LINEAGE-COMMITMENT
Long non-coding RNA HoxA-AS3 interacts with EZH2 to regulate lineage commitment of mesenchymal stem cells
... Long non-coding RNAs (lncRNAs) play an important role in gene regulation and are involving in diverse cellular processes. However, their roles in reprogramming of gene expression profiles during lineage ...
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Geminin cooperates with Polycomb to restrain multi lineage commitment in the early embryo
... We previously defined Geminin (Gem or Gmnn) as another putative cell intrinsic regulator of early embryogenesis. Geminin is a small predominantly nuclear protein that can promote neural gene expression at the expense of ...
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c-Maf regulates pluripotency genes, proliferation/self-renewal, and lineage commitment in ROS-mediated senescence of human mesenchymal stem cells
... c-Maf is a large Maf TF[12] and involves in a number of developmental processes, including immune cellular differentiation [18, 29] and ocular lens development [30, 31]. In addition, reduction of c-Maf has been reported ...
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Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis
... and Supplemental Table 2) preferentially enriched at gene promot- ers (Supplemental Figure 7B). KDM2B binds a core of 780 genes in all cell lines as well as distinct, cell-type–specific gene sets (Figure 9A). IPA of the ...
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Developmental fate and lineage commitment of singled mouse blastomeres
... To visualize these data, we employed principal component analysis (PCA) based on the expression of these genes in the TE, ICM and 1/32LS blastomeres. Projection of the blastomere expression patterns onto component 1 and ...
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Numb regulates somatic cell lineage commitment during early gonadogenesis in mice
... During early gonadogenesis, proliferating cells in the coelomic epithelium (CE) give rise to most of the somatic cells in both XX and XY gonads. Previous dye-labeling experiments showed that a single CE cell could give ...
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Mammary development in the embryo and adult: a journey of morphogenesis and commitment
... and lineage commitment events that occur during all three stages of mouse mammary gland ...lymphocyte lineage decisions, in mammary epithelial lineage ...
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Fas Receptor Modulates Lineage Commitment and Stemness of Mouse Neural Stem Cells
... Figure 5. LPR NPCs have enhanced differentiation into Neuronal and OPC lineages. (a) Representative fluorescence histo- gram for A2B5 positivity after 2 days in minimal media (red = isotype control [ISO]); (b) ...
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Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment
... (Arney et al., 2002; Probst et al., 2007; Puschendorf et al., 2008; Santos et al., 2005). This differential loading of Ring1B and Suv39h onto heterochromatin underlies parental genome asymmetry in the zygote and is ...
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Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and β catenin signaling
... Growth factor signaling provides another layer of Yap/ β -catenin- mediated control over branching and differentiation programs, as Fgf10/Kras and Fgf10/ β -catenin signaling induce the expression of the branching ...
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FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self renewal to lineage commitment
... and lineage commitment during continuous ...differentiation. Lineage commitment potential of Fgf4-null cells is restored by provision of FGF ...potentiates lineage commitment ...
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FOXF1 inhibits hematopoietic lineage commitment during early mesoderm specification
... the lineage specification of early mesodermal precursors expressing or not the Forkhead transcription factor ...increased commitment toward primitive erythropoiesis in Foxf1-deficient embryos, whereas ...
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Side branching and luminal lineage commitment by ID2 in developing mammary glands
... There are four different forms of Inhibitor of DNA-binding (ID) protein: ID1, ID2, ID3 and ID4. Although they all have a helix-loop- helix (HLH) domain (Norton et al., 1998), their respective functions in mammary glands ...
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Biophysical Regulation of Stem Cell Osteogenic Lineage Commitment: A Role for the Cytoskeleton
... osteogenic lineage commitment (Liu, 2010, Liu et ...osteogenic lineage commitment of hMSCs, but surprisingly ECM deposition is magnitude ...
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Psychological Contract, Organizational Commitment and Work Satisfaction: Survey of Researchers in Chinese State Owned Engineering Research Institutions
... zational commitment influences the effect of knowledge workers’ psychological contract on work ...organizational commitment plays partially a mediating effect on the link between psychological contract and ...
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STUDY OF PROFESSIONAL COMMITMENT AMONG P S E B AND C B S E SECONDARY SCHOOL TEACHERS IN RELATION TO THEIR TEACHING EXPERIENCE
... professional commitment of teacher educators serving in secondary teacher training institutions of Himachal ...Professional Commitment of Teacher Educators from 135 teacher educators of 25 ...professional ...
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A review to understand relationship marketing and customer loyalty: effect factors
... Customer loyalty: Although the term brand loyalty and customer loyalty has been assimilated consciously or unconsciously in various studies (Srinivasan et al., 2002; Yang and Peterson, 2004), but are two different ...
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A GUIDE FOR LANDLORDS
... A number of landlords have asked whether they can sign as part of a consortia (eg where a number of housing associations operating in an area want to make a joint commitment). This approach may be appropriate in ...
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Assessing crossnational invariance of the three component model of organizational commitment:A cross country study of university faculty
... organizational commitment of the workers in ...organizational commitment (Akintayo, ...normative commitment and low workers’ continuance commitment (Ahiauzu & Asawo, ...organizational ...
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STUDY ON PROFESSIONAL COMMITMENT OF MATRICULATION SCHOOL TEACHERS IN VIRUDHUNAGAR DISTRICT
... of commitment to basic human ...professional commitment of the teachers working in Matriculation ...professional commitment of Matriculation School teachers, and suggest measures to enhance their ...
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