lncRNA H19
LncRNA H19 promotes triple-negative breast cancer cells invasion and metastasis through the p53/TNFAIP8 pathway
... of lncRNA H19 in regulating EMT-MET pro- cess ...that lncRNA H19 promotes EMT by downregulating E-cadherin through diverse molecular mechanisms, such as stimulat- ing the Wnt/β-catenin ...
14
Association of genetic variants in lncRNA H19 with risk of colorectal cancer in a Chinese population
... of H19 ascribed to selected SNPs using RNAfold and SNPfold ...of H19 and exerting various effects on H19 expression and function ...of H19 due to rs2839689 variant, which ultimately modulate ...
8
Association of lncRNA H19 rs217727 polymorphism and cancer risk in the Chinese population: a meta-analysis
... LncRNA H19, as an imprinted gene, servers as an oncogene and was aberrantly increased in several cancers, and it might promote carcinogenesis via acting as competitive endogenous RNAs (ceRNA) or precursors ...
9
LncRNA H19 over-expression inhibited Th17 cell differentiation to relieve endometriosis through miR-342-3p/IER3 pathway
... 13]. LncRNA H19 is one of the most widely studied LncRNAs in cancers, angiogenesis, diabetes mellitus, ...2010, H19 was firstly detected in women with EMS and found lower expression in endometrial ...
10
Original Article Upregulated lncRNA H19 promotes non-small cell lung cancer cell proliferation through miR-138/PDK1 axis
... (lncRNA) H19 was reported to be aberrantly expressed and implicated in non-small cell lung cancer ...by H19 was not well ...of H19 was obviously increased, but miR-138 was decreased in NSCLC ...
9
Original Article LncRNA H19 promotes proliferation and invasion in A375 human melanoma cell line
... (lncRNA) H19 and its par- ticipation in the migration pro- cess of cancer ...study, H19 was chosen as a novel biological marker to explore its roles in the prolif- eration and invasion of me- ...
11
Knockdown of LncRNA H19 Relieves LPS Induced Damage by Modulating miR 130a in Osteoarthritis
... of lncRNA H19 and miR-130a in LPS- damaged C28/I2 cells, the expression levels of H19 and miR-130a were measured by reverse-transcription quantitative PCR (RT- qPCR) ...of lncRNA H19 or ...
8
The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer
... identified lncRNA H19 as a novel player in modulating EMT progress and revealed a previously unknown mechanism involving H19 and EMT-related miRNAs in cancer ...that H19 promoted EMT revealed ...
13
Original Article Roles of lncRNA H19 and MALAT1 as biomarkers in patients with white-coat hypertension
... MALAT1 lncRNA has not yet been studied in HT or ...of lncRNA H19 and MALAT1 in the PMBCs of patients with elevated BP, and to establish them as novel potential noninvasive biomarkers for differenti- ...
10
Original Article Regulation and mechanisms of lncRNA H19 in COPD
... of lncRNA H19 in COPD rats improved lung tissue struc- ture, downregulated secretion of inflammatory factors IL-6, IL-8, and TNF-α, upregulated SOD activity, and inhibited ROS generation, suggest- ing that ...
8
LncRNA H19 confers chemoresistance in ERα-positive breast cancer through epigenetic silencing of the pro-apoptotic gene BIK
... the lncRNA H19 is one of the downstream molecules of ERα in breast cancer cells, and that upregulation of H19 by ERα modulates the apoptosis response to chemotherapy in breast cancer ...
11
Functional polymorphisms of the lncRNA H19 promoter region contribute to the cancer risk and clinical outcomes in advanced colorectal cancer
... ered lncRNA, H19 is involved in regulating gene expres- sion in the imprinted gene network and contributes to growth control in development [19, ...of H19 and then develop the cancer ...
12
LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy
... SE. H19 overexpression alone increased p-Stat3 and c-Myc protein levels in the CA3 subfield of the hippocampus ...5c). H19 exacerbated these protein expressions in the rats at 7 days ...contrary, H19 ...
9
Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19
... of H19, stemness and oxaliplatin resistance of colorectal cancer cells To assess whether CAFs regulate the CSC-like characteristics of CRC cells, we treated human CRC cells with conditioned medium derived from NFs ...
17
LncRNA H19 promotes the differentiation of bovine skeletal muscle satellite cells by suppressing Sirt1/FoxO1
... well-characterized lncRNA in mammalian ...[8]. H19 functions as a post-transcriptional suppressor or miRNA sponge for let-7, helping to regulate the Igf2 signaling pathway [9, ...
10
<p>Metformin Suppresses the Proliferation and Promotes the Apoptosis of Colon Cancer Cells Through Inhibiting the Expression of Long Noncoding RNA-UCA1</p>
... that lncRNA-urothelial carcinoma- associated 1 (UCA1) plays a critical role in tumorigenesis, such as that of laryngeal squamous cell carcinoma, 14 lung adenocarcinoma 15 and colon ...the lncRNA-H19 ...
13
Original Article The long non-coding RNA H19 promotes invasion and metastasis of ovarian cancer cell through EMT-related protein regulation
... (lncRNA) H19 is reported to be involved in invasion and metastasis of ovarian cancer ...whether lncRNA H19 involvement in OC invasion and metastasis is associated with EMT remains ...of ...
9
Long noncoding RNA H19 upregulates vascular endothelial growth factor A to enhance mesenchymal stem cells survival and angiogenic capacity by inhibiting miR-199a-5p
... between lncRNA–miRNA functional networks has drawn much attention in recent years ...[35]. LncRNA-H19 can function as a primary miRNA tran- script or as a miRNA sponge [36, ...of ...
12
Associations between polymorphisms of long non-coding RNA MEG3 and risk of colorectal cancer in Chinese
... between lncRNA H19 and gastric cancer; they found an important role for H19 variants in gastric cancer carcinogenesis ...on lncRNA HOTAIR expression, as well as associated with the development ...
6
<p>Long non-coding RNA H19 promotes the proliferation and invasion of lung cancer cells and regulates the expression of E-cadherin, N-cadherin, and vimentin</p>
... shLncRNA H19 NC or LncRNA H19 NC exerted a negligible effect on the viability, cell number, and rate of colony formation of A549 ...shLncRNA H19 significantly decreased the viability, cell ...
9