ion channel
Silicon-based ion channel sensor
... The latter point is the reason why silicon was chosen as the substrate over glass [12–14]. While similar approaches use a silicon nitride layer as support [8–10], our process provides electrical isolation using only ...
7
An energetic variational approach to ion channel dynamics
... the channel and the bath. The charge density profiles produced by the channel potential energy of MPNP-C system are presented in the right picture of Figure ...the channel potential energy that forms ...
10
Identification of ion channel genes in the Acyrthosiphon pisum genome
... and ion homeostasis. There are several families of ion channels that have different specificities for the ions trans- ...ported. Ion channels can be activated by voltage-sensing or by ligand binding, ...
14
ROLES OF THE ION CHANNEL NALCN IN NEURONAL EXCITABILITY CONTROL
... via ion channels. The molecular identity of some of the ion channels involved has just begun to be ...the ion channel NALCN provides a major contribution to the neuronal excitability control ...
211
INVERSE PROBLEMS RELATED TO ION CHANNEL SELECTIVITY
... of ion channels and the already known identifica- tion of doping profiles in ...an ion channel, and so this antisymmetry is broken, and uniqueness in the identification becomes more ...
30
Ion channel activity in lobster skeletal muscle membrane
... Ion channel activity in the sarcolemmal membrane of muscle fibers is critical for regulating the excitability, and therefore the contractility, of ...single channel types with conductances in the ...
18
Ion channel activity of influenza A virus M2 protein: characterization of the amantadine block.
... The surface currents of oocytes Udorn M2 ion channel were 60 min M2 ion channels by amanexpressing the Rostock or measured, and then amantadine was appropriate concentration to the solut[r] ...
10
Temporal Control of Ion Channel Activation
... with ion channel ...voltage-sensitive ion chan- nels during activation [34–36]. Voltage-sensitive ion channels open under change in the polarization of the membrane, accomplished routinely in ...
186
Na+ Channel ß Subunits : Overachievers of the Ion Channel Family
... the ion channel pore, β subunits alter gating, voltage-dependence, and kinetics of VGSCα subunits and thus regu- late cellular excitability in ...in channel modulation, β subunits are members of the ...
12
Theory and experiments on multi ion permeation and selectivity in the NaChBac ion channel
... the ion channel as the selectivity ¯lter, which we treat as a 1D lattice (see ...1 ion and the bulk reservoirs contain mixed solutions of arbitrary ...
13
A Parallel Finite Element Simulator for Ion Transport through Three-dimensional Ion Channel Systems
... In this paper, we present a parallel adaptive finite element simulator, ichannel, for ion transport through ion channel systems. Numerical applications are carried out with the gramicidin A ...
34
The ion channel inverse problem: neuroinformatics meets biophysics
... studying ion channels and map out the additional components needed to bridge the gap between what is available from studies of ion channels and what is needed to construct reliable models for use in ...
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Ion channel diversity, channel expression and function in the choroid plexuses
... of ion channels making the separation of distinct transport pathways more ...most ion channels have been ...of channel expression in the choroid ...of ion channel structure and ...
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Practical considerations for the ion channel free-electron laser
... The ion-channel laser (ICL) has been proposed as an alternative to the free-electron laser (FEL), replacing the deflection of electrons by the periodic magnetic field of an undulator with the periodic ...
9
Hypoxic regulation of ion channel function and expression
... Such an effect is likely to be a major contributory factor in pulmonary hypertension associated with hypoxic adaptation. In the carotid body type I cell, maxi-K channel functional expression was suppressed in rats ...
11
Non-Canonical Ion Channel Behaviour in Pain
... ionic channel complement of the neuron; in C-high threshold mechanoreceptors which mediate slowly adapting mechanosensitive cation currents [66], I Kmech opposes depolarisation and increases ...
21
State of Ion Channel Research
... of ion channels that will allow, FOR THE FIRST TIME, measurements of current routinely in single channels, of known structure, mutated to have selectivity designed by the variational ...
7
Control of ion channel expression
... The possibility that translational control of a receptor subunit, other than the a subunit, is responsible for the apparent post-translational control of AChR expression seen in Bc;H-1 c[r] ...
176
Inhibition of the TRPC5 ion channel protects the kidney filter
... an excellent tool to isolate the contribution of TRPC5 channels in podocytes, because (a) TRPC4 is not expressed in podocytes (22) and (b) TRPC6, which acts antagonistically to TRPC5 channels in podo- cytes (22), remains ...
13
The first peptide gated ion channel
... neuronal channel and oocyte-expressed FaNaCh. The single-channel conductance of the neuronal channel is 4 pS, and it is 11–13 pS for the expressed ...
10