogens before they are able to establish an infection in the ...some ...
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Host-Apicomplexan Parasite Interactions: Leveraging Biological Discovery into Antiparasitic Drug Development
... obligate intracellular pathogens Plasmodium falciparum and Toxoplasma gondii remodel their host cell to facilitate their intracellular development and progress through their asexual life cycle, a ...
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Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses
... destroy intracellular pathogens ...and intracellular pathogens by de novo formation of double- layer membranes [7]: 2) microautophagy that is used to engulf a part of the cytoplasm by the ...
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Camouflage and interception:How pathogens evade detection by intracellular nucleic acid sensors
... emerging pathogens, and aid in the design of vaccine ...by pathogens to evade recognition are also becoming ...which intracellular pathogens hide from detection or intercept the cell’s ...
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Mycobacteria and Autophagy: Many Questions and Few Answers
... control intracellular Mtb by inducing autophagy, which is an elaborate cellular process to target intracellular pathogens for degradation in infected ...
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From Christian de Duve to Yoshinori Ohsumi : more to autophagy than just dining at home
... of intracellular pathogens, antigen presen- tation and T cell polarisation: however, this critical and complex cellular homeostatic mechanism also controls inflammation, acting to antagonise inflammasome ...
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Host Directed Antimicrobial Drugs with Broad Spectrum Efficacy against Intracellular Bacterial Pathogens
... by intracellular bacteria, namely, by altering host cell functions that support their ...inhibiting intracellular bacterial growth with limited toxicity to host ...(ii) intracellular calcium signals, ...
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Forests and emerging infectious diseases: unleashing the beast within
... These continued environmental changes interacting with human and animal demographics on Earth might reasonably be shown to have a greater immediate impact on current and future zoonotic and vector-borne emerging ...
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Evolution of sibling fungal plant pathogens in relation to host specialization
... The approaches to modeling evolution can be broadly catego- rized into population genetic models and epidemiological models (of which adaptive dynamics is one example). The population genetics approach has been used ...
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Identification of Bacterial Fish Pathogens in Brazil by Direct Colony PCR and 16S rRNA Gene Sequencing
... these pathogens [25], which causes hemorrhagic sep- ticemia, characterized by small superficial lesions, focal hemorrhages, ulcers, abscesses, and abdominal disten- ...
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Estimation of infectious risks in residential populations exposed to airborne pathogens during center pivot irrigation of dairy wastewaters
... from pathogens as determined by the results from this QMRA, which is also supported by risk assessments that considered aerosol generation and transport during land application of ...airborne pathogens ...
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Detection of Zoonotic Pathogens and Characterization of Novel Viruses Carried by Commensal Rattus norvegicus in New York City
... High viral diversity in commensal Norway rats in NYC. De- spite surveying only 133 rats, we identified a wide diversity of viruses from families and genera that contain important human pathogens, including new ...
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The H-Index as a Quantitative Indicator of the Relative Impact of Human Diseases
... However, there are also many advantages to the use of the H- index method. It can be rapidly obtained (one person obtained the 1414 H-indices in two weeks) and has the potential to be automated and repeated regularly. It ...
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Epidemiology of bacterial pathogens associated with infectious diarrhea in Djibouti
... The distribution of bacterial pathogens recovered from patients and controls indicates that most enteric pathogens were isolated at similar frequencies from both diarrheal and control st[r] ...
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Disarming Fungal Pathogens: Bacillus safensis Inhibits Virulence Factor Production and Biofilm Formation by Cryptococcus neoformans and Candida albicans
... ABSTRACT Bacteria interact with each other in nature and often compete for lim- ited nutrient and space resources. However, it is largely unknown whether and how bacteria also interact with human fungal pathogens ...
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