Leptin level
Effect of Methanolic Extract of Phyllanthus niruri on Leptin Level in Animal Model of Diabetes Mellitus
... In light of the present results, our work indicates that methanolic extracts of P.niruri have good anti-diabetic activity. Our study showed significant improvement in anti-oxidant parameters i.e. increase in GSH & ...
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OBESITY, INFLAMMATION AND METABOLIC SYNDROME
... serum leptin, TNF- α were measured using ELISA methods and serum triglycerides, cholesterol and lipid profile in normal and overweight BMI subjects were ...Interestingly leptin level was found to be ...
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Comparison of plasma leptin levels in patients with normal, low and high risk myocardial perfusion scan [Persian]
... Conclusion: Serum leptin level shows no correlation with coronary artery disease risk category or factors (excluding BMI). Key words: Leptin, Myocardial perfusion imaging, BMI[r] ...
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New advances in the treatment of generalized lipodystrophy: role of metreleptin
... metreleptin, and had their metabolic profile assessed at 1, 2, 3, and 4 months postinitiation of recombinant therapy. During treatment, the serum leptin level increased from a mean of 1.3 ± 0.3 ng/mL to ...
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ESTIMATION OF SERUM AND ASCITIC FLUID LEPTIN LEVELS IN CHRONIC LIVER DISEASE
... between leptin level and BMI in all studied ...the leptin level and BMI in patient that have post hepatitis liver cirrhosis are wasted and may be over dehydrated thus, the excess in ...
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Dose dependent relationship between serum metformin levels and glycemic control, insulin resistance and leptin levels in females newly diagnosed with type 2 diabetes mellitus
... and leptin level) in females with type 2 ...glucose level and increasing the insulin sensitivity without increasing of insulin secretion [19] with de- creasing the markers of insulin resistance ...
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Programming of mouse obesity by maternal exposure to concentrated ambient fine particles
... regulation. Leptin is a hormone primarily produced by adipose tissues and mediates long-term regulation of energy balance through suppressing food intake and affecting energy ...central leptin signaling, as ...
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Serum levels of leptin in Nigerian patients with sickle cell anaemia
... markers during steady and unsteady states of SCD [1,2,10]. Nevertheless, there may be a need to investigate other more specific inflammatory markers such as b 2- macroglobulin and C-reactive protein in our SCA cohort in ...
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To study leptin levels in overweight and obese individuals and correlate with ambulatory blood pressure abnormalities
... serum leptin levels and this indicates a state of leptin resistance, marked by impaired leptinaction and ...between leptin and β-cell function and increases the chances of development of insulin ...
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Effect of Plasma-leptin on Cardiac Disorders with Type 2 Diabetes-patients
... between leptin and adiponectin, in diabetic-cases, is highly correlated with heart rate variability ...neuron, Leptin activates proopiomelano- cortin (POMC) ...serum leptin level tends to be ...
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Leptin and the leptin receptor : Molecular and genetic studies
... serum leptin concentration was observed between 16 and 28 weeks in subjects who were non-smokers but had a poor pregnancy ...that leptin is a necessary factor in placental development and therefore in ...
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New insights into different adipokines in linking the pathophysiology of obesity and psoriasis
... pression level of chemerin dramatically increases during the cellular differentiation of pre-adipocytes, and the in- creased chemerin could in turn stimulate the adipogene- sis differentiation, leading to ...
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Phocid seal leptin : tertiary structure and hydrophobic receptor binding site preservation during distinct leptin gene evolution
... divergent leptin gene and dive to great ...phocid leptin. The function of leptin in the lung of the foetus is to provide additional surfactant when the lungs need to fill with air for the first time ...
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Original Article Leptin induces partial epithelial-mesenchymal transition in a FAK-ERK dependent pathway in MCF10A mammary non-tumorigenic cells
... Immunofluorescence and F-actin staining MCF10A cells were seeded on glass coversilps and grown to 70% confluence, then stimulated with or without leptin during 24 h. Cells were fixed with 4% paraformaldehyde and ...
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Short Term International Study For Teachers As A Form of Experiential Learning: A Case Study of American Educators in Turkey
... both leptin and LPS showed a marked increase in the gp91/p47 phox colocalization events while administration of SsnB (100 µg/ml) resulted in a significant decrease of the events (Figure ...
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Diet induced obese mice develop peripheral, but not central, resistance to leptin
... Serum leptin levels in AKR mice on 45% fat diet were highly correlated with increasing body weight ( y 5 ...serum leptin con- centrations from chow-fed or 10% fat-fed AKR mice and chow-fed, 10% fat-fed, and ...
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Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis
... anti-mouse leptin Abs injected either from day –1 to day 1 or on days 8–11 (100 µg/d ...i.p.). Leptin blockade significantly reduced clinical score and body weight loss (see Table ...
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2018_Gung.pdf
... proliferation. Leptin therefore may mediate obesity-induced breast cancer progression through multiple mechanisms ...subtype. Leptin signaling may contribute to this link, as obesity has been shown to ...
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Leptin inhibits 4 aminopyridine– and pentylenetetrazole induced seizures and AMPAR mediated synaptic transmission in rodents
... of leptin on AMPAR- and NMDAR-mediated EPSCs. Leptin inhib- ited AMPAR-mediated EPSCs and fEPSPs in a similar manner, except that only partial recovery occurred with washout (Figure ...5A). Leptin at ...
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Monogenic forms of childhood obesity due to mutations in the leptin gene
... the leptin gene to an adenine ...serum leptin levels were very low in both patients ...p.N103K leptin and demonstrated that the ...p.N103K leptin may contribute to the phenotype ob- served in ...
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