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KEGG Pathways

Combining Gene Phenotype Association Matrix with KEGG Pathways to Mine Gene Modules  Using Data Set in GAW17

Combining Gene Phenotype Association Matrix with KEGG Pathways to Mine Gene Modules Using Data Set in GAW17

... significantly function aggregated genes. We found that more than half of the biclusters (54.5%) were signifi- cantly enriched on KEGG pathways. Table 2 lists the significantly (nominal p ≤ 0.05) enriched ...

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Unveiling transcription factor regulation and differential co-expression genes in Duchenne muscular dystrophy

Unveiling transcription factor regulation and differential co-expression genes in Duchenne muscular dystrophy

... (KEGG) pathways (http://www.genome.jp/kegg/) ...identify pathways significantly enriched with DEGs. In addition to KEGG pathway analysis, DEGs were also uploaded into the Ingenuity ...

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Pathway networks generated from human disease phenome

Pathway networks generated from human disease phenome

... and KEGG pathways ...3–95 KEGG pathways ...enriched KEGG pathways was Congenital, Hereditary, and Neonatal Diseases and Abnormalities (C16), with 95 pathways enriched (79% ...

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... KEGG pathways in Nfu muscle (blue), brain (yellow), liver (green) and skin (red) tissue comparing young versus old 31. samples[r] ...

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Transcriptome analysis of long non-coding RNA in the bovine mammary gland

Transcriptome analysis of long non-coding RNA in the bovine mammary gland

... Supplementary file 5: Gene ontology and KEGG pathways enriched for cis target genes of lncRNAs;. 497[r] ...

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Original Article Transcriptome analysis of primary aldosteronism in adrenal glands and controls

Original Article Transcriptome analysis of primary aldosteronism in adrenal glands and controls

... biological pathways was evaluated by ...35 KEGG pathways were enriched among genes differentially expressed in PA samples versus normal con- trols (Table 4), including ‘ribosome’, ‘oxidative ...

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Original Article Sputum metabolomic profiling of bronchial asthma based on quadruple time-of-flight mass spectrometry

Original Article Sputum metabolomic profiling of bronchial asthma based on quadruple time-of-flight mass spectrometry

... KEGG pathways representing the differentially expressed metabolites in asthma patients compared with healthy control using UHPLC- QTOF-MS in positive and negative mode were shown in Tables 3 and 4, ...

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Overcoming chemoresistance in prostate cancer with Chinese medicine Tripterygium wilfordii via multiple mechanisms

Overcoming chemoresistance in prostate cancer with Chinese medicine Tripterygium wilfordii via multiple mechanisms

... identify pathways significantly enriched with the DEGs. (KEGG, Kyoto Encyclopedia of Genes and Genomes, is a powerful database for understanding and simulating functional behaviors of cells or organisms ...

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Profiles of differentially expressed circRNAs in esophageal and breast cancer

Profiles of differentially expressed circRNAs in esophageal and breast cancer

... In KEGG pathway analysis, for the top 10 upregulated circRNAs in ESCC, HTLV-I infection, cancer, and cGMP- PKG signaling were the top three pathways (Figure ...three pathways (Figure S2B). Moreover, ...

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Identification of key pathways and hub genes in basal-like breast cancer using bioinformatics analysis

<p>Identification of key pathways and hub genes in basal-like breast cancer using bioinformatics analysis</p>

... enriched KEGG pathways related to ...in pathways such as cell cycle, cytokine–cytokine receptor interaction, chemokine signaling pathway, central carbon metabolism signaling and TNF signaling ...

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Identification and Bioinformatic Analysis of Circular RNA Expression in Peripheral Blood Mononuclear Cells from Patients with Chronic Obstructive Pulmonary Disease

<p>Identification and Bioinformatic Analysis of Circular RNA Expression in Peripheral Blood Mononuclear Cells from Patients with Chronic Obstructive Pulmonary Disease</p>

... three KEGG pathways (NOD-like receptor signaling pathway, natural killer cell mediated cytotoxicity and Th17 cell differentiation) and may act as the miRNA sponge regulating the ...

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Tools for visualization and analysis of molecular networks, pathways, and -omics data

Tools for visualization and analysis of molecular networks, pathways, and -omics data

... used KEGG Mapper and KEGGViewer as web-based visualization tools for KEGG ...pathways. KEGG Mapper creates a static image, whereas KEGGViewer allows users to loop over different conditions, ...

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A computational procedure for functional characterization of potential marker genes from molecular data: Alzheimer's as a case study

A computational procedure for functional characterization of potential marker genes from molecular data: Alzheimer's as a case study

... available KEGG pathways have been biologically validated before ...for KEGG and GO, we selected the WebGestalt human genome as reference set, p-value ≤ ...

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Expression profile of microRNAs in porcine alveolar macrophages after Toxoplasma gondii infection

Expression profile of microRNAs in porcine alveolar macrophages after Toxoplasma gondii infection

... The target genes of the miRNAs were predicted using miRanda software. The measure transcripts per million (TPM) was used to estimate miRNA expression levels based on the following criteria: normalized expression = mapped ...

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Metabolic responses to ethanol and butanol in Chlamydomonas reinhardtii

Metabolic responses to ethanol and butanol in Chlamydomonas reinhardtii

... metabolism” pathways were active in the exponential-stationary transition ...isms” pathways were significantly affected in at least two growth phases, suggesting that these pathways were very active ...

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Analysis of gene expression profiles and protein-protein interaction networks in multiple tissues of systemic sclerosis

Analysis of gene expression profiles and protein-protein interaction networks in multiple tissues of systemic sclerosis

... Based on the current results, it seems that common pathological pathways contribute to the pathogenesis of SSc in different tissues. However, tissue type may make it susceptible to the initiation of more compli- ...

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Exploring timing activation of functional pathway based on differential co-expression analysis in preimplantation embryogenesis

Exploring timing activation of functional pathway based on differential co-expression analysis in preimplantation embryogenesis

... functional pathways actively transcribes as early as the 2-cell and 4-cell waves, which Basal transcription factor, Endocytosis and Spliceosome pathway can represent first signs of embryonic ...functional ...

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Comprehensive characterization of the phosphoproteome of gastric cancer from endoscopic biopsy specimens

Comprehensive characterization of the phosphoproteome of gastric cancer from endoscopic biopsy specimens

... increased pathways in cancer, several pathways involved in genome instability and mutation, which is one hallmark of cancer, were identified based on both KEGG (Figure 4B, magenta) and WikiPathway ...

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Identification and characterization of microRNAs in the pituitary of pubescent goats

Identification and characterization of microRNAs in the pituitary of pubescent goats

... puberty. KEGG path- way annotations of miR-34c show that most of its target genes are involved in cancer signaling pathways and in actin cytoskeleton KEGG ...

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Original Article Serum metabolomic study for the detection of candidate biomarkers of tuberculosis

Original Article Serum metabolomic study for the detection of candidate biomarkers of tuberculosis

... Abstract: Tuberculosis (TB) is a widespread infectious disease caused by various strains of mycobacteria. Early diagnosis of this disease is important. However, only a few biochemical tests or markers are available for ...

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