lopinavir/ritonavir
Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon β1b (MIRACLE trial): statistical analysis plan for a recursive two stage group sequential randomized controlled trial
... of Lopinavir/ritonavir and intErferon- β 1b) investigates the efficacy of a combination therapy of lopinavir/ritonavir and recombinant interferon- β 1b provided with standard supportive care, ...
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Long-term Follow-up of 414 HIV-Infected Romanian Children and Adolescents Receiving Lopinavir/Ritonavir-Containing Highly Active Antiretroviral Therapy
... with lopinavir/ritonavir was interrupted on 312 occa- sions in 220 ...to lopinavir/ritonavir therapy were observed, consisting principally of intractable vomiting (11 episodes) and hepatitis ...
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The interaction between artemether lumefantrine and lopinavir/ritonavir based antiretroviral therapy in HIV 1 infected patients
... the lopinavir group compared to the ARV-naïve group at 0 to 8 h, although these were similar between treatment groups after the last ...the lopinavir group at 0 – 8 hours, which was also reported by German ...
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Treatment of Middle East Respiratory Syndrome with a combination of lopinavir ritonavir and interferon β1b (MIRACLE trial): study protocol for a randomized controlled trial
... taking lopinavir/ ritonavir-containing antiretroviral regimens ...to lopinavir/ritonavir occurs, but is rare, with symp- toms or jaundice appear usually after 1 to 8 weeks of starting therapy ...
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Novel strategies in the use of lopinavir/ritonavir for the treatment of HIV infection in children
... Abstract: Lopinavir/ritonavir (LPV/r) is considered by many as the first choice protease inhibitor (PI) for ...take ritonavir separately to “boost” the levels of ...of ritonavir), difficult ...
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Lopinavir/Ritonavir versus Lamivudine peri exposure prophylaxis to prevent HIV 1 transmission by breastfeeding: the PROMISE PEP trial Protocol ANRS 12174
... treatment. Lopinavir/ritonavir (LPV/r) is an attractive PEP candidate with presumably higher efficacy against HIV than nevirapine or lamivudine, and a higher genetic barrier to resistance ...
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Lopinavir/ritonavir: is early administration better in Covid-19?
... plus ritonavir combination is readily available in the market and is used in the treatment regimen of Human immunodeficiency virus (HIV) ...patients. Lopinavir is an HIV protease inhibitor that prevents the ...
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Formulation preference, tolerability and quality of life assessment following a switch from lopinavir/ritonavir soft gel capsule to tablet in human immunodeficiency virus-infected patients
... Lopinavir/ritonavir (LPV/r) tablet is now widely used in combination with other antiretroviral agents in place of the soft gel capsule (SGC) in the treatment of HIV-infec- tion. Developed by the melt ...
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ANALYTICAL METHODS DEVELOPMENT & VALIDATION FOR SIMULTANEOUS ESTIMATION OF LOPINAVIR & RITONAVIR IN PHARMACEUTICAL FORMULATION BY SIMULTANEOUS EQUATION METHOD USING UV SPECTROPHOTOMETRY
... of Lopinavir and Ritonavir in bulk and pharmaceutical dosage form using the UV ...of Lopinavir and Ritonavir were found ...for Lopinavir and 10-60 µg/ml of Ritonavir Coefficient ...
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Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy
... Previous studies of the pharmacokinetic interaction of rifabutin with LPV/r in HIV infected individuals have mostly been small case series or involved an adaptive de- sign in which only selected patients were exposed to ...
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Significant improvements in self-reported gastrointestinal tolerability, quality of life, patient satisfaction, and adherence with lopinavir/ritonavir tablet formulation compared with soft gel capsules
... In this study, we report the results of a mar- ket research survey, which was designed to assess the dif- ferences in tolerability benefits, patient satisfaction, changes in adherence, a[r] ...
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NEW SENSITIVE UV SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF LOPINAVIR AND RITONAVIR IN FIXED DOSE COMBINATION AS SOFT GELS
... Hyderabad), Ritonavir (Hetero Labs, Hyderabad) were procured as gift ...Lopinavi+50mg Ritonavir( Lopinavir/Ritonavir contains;200mg/50mg) and their respective working standards were prepared ...
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Repurposing antivirals as potential treatments for SARS-CoV-2: From SARS to COVID-19
... 2015). Lopinavir/ritonavir is an inhibitor of HIV-1 protease that causes an antiviral effect on the maturation of virions ...using lopinavir and lopinavir/ritonavir with ribavirin have ...
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Selection of Resistance in Protease Inhibitor-Experienced, Human Immunodeficiency Virus Type 1-Infected Subjects Failing Lopinavir- and Ritonavir-Based Therapy: Mutation Patterns and Baseline Correlates
... to lopinavir was characterized by analyzing the longitudinal isolates from 54 protease inhibitor-experienced subjects who either experienced incomplete virologic response or viral rebound subsequent to initial ...
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COVID-19: the Prognosis, Mortality, Medications, and Possible Vaccines
... chloroquine, lopinavir/ritonavir, hydroxychloroquine, and lopinavir/ritonavir combined with interferon beta; as of May 2020, there is tentative evidence for remdesivir ...
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PubMedCentral-PMC5036919.pdf
... The International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT) P1060 trial was designed to assess the safety and efficacy of 2 ART regimens for children <3 years of age with and without prior ...
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A COMPARATIVE STUDY ON THE ASSESSMENT OF RISKY LIPID PROFILES AMONG TWO RETROVIRAL THERAPEUTIC STRATEGIES
... i.e. lopinavir/ritonavir and nevirapine at doses recommended by the ...of lopinavir/ritonavir and nevirapine groups were diagnosed with advanced and progressive disease (CD4 cell count ...
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“Potential Anti-COVID-19 Drug Options” by P. Ravi Sankar, A. Viswanath, K. Supriya, India.
... drugs, lopinavir and ritonavir, lopinavir, and ritonavir plus interferon beta and the antimalarial drug chloroquine and Hydroxy ...Remdesivir, Lopinavir + Ritonavir, Tenofovir, ...
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Treatment outcomes and plasma level of ritonavir-boosted lopinavir monotherapy among HIV-infected patients who had NRTI and NNRTI failure
... with lopinavir/ritonavir is mild to moderate diarrhea ...discontinue ritonavir-boosted lopinavir due to gastro-intestinal adverse ...event. Lopinavir/ritonavir soft gel capsules ...
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Sex differences in responses to antiretroviral treatment in South African HIV-infected children on ritonavir-boosted lopinavir- and nevirapine-based treatment
... visit. Lopinavir, ritonavir, and nevirapine plasma concentrations were determined using validated LC-MS/MS assays devel- oped in the Division of Clinical Pharmacology, Cape Town, South ...for ...
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