Jurkat T cell line
Dual acting stapled peptides target both HIV 1 entry and assembly
... the Jurkat T-cell line con- ferred nearly complete resistance to the peptides in virus replication assays in Jurkat cells (Figure 10), some inhibi- tory peptide activity remained when ...
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Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins.
... All constructs containing the HIV-1 direct repeats proved inducible in the Jurkat tax-9 cell line but not in the Jurkat anti-tax-10 cell line, suggesting that the observed induction of t[r] ...
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Original Article EDAG-1 promotes the proliferation of human T-acute lymphoblastic leukemia cells by activating MAPK/Erk and Akt signaling pathways
... of T-ALL cells. Firstly, we confirmed that EDAG-1 was highly expressed in T-ALL cell line Jurkat and peripheral blood cells of patients with T-ALL compared with the peripheral ...
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Transcriptional activation of the vascular cell adhesion molecule-1 gene in T lymphocytes expressing human T-cell leukemia virus type 1 Tax protein.
... HTLV-1-negative T-cell lines (Jurkat and CEM); (ii) two HTLV-1-transformed T-cell lines (MT2 [31] and C8166 [44]); (iii) three clones of Jurkat cells stably expressing Tax (28) ...
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Activation of the human T-cell leukemia virus type I enhancer is mediated by binding sites for Elf-1 and the pets factor.
... We have now shown that Elf-1 binds to PuBi and PuB2 in vitro and that Elf-1 binding or that of a closely related factor predominates in nuclear extracts from a human T-cell line Jurkat o[r] ...
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Ultrashort electric pulse induced changes in cellular dielectric properties
... of Jurkat cells, a malignant human T-cell line, before and after exposure to five 10 ns, 150 kV/cm electrical ...in cell suspension ...in cell membrane conductivity after the ...
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Lentiviral gene transfer into human and murine hematopoietic stem cells: size matters
... We set out to relate the length of the viral RNA to the efficiency of virus production as well as to the potency of these viral batches to transduce the T-cell acute lympho- blastic leukemia line ...
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Cellular CD44S as a determinant of human immunodeficiency virus type 1 infection and cellular tropism.
... predominant cell membrane protein that binds human immunodeficiency virus type 1 (HIV-1) gp120 and facilitates HIV-1 infection, but other membrane-associated molecules may be involved in determin- ing HIV-1 ...
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Down-regulation of HLA antigens by the adenovirus type 2 E3/19K protein in a T-lymphoma cell line.
... Jurkat cells transfected with the E3 region of Ad2 expressed E3/19K in the absence of EIA, and the intracellular interaction with HLA was comparable to that in 293E3-45, a cell line of n[r] ...
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Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat.
... 8 Activation of Endogenous c-fos Proto-Oncogene Expression by Human T-Cell Leukemia Virus Type I-Encoded p4Otax Protein in the Human T-Cell Line, Jurkat KINYA NAGATA, KIYOSHI OHTANI, MAS[r] ...
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Caspase 9 Is Essential for Herpes Simplex Virus Type 2-Induced Apoptosis in T Cells
... continued cell-mediated immunity demonstrates the ability of the virus to circumvent the host’s immune ...from T cells isolated from human HSV lesions, indicating that T cells are infected with HSV ...
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Disulfide bond formation in the human immunodeficiency virus type 1 Nef protein.
... To evaluate the effect of wild-type and cysteine mutant ELI and LAI Nef proteins on virus replication, the CD4+ T-cell line Jurkat and primary peripheral blood mononuclear cells PBMCs we[r] ...
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A Microfluidic Platform for Single Cell Fluorometric Granzyme B Profiling
... At present, biosensing platforms using fluorescence measurement have become a convention for detecting and quantifying biomolecules like DNAs, miRNAs, proteins, and enzymes for both bulk and single cell analysis. ...
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Phosphatidylserine dependent ingestion of apoptotic cells promotes TGF β1 secretion and the resolution of inflammation
... apoptotic cell recognition and clearance in fibrotic alterations needs to be ...of cell clearance and TGF- β amounts and effects that determines final ...
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Antiproliferative activities and phenolic acid content of water and ethanolic extracts of the powdered formula of Houttuynia cordata Thunb fermented broth and Phyllanthus emblica Linn fruit
... cordata fermentation products was partly attributed to the presence of p-coumaric, ferulic and sinapinic acids [20]. The phenolic components of P. emblica have been associated with inhibition of MCF7 cells in vitro [21]. ...
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A study of PD-L1 expression in KRAS mutant non-small cell lung cancer cell lines exposed to relevant targeted treatments.
... of T cell activation allowed us to test PDL-1 expression as a putative mechanism of resis- tance in a significant number of KRAS mutant cell lines relatively rapidly and ...the jurkat ...
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Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics
... 14-3-3 proteins are known to play a key role in integrating survival signaling within the cell [1-2]. When mutant forms of 14-3-3 that are non-competent for phospho-client binding are expressed in cells they ...
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Semi purified extracts of Commelina benghalensis (Commelinaceae) induce apoptosis and cell cycle arrest in Jurkat T cells
... Commelina benghalensis L. (CB) is used traditionally as either a food source for its nutritional value or in trad- itional medicine. The plant is widely used in traditional medicine in China and Nigeria [16,17]. In South ...
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The human T-cell leukemia virus type 1 Rex regulatory protein exhibits an impaired functionality in human lymphoblastoid Jurkat T cells.
... C91PL T cells ...the cell fractionation ...in Jurkat T cells is correlated with the inability of Rex to me- diate the nucleocytoplasmic transport of env unspliced ...in Jurkat T ...
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xCELLigence system for real-time label-free monitoring of growth and viability of cell lines from hematological malignancies
... real-time cell analysis of adherent tumor ...the cell culture surface with specific substrates, some of which are known to facilitate cell adhesion in the extracellular ...the cell growth and ...
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