lncRNA XIST
Original Article lncRNA XIST promotes aggressive tumor phenotype and is associated with poor prognosis in esophageal squamous cell carcinoma
... of lncRNA XIST was significantly associat- ed with poor prognosis and was an indepen- dent prognostic factor in ...ESCC. lncRNA XIST is an important inhibitor of X chromosome inacti- vation ...
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<p>TCF-4 Regulated lncRNA-XIST Promotes M2 Polarization Of Macrophages And Is Associated With Lung Cancer</p>
... of lncRNA XIST played in the regulation of macrophage ...of lncRNA XIST compared to ...of lncRNA XIST in macrophages by directly targeting promoter region of XIST gene and ...
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Original Article The lncRNA XIST regulates the tumorigenicity of renal cell carcinoma cells via the miR-302c/SDC1 axis
... of lncRNA-XIST in the tumorigenicity of renal cell carcinoma (RCC) cells via the miR-302c/SDC1 ...and XIST in RCC tissues and cells were analyzed by ...between XIST and miR-302c was analyzed ...
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LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells
... (EMT). LncRNA X inactive specific transcript (XIST) is highly expressed in tumour tissues, promotes cancer progression and might act as an miRNA molecular ...between lncRNA XIST and miR-200c ...
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Up-regulated lncRNA XIST contributes to progression of cervical cancer via regulating miR-140-5p and ORC1
... and XIST could offset the effect of si-ORC1 ...5 LncRNA XIST directly interacted with ...g XIST expression in Hela and C3AA cells was no change when the cells were transfected with miR-140-5p ...
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Original Article Knockdown of lncRNA XIST suppresses osteosarcoma progression by inactivating AKT/mTOR signaling pathway by sponging miR-375-3p
... Methods: lncRNA XIST, miRNA expression were detected by ...between lncRNA, miRNA and ...Results: XIST expression was up- regulated but miR-375-3p was down-regulated in OS tissues and ...of ...
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Original Article LncRNA XIST, as a ceRNA of miR-204, aggravates lipopolysaccharide-induced acute respiratory distress syndrome in mice by upregulating IRF2
... miRNAs can lead to transla- tion repression or RNA degra- dation by binding to the 3’UTR of target mRNA [32]. In various studies, it has been confirm- ed that miRNAs play a role in numerous physiologic process- es, ...
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<p>LncRNA XIST Promotes Growth of Human Chordoma Cells by Regulating miR-124-3p/iASPP Pathway</p>
... between lncRNA XIST and miR-124-3p, we posited that lncRNA XIST was involved in regulating ...of lncRNA XIST in chordoma, we established knockdown and overexpression models of ...
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lncRNA XIST regulates proliferation and migration of hepatocellular carcinoma cells by acting as miR-497-5p molecular sponge and targeting PDCD4
... of XIST-WT, but not XIST-MUT, in Huh7 and HepG2 cells ...that lncRNA XIST was significantly downregulated in the 77 HCC tissues compared with the matched adjacent normal tissues ...and ...
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<p>LncRNA XIST depletion prevents cancer progression in invasive pituitary neuroendocrine tumor by inhibiting bFGF via upregulation of microRNA-424-5p</p>
... that XIST over-expres- sion promoted non-small cell lung cancer (NSCLC) cell via- bility and invasion in vitro, while XIST silencing suppressed NSCLC cell activities in ...of lncRNA XIST could ...
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LncRNA XIST/miR-34a axis modulates the cell proliferation and tumor growth of thyroid cancer through MET-PI3K-AKT signaling
... A total of 30 eight-week-old athymic female nude mice with an average weight of 20 g were obtained from The Jackson Laboratory (Bar Harbor, ME USA), and anesthetized with an intraperitoneal injection of 2% ...
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<p>Knockdown of lncRNA XIST Suppresses Cell Tumorigenicity in Human Non-Small Cell Lung Cancer by Regulating miR-142-5p/PAX6 Axis</p>
... which XIST were implicated in NSCLC pathogenesis, the potential miRNA targets of XIST were predicted using StarBase program and we found miR-142-5p had binding sites with XIST (Figure ...the ...
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Prognostic role of long non-coding RNA XIST expression in patients with solid tumors: a meta-analysis
... of lncRNA XIST suppressed cells prolif- eration, migration and invasion in vitro as well as tumo- rigenesis and metastasis in vivo in GC (2016) and ESCC (2017), ...between lncRNA XIST and ...
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Original Article Long non-coding RNA Xist promotes progression of non-small-cell lung cancer (NSCLC) by modulating miR-103a and MAP3K3 pathway
... miRNA precursors were purchased from Am- bion (Austin, TX). Synthetic miR-103a mimic and scrambled negative control RNA were pur- chased from Genepharma (Shanghai, China). Cells were seeded in 6-well plates and were ...
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Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression
... of lncRNA XIST in gastric cancer ...of lncRNA XIST in gastric cancer cells (*P < ...of lncRNA XIST significantly inhibited cell proliferation in SGC7901 and AGS ...whether ...
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Original Article Long non-coding RNA XIST promotes cervical cancer cell epithelial-mesenchymal transition through the Wnt/β-catenin pathway
... of lncRNA MALAT1 correlated with tumor progression and poor prognosis in clear cell renal cell carcinoma ...of lncRNA GAS5 indicated a poor prognosis and promoted cell proliferation in gastric cancer ...of ...
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miR-34a-mediated regulation of XIST in female cells under inflammation
... of XIST could affect the sites it coats on the inactive X ...in XIST levels and localization under acute and chronic inflammation are needed to validate ...of XIST in acute inflammation and chronic ...
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Long non coding XIST raises methylation of TIMP 3 promoter to regulate collagen degradation in osteoarthritic chondrocytes after tibial plateau fracture
... example, lncRNA X-inactive specific transcript (lncRNA XIST), a member of the first discovered cancer-related lncRNAs, has been implicated in the progression of mul- tiple types of tumors ...of ...
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Long noncoding RNA <em>XIST </em>promotes proliferation and invasion by targeting miR-141 in papillary thyroid carcinoma
... of XIST in PTC, we knocked down the expression of the lncRNA XIST using a specific siRNA (si-XIST), while using a nonsilencing siRNA (si-NC) as the negative ...decreased XIST expression ...
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XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way
... Long non-coding RNAs (lncRNAs) are a class of non- coding RNA molecules that are more than 200 nucleo- tides in length and do not encode proteins [7]. They are involved in many biological processes, such as participa- ...
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