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kit ligand

An Allelic Series of Mutations in the Kit ligand Gene of Mice. I. Identification of Point Mutations in Seven Ethylnitrosourea-Induced KitlSteel Alleles

An Allelic Series of Mutations in the Kit ligand Gene of Mice. I. Identification of Point Mutations in Seven Ethylnitrosourea-Induced KitlSteel Alleles

... al., 1991 Glycosylated and unglycosylated recombinant-derived Huang, E. J., K. Manova, A. I. Packer, S. Sanchez, R. F. Bachvarova human stem cell factors are dimeric and have extensive regular et al., 1993 The murine ...

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Kit ligand promotes first polar body extrusion of mouse preovulatory oocytes

Kit ligand promotes first polar body extrusion of mouse preovulatory oocytes

... candidate ligand-receptor pairs potentially involved in the process of oocyte maturation ...of kit ligand (Kitl, also known as stem cell factor) during the preovulatory ...

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Oocyte-granulosa cell interactions during mouse follicular development: regulation of kit ligand expression and its role in oocyte growth

Oocyte-granulosa cell interactions during mouse follicular development: regulation of kit ligand expression and its role in oocyte growth

... Ovarian folliculogenesis is regulated by both endocrine and intraovarian mechanisms that coordinate the processes of oocyte growth and somatic cell proliferation and differentiation. Within the follicle, paracrine ...

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Glucocorticoids decrease tissue mast cell number by reducing the production of the c kit ligand, stem cell factor, by resident cells: in vitro and in vivo evidence in murine systems

Glucocorticoids decrease tissue mast cell number by reducing the production of the c kit ligand, stem cell factor, by resident cells: in vitro and in vivo evidence in murine systems

... Materials. DME, glutamine, penicillin, and streptomycin (Gibco Laboratories, Grand Island, NY); FBS (Bioproducts for Science, Inc., Indianapolis, IN); water-soluble dexamethasone (Sigma Chemical Co., St. Louis, MO); ...

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Nurr1 dependent regulation of pro-inflammatory mediators in immortalised synovial fibroblasts

Nurr1 dependent regulation of pro-inflammatory mediators in immortalised synovial fibroblasts

... and Kit ligand were upregulated more than 2-fold and subsequently returned to basal levels by the presence of the Nurr1 dominant negative, confirming the Nurr1 ...and Kit ligand also have ...

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The developmental origins of the mammalian ovarian reserve

The developmental origins of the mammalian ovarian reserve

... This research found that KIT-ligand also called stem cell factor, SCF; or Steel factor is highly expressed at the oocyte membrane, specifically during the window of cyst breakdown and pr[r] ...

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Contrasting signals of positive selection in genes involved in human skin-color variation from tests based on SNP scans and resequencing

Contrasting signals of positive selection in genes involved in human skin-color variation from tests based on SNP scans and resequencing

... Skin pigmentation is an excellent candidate system for investigating positive selection. It is very likely that this trait is under selective pressure, given the biological role of pigmentation and the large differences ...

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GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement

GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement

... its ligand SCF (also termed Kit ligand), are involved in human and murine HSPC motility (26–30), pointing to a signaling pathway that uniquely regulates the migration of immature hematopoietic cells ...

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The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy

The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy

... Stromal cells, on the other hand, facilitate tumor growth and tumor dissemination mostly by regulating cancer cell adhesion and contributing to cell proliferation and survival. It was shown that hypoxia induces stromal ...

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Original Article Intranasal sirna targeting c-kit reduces airway inflammation in experimental allergic asthma

Original Article Intranasal sirna targeting c-kit reduces airway inflammation in experimental allergic asthma

... eosinophils expressed and released SCF, and blocking c-kit/c-kit ligand interaction could significantly decrease eosinophils in the BALF [27, 28]. Moreover, SCF also induced the adhe- sion of ...

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c KIT expression enhances the leukemogenic potential of 32D cells

c KIT expression enhances the leukemogenic potential of 32D cells

... The growth of human leukemic cells in culture and in vivo is dependent upon the presence of hematopoietic growth factors. Most populations of human leukemic acute myeloblastic leukemia (AML) cells express c-Kit on ...

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Is c-kit Gene Product involved in Epithelial-
Mesenchymal Transition in Tongue Squamous Cell Carcinoma? A Pilot Study Oriented Towards Patient Outcome

Is c-kit Gene Product involved in Epithelial- Mesenchymal Transition in Tongue Squamous Cell Carcinoma? A Pilot Study Oriented Towards Patient Outcome

... the kit-ligand (SCF) [15,20,39,40] mast cell growth factor [5] or steel factor, [6-8] is essential to melanocyte and germ cell development and the early stages of ...its ligand, SCF, in colon cancer ...

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Comparison of commercial RNA extraction kits for preparation of DNA free total RNA from Salmonella cells

Comparison of commercial RNA extraction kits for preparation of DNA free total RNA from Salmonella cells

... UltraClean kit were about 5 - 19-fold lower than those produced by the other ...this kit compared to the others (Table ...UltraClean kit is unsuitable for applications such as the detection of invA ...

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Original Article Membrane estrogen receptor alpha is an important modulator of bone marrow C-Kit cells mediated cardiac repair after myocardial infarction

Original Article Membrane estrogen receptor alpha is an important modulator of bone marrow C-Kit cells mediated cardiac repair after myocardial infarction

... Formalin fixed hearts were processed, embed- ded in paraffin and cut as 5 μm-thick sections. After deparaffinization and blocking, Masson Trichrome staining, and Sirius red staining were done on the same series of heart ...

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Repurposing Ponatinib as a Potent Agent against KIT Mutant Melanomas

Repurposing Ponatinib as a Potent Agent against KIT Mutant Melanomas

... USA): KIT (#3074), phospho–KIT (Tyr719, #3391), AKT (#4685), phospho-AKT (Ser474, #4060), ERK1/2 (#4695), phospho-ERK1/2 (Tyr202/Tyr204, #4370), and GAPDH ...(TUNEL) KIT and CCK-8 KIT were ...

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Identification of mutations in the coding sequence of the proto oncogene c kit in a human mast cell leukemia cell line causing ligand independent activation of c kit product

Identification of mutations in the coding sequence of the proto oncogene c kit in a human mast cell leukemia cell line causing ligand independent activation of c kit product

... was ligand independent. Sequencing of whole coding region of c-kit cDNA revealed that c-kit genes of HMC-1 cells were composed of a normal, wild-type allele and a mutant allele with two point ...

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Family Conversation Kit

Family Conversation Kit

... the upgraded modular documenting recipe design 6.4 Visualized conversations and identity color It was proved that more examples were needed for people to make connections from topic icon[r] ...

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A Homicide Investigation Kit

A Homicide Investigation Kit

... About a year ago the staff of the collection and preservation of evidence, Chicago Police Scientific Crime Detec- and, in addition, there is included the tion Laboratory designed and pre[r] ...

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Apple VideoPhone Kit

Apple VideoPhone Kit

... VideoPhone Kit CD, you need to specify the CD as the startup disk in the Startup Disk control ...VideoPhone Kit CD icon, then close the control panel and restart your ...

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The Supertree Tool Kit

The Supertree Tool Kit

... Findings: The aim of the Supertree Tool Kit (STK) is to aid in the collection, storage and processing of input source trees for use in supertree analysis. It is therefore invaluable when creating supertrees ...

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