Leukemia and lymphomas
Frequent isolation of ecotropic murine leukemia virus after x-ray irradiation of C57BL/6 mice and establishment of producer lymphoid cell lines from radiation-induced lymphomas.
... 1 Frequent Isolation of Ecotropic Murine Leukemia Virus After X-Ray Irradiation of C57BL/6 Mice and Establishment of Producer Lymphoid Cell Lines from Radiation-Induced Lymphomas Fractio[r] ...
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Lymphomas and High-Level Expression of Murine Leukemia Viruses in CFW Mice
... murine leukemia viruses (MuLVs) have been rare and ...were lymphomas, the majority of B-cell ...routes. Lymphomas were induced in NIH Swiss mice infected as neonates with tissue culture-propagated ...
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Common proviral integration region on mouse chromosome 7 in lymphomas and myelogenous leukemias induced by Friend murine leukemia virus.
... 2 Common Proviral Integration Region on Mouse Chromosome 7 in Lymphomas and Myelogenous Leukemias Induced by Friend Murine Leukemia Virus JONATHAN SILVER* AND CHRISTINE KOZAK Laboratory [r] ...
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Identification of a common viral integration region in Cas-Br-E murine leukemia virus-induced non-T-, non-B-cell lymphomas.
... Common proviral integration region on a mouse chromosome 7 in lymphomas and myelogenous leukemias induced by Friend murine leukemia virus.. fim-1 andfim-2: two new integration regions of[r] ...
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Idelalisib therapy of indolent B-cell malignancies: chronic lymphocytic leukemia and small lymphocytic or follicular lymphomas
... 8. Eichhorst B, Fink AM, Busch R, et al. Frontline chemoimmunotherapy with fludarabine (F), cyclophosphamide (C), and rituximab (R)(FCR) shows superior efficacy in comparison to bendamustine (B) and rituximab (BR) in ...
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Stability of AML1 (core) site enhancer mutations in T lymphomas induced by attenuated SL3-3 murine leukemia virus mutants.
... The lack of enhancer reversion allowed analysis of the pathogenic spectra of AML1 site I-mutated viruses as such. To address the possibility of a change in tumor phenotype further, we analyzed tumors induced by the ...
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AHI-1: a novel signaling protein and potential therapeutic target in human leukemia and brain disorders
... of leukemia and ...cell leukemia (Figure 1) [39], 5% of the Moloney MuLV-induced rat thymomas [38], 11% of the Hoxa9/ Meis1-induced murine acute myeloid leukemia [40] and in acute myeloid leukemias ...
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Second-site proviral enhancer alterations in lymphomas induced by enhancer mutants of SL3-3 murine leukemia virus: negative effect of nuclear factor 1 binding site.
... SL3-3 is a highly T-lymphomagenic murine retrovirus. Previously, mutation of binding sites in the U3 repeat region for the AML1 transcription factor family (also known as core binding factor [CBF], polyomavirus enhancer ...
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Association of recombinant murine leukemia viruses of the class II genotype with spontaneous lymphomas in CWD mice.
... EcoRI cleaves within the gp7O gene of nearly all polytropic and xenotropic MuLV proviruses, but does not recognize sequences within the envelope genes of Downloaded from http://jvi.asm.o[r] ...
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Distinct helper virus requirements for Abelson murine leukemia virus-induced pre-B- and T-cell lymphomas.
... Although we cannot exclude the possibility that some tumors contain recombinant proviruses having deleted or rearranged both their LTR and gp7O region, our data show that more than one-h[r] ...
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Specificity of cell surface virus receptors on radiation leukemia virus and radiation-induced thymic lymphomas.
... Unlabeled blocking viruses in 1:1 and 3:1 ratios of unlabeled to fluoresceinated RadL V/VL3: BL/KaB, - -;BL/KaX,....; RadLV/VL3, titation of the amount of virus bound per cell and the ra[r] ...
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Moloney murine leukemia virus-induced lymphomas in p53-deficient mice: overlapping pathways in tumor development?
... We noted that MCF virus-like elements were generated in many of the tumors examined here but were significantly un- derrepresented in lymphomas of p53 2/2 mice. This does not simply reflect the lower number of ...
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flvi-1, a common integration domain of feline leukemia virus in naturally occurring lymphomas of a particular type.
... Three probes known to demonstrate somatic rearrangement of immunoglobulin loci in murine B cells were used in Southern blot analysis of the collection of feline lymphomas: i a 2.0-kb Bam[r] ...
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Cellular DNA regions involved in the induction of rat thymic lymphomas (Mlvi-1, Mlvi-2, Mlvi-3, and c-myc) represent independent loci as determined by their chromosomal map location in the rat.
... LOHSE,1 CLAUDE SZPIRER,2 JOSIANE SZPIRER,2 AND GORAN LEVAN3 Received 14 May 1985/Accepted 20 August 1985 The induction of thymic lymphomas by Moloney murine leukemia virus in the rat is [r] ...
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Increased lymphomagenicity and restored disease specificity of AML1 site (core) mutant SL3-3 murine leukemia virus by a second-site enhancer variant evolved in vivo.
... The AML1 site I-II mutant has been tested before and was found to be virtually nonpathogenic. In the present study, however, a mouse strain more susceptible to disease induction was used. This resulted in tumor ...
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cancer
... Lung Breast Colon Colon Bladder Bladder Prostate Prostate (Men) (Men) Leukemia Leukemia (Blood Cells) (Blood Cells) Lymphomas Lymphomas.. (Lymph nodes &tissues)![r] ...
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A 3' end fragment encompassing the transcriptional enhancers of nondefective Friend virus confers erythroleukemogenicity on Moloney leukemia virus.
... The parental clones were digested with the enzymes indi- Moloney murine leukemia virus Mo-MuLV induces T cell lymphomas after injection into newborn NFS mice, whereas the nondefective Fr[r] ...
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Proviral genome of radiation leukemia virus: molecular cloning of biologically active proviral DNA and nucleotide sequence of its long terminal repeat.
... per ml and inoculated as 50-,lI samples intrathymically Radiation leukemia virus RadLV is an in vivo-passaged murine leukemia virus MuLV complex, isolated from thymic lymphomas of X-ray-[r] ...
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Increased Induction of Osteopetrosis, but Unaltered Lymphomagenicity, by Murine Leukemia Virus SL3-3 after Mutation of a Nuclear Factor 1 Site in the Enhancer
... Both activating and repressing functions of NF1 are known, and even instances in which the same enhancer is variously repressed or activated by NF1 complexes depending on cell type have been described (4, 14, 25). It is ...
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Molecular cloning of osteoma-inducing replication-competent murine leukemia viruses from the RFB osteoma virus stock.
... A number of molecularly cloned ecotropic, N-tropic murine leukemia viruses MLVs induce osteomas benign bone tumors and osteopetrosis together with malignant lymphomas when the viruses ar[r] ...
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