Lens epithelium
Ultraviolet-B induces ERCC6 repression in lens epithelium cells of age-related nuclear cataract through coordinated DNA hypermethylation and histone deacetylation
... human lens epithelium B3 (HLE-B3) and 239T cell caused an orches- trated epigenetic and transcriptomic changes in the con- text of ERCC6 ...human lens tissue of ARNCs collected from cataract ...
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Different alpha crystallin expression in human age-related and congenital cataract lens epithelium
... the lens epithelium might be involved in cataracto- ...the lens epithelium was significantly greater in the congenital cataract than in the age-related cataract ...the lens ...
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Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia
... The lens metabolizes actively and requires nourishment to maintain its growth and ...the lens need lower energy demands, lack of aerobic respiration and consume little oxygen comparing to other tissues in ...
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The ubiquitin proteasome system is required for cell proliferation of the lens epithelium and for differentiation of lens fiber cells in zebrafish
... in lens epithelium by EdU ...Pax6-positive lens cells as epithelial cells with the margin associated with the retinal CMZ ...wild-type epithelium, 30-40% of cells were labeled with EdU from 36 ...
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Overexpression of the Lens Epithelium-Derived Growth Factor/p75 Integrase Binding Domain Inhibits Human Immunodeficiency Virus Replication
... We initially identified lens epithelium-derived growth factor/p75 (LEDGF/p75) as a binding partner of human immunodeficiency virus type 1 (HIV-1) integrase. To investigate the role of LEDGF/p75 in HIV ...
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Characterisation of lens epithelium derived growth factor isoforms in chronic lymphocytic leukemia: Studies and significance
... Recent evidence indicates that augmented states of cellular oxidative stress contribute to the development of cancers 82, 84 . LEDGF/p75 is a known stress- response protein that binds to STRE and HSE and activates ...
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Observations of Lens Epithelium in Cell Cultures
... There were no observable differences in the mor- phological characteristics of the cells and of the growth pattern among the various specimens, regard- less of whet[r] ...
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Cell division and cadherin mediated adhesion regulate lens epithelial cell movement in zebrafish
... clarify lens epithelial tension, we used a laser to ablate single cells in the anterior lens epithelium of the transgenic line Tg(h2afva:GFP; EF1 α :mCherry-CAAX), and performed time-lapse imaging to ...
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Five-year incidence of Nd:YAG laser capsulotomy and association with in vitro proliferation of lens epithelial cells from individual specimens: a case control study
... the lens epithelial cells of that individual or if they are due to individual-dependent systemic factors or differences in the ocular milieu surrounding the lens cells in ...individual lens ...
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Profiling of chromatin accessibility and identification of general cis -regulatory mechanisms that control two ocular lens differentiation pathways
... P0.5 lens epithelium and lens fibers by ATAC‑seq To identify and characterize chromatin dynamics dur- ing mouse lens differentiation, we collected ...P0.5 lens epithelial and fiber ...
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Electron Microscopic Investigation of Anterior Lens Capsule and Epithelium in Patients with Diabetes Mellitus
... anterior lens capsule in patients with diabetes mellitus by using electron microscopy and to compare it between diabetic eyes and healthy ...group, lens epithelial cells and all their elements had a normal ...
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Detection of autoantibodies to DSF70/LEDGFp75 in Mexican Hispanics using multiple complementary assay platforms
... Purpose Antinuclear autoantibodies (ANA) targeting the dense fine speckled antigen DFS70, also known as lens epithelium-derived growth factor p75 (LEDGF/p75), are attracting attention du[r] ...
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Integration of HIV-1 DNA Is Regulated by Interplay between Viral Rev and Cellular LEDGF/p75 Proteins
... The present work describes a novel interaction between the human immunodeficiency virus type 1 (HIV-1) Rev protein and the cellular lens epithelium-derived growth factor p75 (LEDGF/p75) protein in vitro and ...
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Key determinants of target DNA recognition by retroviral intasomes
... protein lens epithelium-derived growth factor (LEDGF)/p75 directs integration to active genes [23-26], whereas bromodo- main and extraterminal domain (BET) proteins BRD2, 3, and 4 interact with Moloney ...
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Automated tests of ANA immunofluorescence as throughput autoantibody detection technology: strengths and limitations
... speckled/lens epithelium-derived growth factor; DM: Dermatomyositis; IIF: Indirect immunofluorescence; JIA: Juvenile idiopathic arthritis; MCTD: Mixed connective tissue disease; MSA: mitotic spindle ...
5
Influence of energy balance on the antimicrobial peptides S100A8 and S100A9 in the endometrium of the post-partum dairy cow.
... luminal epithelium, thus firmly links upregulation of S100A8 and S100A9 to an ongoing inflammatory process in response to bacterial contami- nation after ...
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Mapping the distribution of stem/progenitor cells across the mouse middle ear during homeostasis and inflammation
... Fig. 3. High levels of Sox2 expression and Wnt activity restricted to the endodermally derived part of the middle ear. (A-D) Whole-mount preparation of auditory bullae (AB) at P21 after ear drum removal showing the ...
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A prospective study of visual outcome in lens induced glaucomas following surgery
... 413 (1.5%) OF 27,073 senile cataracts seen in the outpatient department of Sagarematha Chaundhaey Eye Hospital, Lahan, Nepal presented with Lens induced Glaucoma. There were 298 (72%) phacomorphic cases and 115 ...
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Comparison of Visian toric collamer lens and toric acrylic intraocular lens implantation for the treatment of myopia with astigmatism
... Pupil dilation was performed with cyclopentolate HCl 1% and phenylephrine 2.5% eye drops instilled 1 hour prior to surgery. A horizontal axis marking at slit lamp was performed immediately before surgery to avoid the ...
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Pax6 dependent Shroom3 expression regulates apical constriction during lens placode invagination
... actin/myosin network, and disruptions in morphogenesis often accompany mutants that affect this network (Lecuit and Lenne, 2007). It is likely that the mislocalization of F-actin and myosin II in Shroom3 mutants is ...
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