LINING FLUID
Continuous monitoring of the bronchial epithelial lining fluid by microdialysis
... Microdialysis is a method for continuous sampling of extracellular molecules in the immediate surroundings of the catheter. The technique is based on the principle of diffusion of substances along a concentration ...
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Relationship between Cytomegalovirus DNA Load in Epithelial Lining Fluid and Plasma of Lung Transplant Recipients and Analysis of Coinfection with Epstein Barr Virus and Human Herpesvirus 6 in the Lung Compartment
... Herpesvirus infections are a considerable burden and pose a challenge to the management of organ transplant recipients (16). Among herpesvirus infections, cytomegalovirus (CMV) infection is one of the most severe ...
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Structure-based prediction of anti-infective drug concentrations in the human lung epithelial lining fluid
... Hospital- or ventilator acquired pneumonia (HAP, VAP) is associated with a high mortality (1). Therefore, reaching effi- cacious effect-site concentrations of antibiotics is essential for successful treatment (2) and to ...
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KL-6 concentration in pulmonary epithelial lining fluid is a useful prognostic indicator in patients with acute respiratory distress syndrome
... the S-S bond near the surface of the epithelial cell mem- brane, KL-6 can diffuse into pulmonary epithelial lining fluid (ELF). In the normal lung, this glycoprotein can be predominantly found on alveolar ...
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Anti-staphylococcal activity resulting from epithelial lining fluid (ELF) concentrations of amikacin inhale administered via the pulmonary drug delivery system
... epithelial lining fluid; IV: intravenous; PK: pharmacokinetics; PD: pharmacodynamics; PDDS: pulmonary drug delivery system; MIC: minimum inhibitory concentration; MRSA: methicillin- resistant Staphylococcus ...
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Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: two protective CFTR-dependent thiols against oxidative injury
... Cystic fibrosis (CF) can result in impaired pulmonary function from defects in mucus clearance resulting in chronic infections and inflammation. CF is caused by a mutation in the cystic fibrosis transmembrane regulator ...
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Napsin A levels in epithelial lining fluid as a diagnostic biomarker of primary lung adenocarcinoma
... epithelial lining fluid (ELF), the liquid which covers the bronchial wall and alveolus, without the need for saline injection ...lavage fluid [11, ...
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Antioxidant macromolecules in the epithelial lining fluid of the normal human lower respiratory tract
... We hypothesized that the alveolar structures may contain extracellular macromolecules with antioxidant properties to defend against oxidants. To evaluate this 51Cr-labeled human lung fibroblasts (HFL-1) and cat lung ...
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Kerbs von Lungren 6 antigen is a marker of alveolar inflammation but not of infection in patients with acute respiratory distress syndrome
... oedema fluid early in the course of ARDS ...epithelial lining fluid levels were elevated in nonsurvivors and alveolar epithe- lial type II cell production of KL-6 was shown to be cytokine ...
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Protein corona: implications for nanoparticle interactions with pulmonary cells
... lung lining fluid forming the NP corona, and their role in regulating translocation of NPs across the air blood barrier and in determining which cells bind and/or in- gest NPs, are ...
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Natural killer cells are present in the normal human lung but are functionally impotent
... epithelial lining fluid exerted a profound suppressive effect on blood NK cell activity (P less than 0.001 for both) by inhibiting their ability to lyse target cells after binding (P less than 0.001). ...
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The particle has landed characterizing the fate of inhaled pharmaceuticals
... the lining fluid thins to 1 m m or less and has a more Newtonian ...this fluid layer provides a lim- ited sink capacity for dissolution yet little resistance to dif- fusion, unless drugs and ...
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Modulation of airway inflammation in cystic fibrosis In vivo suppression of interleukin 8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor
... Based on the knowledge that neutrophil elastase (NE) in cystic fibrosis (CF) epithelial lining fluid (ELF) can induce human bronchial epithelial cells to express the gene for interleukin 8 (IL-8), an 8.5-kD ...
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Modelling processes in tubular rotary kiln for creating control systems for sintering processes
... The lining of a TRK plays an important role in the implementation of the basic technological functions of the TRK and ensuring its economical ...the lining operation at the selected compliance level depends ...
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The Permeability of the Cuticular Lining of the Insect Alimentary Canal
... Interestingly, the permeability of the cuticular lining of the colon was also low, about 15 times lower than the cuticle lining either the ileum, which lies anterior to it, or the rectum[r] ...
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Characterization of histopathology and gene expression profiles of synovitis in early rheumatoid arthritis using targeted biopsy specimens
... the lining tissues, in studies using microdissected rheumatoid synovial ...tilayered lining in group I, which fails to induce CASP9 and PIG11, while wild-type p53 in group II may induce these genes in group ...
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Comparative Study and Analysis of brake shoe lining using Composite Material by Ansys14
... Thermal analysis follows the similar steps followed in the static structural analysis. The major difference is that it takes into consideration the heat flow in it. Similarly in the engineering model option, the new ...
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Pore-Lining Residues and Intracellular Magnesium Concentration Influence Connexin50 Gap Junction Unitary Channel Conductance
... underlying molecular determinants are not fully clear. The amino terminal (NT), first transmembrane and first extracellular domain (M1-E1) border of several connexins are proposed to line the pore and are implicated to ...
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Structure, material characteristics and function of the upper respiratory tract of the pygmy sperm whale
... vascular lining should not pose significant DCS problems: the luminal surface area of the lining is relatively low, limiting gaseous exchange, while blood flow through the lining during dives is ...
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Fibroblast biology Signals targeting the synovial fibroblast in arthritis
... It has been claimed that the rheumatoid arthritis synovial fibroblasts differ from their nonrheumatoid counterparts in terms of growth rate, life span, glycolytic metabolism, syn- thesis of hyaluronan and sulfated ...
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