low-temperature Si/sub 3/N/sub 4/ membrane technology
Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... nitrocellulose membrane (Bio-Rad Laboratories, Hercules, CA, USA) blocked with 5% dry milk and exposed to rabbit polyclonal antibody anti- KCNQ1 (H-130: sc-20816, [Santa Cruz Biotechnology, Santa Cruz, CA USA]; ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... Samples of tumor tissue weighing 0.1 g was collected from each mouse and homogenized for detection of P- glycoprotein, Bcl-2, Bax, and caspase-3. Briefly, the tissues were extracted with Triton X-100, and the ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... Ferric chloride hexahydrate (FeCl 3 ⋅ 6H 2 O), ferrous chloride tetrahydrate (FeCl 2 ⋅ 4H 2 O), and ammonium hydroxide (25 wt%) were purchased from Fluka (Buchs, Switzerland). D, L-lactide and glycolide were ...
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The effects of magnetite (Fe<sub>3</sub>O<sub>4</sub>) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH<sub>3</sub>) cells and in RAW 264.7 macrophages
... by membrane hyperpolarization would be ...Fe 3 O 4 NPs on I MEP with a half-maximal inhibitory concentration (IC 50 ) value of 46 µ M could derive from the direct binding of the nanoparticles to the ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... molecular weights. Immunoblots for expression of p38, p-p38, JNK, p-JNK, HO-1, ERK, c-Jun, cleaved caspase 3, Bcl2, Bax, P50, p53, Nrf2, Akt, and GAPDH were detected. All antibodies for Western blot in this study ...
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Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... functional positions provided by PLGA for loading DOX onto DMP. Enhanced drug loading is due to the increased number of functional “arms” on the DMP surface. More functional arms could provide more functional positions ...
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Preparation of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles coated with gallic acid for drug delivery
... different pH levels which are similar to the pH of the stomach and the pH of the blood. Generally, the pH of the stomach varies from 1–2 to 4–5. After eating, the stomach releases proteases and hydrochloric acid ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... Fe 3 O 4 magnetic nanoparticles (Fe 3 O 4 ...Fe 3 O 4 -MNPs were synthesized, and their characteristics such as particle size, zeta potential, and X-ray diffraction patterns were ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... aged 4 weeks and weighing 20–22 g were divided into six groups, with 10 mice per group (half male and half ...intermittent low temperature sterilization of the Fe 3 O 4 , sterile normal ...
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Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... and the blots were stained with specific primary antibodies, including anti-bcl-2, anti-bax, anti-survivin, anti-bcl-rambo, anti-active caspase-3, and anti-GAPDH antibodies overnight at 4 ° C. Then, the ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... culture dishes; cells were either untreated (control), or treated with DTX (1 nM) or MgNPs-Fe 3 O 4 (10 µ g/mL or 100 µ g/mL) in the absence or presence of DTX (1 nM). Aspirated medium was collected to ...
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The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... The levels of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-10 (IL-10), and interferon- γ (INF- γ ) in serum were measured in duplicate using enzyme-linked immunosorbent assay kit according to the ...
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Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... The functional groups on the particles were identified by Fourier transform infrared (FT-IR) spectroscopy using a JASCO IR-4200 (JASCO Inc, Easton, MD, USA). The per- centage of Dex and alendronate that were coated onto ...
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Daunorubicin-loaded magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> overcome multidrug resistance and induce apoptosis of K562-n/VCR cells <em>in vivo</em>
... Fe 3 O 4 (MNPs-Fe 3 O 4 ) on K562-n/VCR cells in ...MNPs-Fe 3 O 4 , and group D received DNR-loaded MNPs-Fe 3 O 4 ...MNPs-Fe 3 O 4 can overcome ...
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NH<sub>4</sub>HCO<sub>3</sub> gas-generating liposomal nanoparticle for photoacoustic imaging in breast cancer
... NH 4 HCO 3 solutions with regard to time ...NH 4 HCO 3 solution quickly reached a peak value and decreased soon ...NH 4 HCO 3 ...NH 4 HCO 3 decomposes into CO 2 , ...
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Temperature-dependent and time-dependent effects of hyperthermia mediated by dextran-coated La<sub>0.7</sub>Sr<sub>0.3</sub>MnO<sub>3</sub>: in vitro studies
... placed in Petri plates. After 48 hours, the cells were exposed to RF-induced Dex-LSMO-mediated hyperthermia (43 ° C, 45 ° C, or 47 ° C) . At 0 hours and after 24 hours of treatment, the cells were fixed with ...
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Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... Fe 3 O 4 /Au nanoparticles were synthesized by assembling gold nanoparticles on SH-modified Fe 3 O 4 and using them as nanocarriers for immobilization of HRP and a secondary antibody (Ab 2 ...
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Vancomycin-modified Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@Ag microflowers as effective antimicrobial agents
... Fe 3 O 4 @ SiO 2 @Ag ...Van/Fe 3 O 4 @SiO 2 @Ag microflowers (Figure 3B and ...Fe 3 O 4 @SiO 2 @Ag microflowers are surrounded by a thin membrane-like layer with ∼ ...This ...
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Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... cell membrane and distributed in the cell ...MNPs-Fe 3 O 4 induced apoptosis not only through influencing the regulatory factors in the intrinsic mitochondrial pathway such as bax and bcl-2, but also ...
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In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... O 3 . Using TEM characterization, Fe m O n -SiO 2 composite flake-like and SiO 2 -Fe m O n core-shell IONPs demonstrated spherical shape with mean diameter of 98 ± 22 and 101 ± 19 nm, respectively ...
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