Long Non-Coding RNAs
Identification of novel long non-coding RNAs in triple-negative breast cancer
... Long non-coding RNAs (lncRNAs) are a subclass of noncoding RNAs (ncRNAs) and have sequence lengths of 200 bp and above [2, 3]. It has become increasingly apparent that lncRNAs ...
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An overview of long non-coding RNAs in ovarian cancers
... into non- coding RNAs ...of long non-coding RNAs (lncRNAs) has come to ...endogenous RNAs [13, 14] or by hosting miRNAs [15, ...
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Long non-coding rnas – “tuning fork” in regulation of cell processes
... these RNAs are denoted as long non-coding RNAs (lncRNAs) which function as signaling mol- ecules, navigating systems and platforms for ribonu- cleic complexes ...
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Emerging role of long non-coding RNAs in cisplatin resistance
... lncRNAs, long non-coding RNAs; LSCC, lung squamous cell carcinoma; MDR1, multidrug-resistant protein; MRP1, multidrug-resistant-associated protein 1; N/A, not available; NEAT1, ...
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Ribosome profiling reveals resemblance between long non coding RNAs and 5′ leaders of coding RNAs
... Long non-coding RNAs (lncRNAs) have emerged as important regulators of gene expression during development (Pauli et al., 2011; Rinn and Chang, 2012). lncRNAs were initially discovered for ...
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Roles of Long non coding RNAs in Cellular Stress Response
... Cellular systems are often exposed to variations in their environment and, as a consequence, the cell systems have evolved a variety of pathways to promote cell survival during such challenges. Such “pro-survival” ...
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Long non-coding RNAs as prognostic markers in human breast cancer
... Long non-coding RNAs (lncRNAs) have been recently shown to play an important role in gene regulation and normal cellular functions, and disease ...
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Long non coding RNAs and enhancer RNAs regulate the lipopolysaccharide induced inflammatory response in human monocytes
... both coding and non-coding regions of the ...of non-coding RNAs, which display both tissue- and developmental time point-specific transcription 6,7,9 ...of ...
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Expressions of Long Non Coding RNAs in Carcinogenesis of Cervix: A Review
... Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleo- tides mostly transcribed by RNA which do not encode proteins. Previously, lncRNAs were considered transcriptional ...
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Uncovering the roles of long non-coding RNAs in cancer stem cells
... recurrence. Long non-coding RNAs refer to a class of RNAs that are longer than 200 nt and have no potential to code proteins, some of which can be specifically expressed in different ...
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<p>Advances with Long Non-Coding RNAs in Diabetic Peripheral Neuropathy</p>
... Abstract: Long non-coding RNAs (lncRNAs) are a group of non-coding RNAs longer than 200 nucleotides, which are de fi ned as ...
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The functional role of long non-coding RNAs and epigenetics
... many RNAs do not code for proteins in eukary- otes. There are RNAs that lack an apparent open reading frame (ORF) of 300 nt or ...noncoding RNAs [1-3]. Long non-coding ...
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The Role of Long Non-Coding RNAs in Ovarian Cancer
... Background: Ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. Various studies have already identified suitable ...
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Long non coding RNAs (lncRNAs) are dysregulated in Malignant Pleural Mesothelioma (MPM)
... a long latency period (20–40 years between initial exposure and diagnosis) and prior exposure to ...of long non-coding RNAs (lncRNAs) play an important functional role in cancer ...
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Emerging Roles of Long Non-Coding RNAs as Drivers of Brain Evolution
... of non-coding RNAs (ncRNA) have been identified. Non-coding RNAs are distinguished in small and long non- coding RNAs (scnRNAs and lncRNAs, ...
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The Role of Long Non Coding RNAs in the Repair of DNA Double Strand Breaks
... classic non coding RNAs such as ribosomal (r)RNAs, ribozymes, transfer (t)RNAs and microRNAs ...These long non coding RNAs (lncRNAs) are major participants ...
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Antisense Long Non-Coding RNAs Are Deregulated in Skin Tissue of Patients with Systemic Sclerosis
... protein coding genes and pathways that are differently regulated in SSc and, as a consequence, are missing an important component of non-coding genes involved in disease path- ...the non- ...
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The Roles and Diagnostic Potential of Long Non-Coding RNAs in Some Cancers: A Review
... noncoding RNAs (ncRNAs) are indeed crucial molecules with diverse roles in ...cancers. Long non-coding RNAs (lncRNAs) are a group of ncRNAs composed of >200 nucleotides that play ...
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Long non-coding RNAs in the regulation of myeloid cells
... Enhancer RNAs; G-MDSCs: Granulocytic myeloid-derived suppressor cells; H3K27ac: Histone H3-lysine-27 acetylation; H3K4me3: Histone H3-lysine- 4 trimethylation; HAT: Histone acetyltransferase; HOTAIR: HOX antisense ...
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<p>Long Non-Coding RNAs in Drug Resistance of Breast Cancer</p>
... therapies. Long non-coding RNAs (lncRNAs) are involved in drug resistance in BC via various mechanisms, which contribute to a complex regulatory ...
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