LTP—Long-Term Potentiation
Endogenous acetylcholine modulates synaptic plasticity in the hippocampus in vivo
... 2000) LTP in area C A l were dem onstrated to converge on and activate p42 M APK (also referred to as extracellular signal-regulated kinase 2, ERK2 ) (Roberson et ...the long-lasting, protein ...
123
Stress and long term potentiation
... Long term potentiation (LTP) is a widely investigated phenomenon seen in several regions o f the central nervous system ...1993). LTP can be recognised electropysiologically by ...
166
No requirement of TRPV1 in long-term potentiation or long-term depression in the anterior cingulate cortex
... the LTP and LTD data, the initial slope of fEPSPs was measured by taking the rising phase between 10% and 90% of the peak response, normalized and presented sep- arately in both superficial and deep layers as a ...
13
On the role of arachidonic acid in long-term potentiation
... following LTP, such as bifurcation o f dendritic spines so that where before there was one, stimulation can cause a second to emerge (Geinisman et ...of LTP (termed iate-LTP’) is believed to be the ...
179
Investigation Of The Molecular Mechanisms Of Synaptic Tagging And Capture
... Hippocampal long-term potentiation (LTP) has been studied as the primary model for memory storage because of its long duration, input specificity and associativity (Bliss & Gardner- ...
152
Differential sensitivity of three forms of hippocampal synaptic potentiation to depotentiation
... aptic potentiation is not a unitary process, but it can be di- vided into several temporally and mechanistically distinct ...short-term potentiation (STP), and a persistent phase known as ...
5
Cholinergic modulation of hippocampal long-term potentiation in chronic cerebral hypoperfused rats
... or long-term potentiation (LTP) is one of the most important neurochemical foundations in learning and memory, deficits of which occur as a result of ...in LTP impairment of CCH rat ...
16
Expression mechanisms underlying different forms of hippocampal long-term potentiation
... of LTP can be induced in situations where the cell type, animal age and other experimental conditions are kept constant (reviewed by Raymond, ...of LTP decay functions, with time constants of 2 hours, 4 ...
189
Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer’s disease model mice
... Molecular signaling mechanisms underlying Alzheimer’s disease (AD) remain unclear. Maintenance of memory and synaptic plasticity depend on de novo protein synthesis, dysregulation of which is implicated in AD. Recent ...
15
A study of long-term potentiation in transgenic mice over-expressing mutant forms of both amyloid precursor protein and presenilin-1
... Another possibility for our finding, a lack of effect on LTP in the DbTg mice, is that other factors may be required for generating AD-related impairments in hip- pocampal function, for example altered tau [52]. ...
9
Erythropoietin enhances hippocampal long-term potentiation and memory
... The long-lasting effect of EPO on neuroplasticity was con- firmed by analyses of paired-pulse facilitation, STP, LTP and STD, as well as of spontaneous synaptic activity in acute hippocampal slices, ...
16
Long term potentiation decay and memory loss are mediated by AMPAR endocytosis
... decaying LTP that lasted for less than 1 hour in AD mice (aged ...in LTP maintenance in these ...of LTP, converting this decaying LTP into nondecaying LTP (GluA2 3Y : ...
15
Seasonal variation of long term potentiation at a central synapse in the medicinal leech
... either potentiation or depression) or non-plastic (<20% change) and the percentage of plastic synapses was calculated over each ...in LTP over the year ...exhibited LTP also exhibited a high ...
6
Neural plasticity of mushroom body extrinsic neurons in the honeybee brain
... and long-term ...stimulation, LTP was induced in the PE1 neuron of some ...(associative LTP) was not seen in PE1 recordings of most preparations, suggesting that unknown modulatory conditions ...
16
Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats
... pain. Long-term potentiation (LTP) of insular excitatory synaptic transmission is believed to mediate pathological pain [12, ...insular LTP requires both N-methyl-D-aspartate receptor ...
20
An investigation of the processes underlying late-phase long-term potentiation
... following LTP induction (Isaac et a l, 1995; Liao et a l , 1995; Durand et a l, ...ing LTP induction, electrophysiologically tagged AM PARs move into synapses via a process dependent on the interaction of ...
310
ApoE isoform-dependent changes in hippocampal synaptic function
... isoform, long-term potentiation (LTP) is significantly enhanced in apoE4 TR mice versus apoE2 TR ...in LTP induction require NMDA-receptor function, and apoE isoform expression alters ...
18
Down-regulation of miR-9* in the peripheral leukocytes of Huntington’s disease patients
... A single miR-9 precursor produces two mature miRNAs, miR-9 and miR-9*, which are abundantly expressed in both developing and adult brain [34]. MiR-9 is highly conserved across vertebrate species and shows brain-specific ...
5
Imaging synaptic plasticity
... investigate long-term changes in synaptic efficacy following the electrical, pharmacological, or genetic manipulation of synaptic ...of long-term potentiation (LTP), as reported ...
10
Protective Effects of Enriched Environment Against Transient Cerebral Ischemia-Induced Impairment of Passive Avoidance Memory and Long-Term Potentiation in Rats
... Furthermore, involvement in the complex environment after ischemic injuries improves neural plasticity, includ- ing greater neurogenesis, reactive synaptogenesis and dendritic restructuring (Matsumori et al., 2006). How- ...
10