killer immunoglobulin-like receptor
Killer Immunoglobulin-Like Receptor 2DL4 (CD158d) Regulates Human Mast Cells Both Positively and Negatively: Possible Roles in Pregnancy and Cancer Metastasis
... Killer immunoglobulin-like receptor (KIR) 2DL4 (CD158d) was previously thought to be a human NK-cell-specific protein but its expression has also been demonstrated in human mast ...IgE ...
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Ligand-Independent Exhaustion of Killer Immunoglobulin-Like Receptor-Positive CD8+ T Cells in Human Immunodeficiency Virus Type 1 Infection
... KIR ⴙ CD8 ⴙ T cells are enriched in HIV-specific memory CD8 ⴙ T cells. As described previously, KIR expression is re- stricted to memory CD8 ⫹ T cells (4, 29). These observations were confirmed in the context of HIV ...
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The favorable role of homozygosity for killer immunoglobulin-like receptor (KIR) A haplotype in patients with advanced-stage classic Hodgkin lymphoma
... natural killer (NK) cell function in ...several receptor families, including killer cell immunoglobulin-like receptors (KIRs) which recognize human leukocyte antigen (HLA) class I mole- ...
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A role for type 111 interferons in the natural killer cell immune response to virus
... IFN stimulated gene IFN stimulated gene factor IFN stimulated response elements Immunoreceptor tyrosine-based inhibitory motif Janus kinase Killer immunoglobulin -like receptor Lymphokin[r] ...
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Killer cell Immunoglobulin like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women
... Leukocyte immunoglobulin-like receptors (LILR), the C-type lectin receptors-NKG2A-F, and the natural cytotoxic receptors (NCRs) -NKp30, NKp44 and ...
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Role of KIR and CD16A genotypes in colorectal carcinoma genetic risk and clinical stage
... between killer immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) class I ligands on target cells and the different binding affinity of the Fcγ receptor IIIA (CD16A) for ...
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Monoclonal yeast killer toxin-like candidacidal anti-idiotypic antibodies.
... yeast killer toxin (KT)-like immunoglobulin M (IgM) anti-idiotypic antibodies (KT-IdAbs) were produced by idiotypic vaccination with a mouse monoclonal antibody (MAb; MAb KT4) that neutralized a ...
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Effect of Killer Immunoglobulin-Like Receptors in the Response to Combined Treatment in Patients with Chronic Hepatitis C Virus Infection
... cell immunoglobulin-like receptors (KIRs) are mem- bers of a group of regulatory molecules expressed on NK cells and a subset of T cells ...leukocyte receptor complex. The leukocyte receptor ...
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Activation of human eosinophils through leukocyte immunoglobulin-like receptor 7
... containing phosphatase 1 to the phosphorylated immunorecep- tor tyrosine-based inhibitory motif to inhibit or terminate signaling through nonreceptor tyrosine kinase cascades (14). The activating LIRs (LIRs 6a, 6b, and 7 ...
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Expression of the Pseudorabies Virus gB Glycoprotein Triggers NK Cell Cytotoxicity and Increases Binding of the Activating NK Cell Receptor PILRβ
... Natural killer (NK) cells are components of the innate immunity and are key players in the defense against virus-infected and malignant ...that, like their human and murine counterpart, porcine NK cells ...
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Killer cell immunoglobulin–like receptor 3DL1 variation modifies HLA B*57 protection against HIV 1
... inhibitory killer cell immunoglobulin-like receptor KIR3DL1 as the only significant modifier of B*57 ...cell receptor that binds B*57:01 modifies its ...
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Killer Cell Immunoglobulin-Like Receptors (KIRs) Genotype and Haplotype Analysis in Iranians with Non-Melanoma Skin Cancers
... The high prevalence of cancers has been observed in individuals with defective NK cell functions [29] . A long-term epidemiological study has reported that individuals with low NK cell activity are prone to high risk of ...
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Killer-cell Immunoglobulin-like Receptor gene linkage and copy number variation analysis by droplet digital PCR
... the Killer-cell Immunoglobulin-like Receptors (KIRs) ...natural killer (NK) cell recep- tors, their roles in modulating outcomes of infectious diseases [2,3], transplantation [4] and pregnancy ...
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Reproduction, infection and killer cell immunoglobulin like receptor haplotype evolution
... reproduction (Parham 2005, 2008; Parham and Moffett 2013). This is in keeping with the observation that KIR A homozy- gous individuals exhibit better clearance of hepatitis C infec- tion (Khakoo et al. 2004), but KIR B ...
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HLA and killer cell immunoglobulin-like receptor (KIRs) genotyping in patients with acute ischemic stroke
... PE: Immunoglobulin gG2a conjugated with phycoerythrine; KIRIIND: KIR Infectious and Inflammatory Disease Collaborative Group; KIRs: Killer cell immunoglobulin-like receptor; LAAS: Large ...
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The role of NK cells in HIV-1 protection: autologous, allogeneic or both?
... Natural killer (NK) cells specialize in killing virally infected- or tumor cells and are part of the innate immune sys- ...by receptor-ligand binding with the target cell. These receptor-ligand bonds ...
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Role of persistent CMV infection in configuring T cell immunity in the elderly
... by killer cell inhibitory receptors, which can be divided into two struc- tural types, killer immunoglobulin-like receptors (KIR) and killer cell lectin-like receptor ...
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Natural Killer Cell Dysfunction in Hepatocellular Carcinoma: pathogenesis and clinical implications
... narrow killer-cell immunoglobulin-related receptor (KIR) profile that indicates a clonal-like expansion ...inhibitory receptor natural killer group 2 member A (NKG2A), which ...
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Immunological and virological investigations into sporadic ovine lymphoma : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University
... surface membrane immunoglobulin receptor for aggregated IgG receptor for antibody- coated bovine erythrocytes receptor for antibody-coated human erythrocytes receptor for erythrocyte - a[r] ...
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VEGF - A Precis’
... additional receptor for VEGF that was known to be a neuronal recognition molecule and a neuronal cell adhesion molecule, namely the ...enhance receptor binding but also prolong the signal ...
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