Leukotriene C4 (LTC4)
Properties of highly purified leukotriene C4 synthase of guinea pig lung
... Leukotriene C4 (LTC4) synthase, which conjugates LTA4 and LTA4-methyl ester (LTA4- me) with glutathione (GSH) to form LTC4 and LTC4-me, respectively, has been solubilized from the ...
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Specific receptors for leukotriene C4 on a smooth muscle cell line
... for leukotriene C4 (LTC4) have been identified on an intact smooth muscle cell line, DDT1 MF-2 cells derived from the Syrian hamster vas ...unlabeled LTC4, LIGAND analysis of the Scatchard ...
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Release of leukotriene C4 by isolated, perfused rat small intestine in response to platelet activating factor
... We reported a rat model of necrotizing enterocolitis by injecting platelet-activating factor (PAF) into the mesenteric vascular bed, and suggested that leukotrienes (LT) are secondary mediators. The present study, using ...
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Molecular Cloning of the Human Leukotriene C4 Synthase Gene and Assignment to Chromosome 5q35
... The chromosomal localization was elicited rat peritoneal macrophages four to six ztermined by scoring the presence or absence of times above the levels in resting macrophages .e LTC4-spe[r] ...
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Accumulation of leukotriene C4 and histamine in human allergic skin reactions
... (e.g., LTC4, LTD4, and LTE4) and leukotriene B4 (LTB4), using radioimmune assay and HPLC separation, and compared it to histamine (assayed radioenzymatically) in 13 atopic and two nonatopic ...HPLC, ...
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Eosinophils altered phenotypically and primed by culture with granulocyte/macrophage colony stimulating factor and 3T3 fibroblasts generate leukotriene C4 in response to FMLP
... ng LTC4/10(6) cells, and LTC4 biosynthesis was blocked by N- tertbutoxy-carbonyl-L-methionyl-L-leucyl-L-phenylalanine ...of LTC4 from endogenous arachidonic acid nor substrate-initiated production of ...
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Leukotriene C4 binds to human glomerular epithelial cells and promotes their proliferation in vitro
... determine the identity of such macrophage-derived growth factors, we studied the effect of leukotrienes (LTs), products that are released from macrophages and leukocytes, on proliferation of human glomerular epithelial ...
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Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2
... The unique granular proteins of eosinophils may have a pathogenetic role in asthma and in the defense against parasitic infestations. However, the mechanisms regulating eosinophil degranulation are largely unknown. We ...
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Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin intolerant asthma
... We found that counts of eosinophils EG11 and EG21, mast cells AA11, macrophages CD681, and T cell subsets CD31, CD41, and CD81 were not significantly different in bronchial biopsies 20 m[r] ...
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Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3
... Human eosinophils were cultured in the presence of recombinant human IL-3 for up to 14 d and their biochemical, functional, and density properties were assessed. After 3 d of culture in 10 pM IL-3, eosinophils had a ...
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Association between copy number variation of complement component C4 and Graves' disease
... allele that results in partial C4 deficiency have shown to be risk factor for susceptibility in systemic lupus erythe- matosus (SLE) and the SLE-related renal damage [7,19]. A hypothesis is that complement may ...
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Further refinement of diaqua(1,7,11,17 tetraoxa 2,6,12,16 tetraazacycloeicosane N,N′,N′′,N′′′)nickel(II) dichloride† †
... from 0.050 and 0.136, respectively, to the corresponding values given below. The introduction of disorder into the model, whereby C4 and C7 are both distributed over pairs of sites as C4/C4A and C7/C7A with ...
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A generalized stoichiometric model of C3, C2, C2+C4, and C4 photosynthetic metabolism.
... magnitude of CO2 flux diffusing out of the BS, Eqn S19 Linear electron flow flow of electrons derived from the photo-oxidation of water Mesophyll Malate, MAL diffusion rate, respectively[r] ...
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Agıng and Pseudoexpholıatıon Syndrome; Is Sudden Cardıac Death Common Poınt of These?
... Volume 4, Issue 8, August – 2019 International Journal of Innovative Science and Research Technology ISSN No 2456 2165 IJISRT19AUG450 www ijisrt com 37 Agıng and Pseudoexpholıatıon Syndrome; Is Sudden[.] ...
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The effects on technology usıng effıcacy of teacher candıdates of educatıon faculty currıculum
... Reasons Thanks to the courses of computer laboratory, instructional technologies and material design Thanks to the assignments given in courses Thanks to the professors’ use of technolog[r] ...
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Cervical Diskography: Analysis of Provoked Responses at C2–C3, C3–C4, and C4–C5
... All patients in the series had undergone preliminary exam- ination of the cervical spine with high-field MR imaging (40 patients) and thin-section CT (10 patients) within 12 months of diskography. Any patient whose ...
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Closed Neighbourhood Prime Labeling(cnp) Ofgraph : A New Labeling Technique.
... Proof : Path union of C4 denoted by Pn(C4) is obtained by starting with a path Pn on n vertices given by (v1,v2,…vn) and n copies of C4 are taken.A copy each of C4 is fused at every ver[r] ...
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Analysis of C4 and the C4 binding protein in the MRL/lpr mouse
... The C3 and C4 levels in serum were measured by semiquan- titative ELISA. Plates were coated with either goat anti-mouse C3 (Cappel) or rat anti-mouse C4 (Accurate) in carbonate buffer (pH 9.6) and were ...
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Angola joint annual report 2001-2002
... ANNEX III - 1: Forecast of primary commitments Country: Angola Unit EDF or Sector AIDCO BL 1 Title of project/programme C7 C5 C5 C5 C6 C5 F5 F5 F3 C1 C4 C4 C4 C5 C4 C4 C4 F4 Focal Sector[r] ...
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Stimulation by leukotriene D4 of increases in the cytosolic concentration of calcium in dimethylsulfoxide differentiated HL 60 cells
... leukotrienes C4 (LTC4) and D4 (LTD4) evoked increases in the cytosolic concentration of intracellular calcium ([Ca+2]i) in dimethylsulfoxide-differentiated HL-60 cells, as assessed by the fluorescence of ...
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