Lipid Binding
Characterization of the relationship between the chaperone and lipid-binding functions of the 70-kDa heat-shock protein, HspA1A
... the lipid bilayer results in oligomerization of the protein [8,21,22] , which by changing the quaternary structure of the complex could further support the conformational change ...either binding to or ...
28
Lipid binding attenuates channel closure of the outer membrane protein OmpF
... the lipid headgroup-binding ...the lipid head- groups in a lipid ...the lipid headgroup-binding region than α -helical membrane proteins (gray ...outside lipid ...
7
Investigation of the Lipid Binding Properties of the Marburg Virus Matrix Protein VP40
... purported lipid binding surface or the basic patch of the ...construct binding to vesicles containing PS was ⬃ 30% reduced while binding of double and triple mutations of the mVP40 cationic ...
12
Function and interactions of the Ysc84/SH3yl1 family of actin- and lipid-binding proteins
... classes of invertebrates including, insecta, mollusca and echinodermata. This domain is also found in plants (e.g Arabidopsis thaliana and Oryza sativa) but in this case it is found most often at the C-terminus of ...
13
Characterization of the Relationship between the Chaperone and Lipid-Binding Functions of the 70-Kda Heat-Shock Protein, HspA1A
... is lipid-driven, it is imperative to characterize the lipid-binding regions of HspA1A and the relationship between the chaperone and lipid-binding functions of HspA1A, which remain ...
11
The role of pH, self-association, and lipid binding in vinculin tail structure and function
... The lipid binding function of vinculin is localized to the tail domain (Vt), which had been reported to bind to acidic phospholipids, including PS, PI, and PIP 2 [20, ...
111
Protein-lipid interactions: correlation of a predictive algorithm for lipid-binding sites with three-dimensional structural data
... in lipid binding by our algorithm, amino acid resi- dues 935–978 and 1020–1040, contribute to helices 2 through 5 of ...2 binding by ...predicted lipid-binding site, is essential for ...
14
Analysis of Epichloë festucae membrane lipid composition and its role in Nox complex assembly : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University, Palmerston North, New Zealand
... The lipid-binding PH domain of Nox protein Cdc24 was found to be necessary for membrane localisation, supporting a role for lipid signalling in fungal Nox complex regulation.. To identif[r] ...
21
Efficacy of Over the Counter (OTC) Medical Device Products as a Tool in Clinical Weight Management
... from lipid binding analysis. The much lower lipid binding capacity observed for the two vegetal opuntia-derived samples may be the result in a varia- tion in the raw active ingredient or ...
8
Oxidative Stress, a-Synuclein, and Apoptosis in Parkinson’s Disease
... pathway, lipid binding, and dopamine transport all provide hypotheses for its involvement with oxidative stress conditions that may cause the neuronal degeneration seen in ...
7
The Interaction of ApoA-I and ABCA1 Triggers Signal Transduction Pathways to Mediate Efflux of Cellular Lipids
... apoA-I binding to the cell surface ...for binding of apoA-I and lipid ...apoA-I/ lipid interactions functions in the assem- bly of nascent HDL particles ...apoA-I binding on the ABCA1 ...
10
Animal cell cytokinesis : the role of dynamic changes in the plasma membrane proteome and lipidome
... of lipid-based control of membrane protein function is well-established; recent work has identified lipid binding domains that can regulate membrane trafficking via direct interaction with coat ...
29
Spira, Felix (2012): Spatio-temporal organisation of plasma membrane proteins in budding yeast. Dissertation, LMU München: Fakultät für Biologie
... The lipid shell hypothesis assumes that proteins are surrounded by static layers of lipids, which drives similar proteins into larger domains (Anderson and Jacobson, ...This lipid or wetting film prevents ...
183
The role of species specific modifications in peptidoglycan biosynthesis
... ligand binding led to a conformational change resulting in an ‘open’ active site (Macheboeuf et ...allosteric binding domain 60 Å away from the transpeptidase active site, which could be activated by ...
391
Membrane potential-dependent binding of polysialic acid to lipid monolayers and bilayers
... the binding of the peptide hormone angiotensin to renal epithelial cells [7], the action of G-protein coupled receptors [8], the dynamics of dolichyl phosphate in membranes [9], and cardiac excitation-contraction ...
16
Inhibition of HIV Replication by Apolipoprotein A I Binding Protein Targeting the Lipid Rafts
... and lipid raft abundance induced by exosomes produced by cells transfected with empty vector and the effects induced by vector expressing green fluorescent protein (GFP) (used as a control in the previous study) ...
20
Dynamin- and Lipid Raft-Dependent Entry of Decay-Accelerating Factor (DAF)-Binding and Non-DAF-Binding Coxsackieviruses into Nonpolarized Cells
... In this study we combined an Ang-2–neutralizing monoclonal antibody that targets both human and murine Ang-2, MEDI3617 MedImmune 34, with cediranib AstraZeneca Pharmaceuticals and assess[r] ...
6
Draft genome of the scabies mite
... The predicted proteome of S. scabiei was relatively small compared to the other available annotated Acari genomes, and contained 10,644 proteins (Table 2). The largest predicted protein-coding gene was 34 kb in length ...
14
Relationship of oxygen and glutathione in protection against carbon tetrachloride induced hepatic microsomal lipid peroxidation and covalent binding in the rat Rationale for the use of hyperbaric oxygen to treat carbon tetrachloride ingestion
... tension. Lipid peroxidation and covalent binding of 14C fell progressively as O2 tension was increased from 1 to ...both lipid peroxidation and covalent ...
7
Unconventional Secretion of AcbA in Dictyostelium discoideum through a Vesicular Intermediate
... Acyl-CoA binding proteins (ACBPs) are small, highly con- served proteins that are found in all ...shuttles lipid intermediates around the cell but also serves as a precursor of DBI, a peptide that functions ...
9