Lung carcinomas
Human papillomavirus-16 presence and physical status in lung carcinomas from Asia
... of lung cancer is smok- ...on lung cancer ...in lung ACs among non-smoking ...increased lung cancer risk in relation to mosquito coil use [20], which is commonly used in Asian countries, ...
7
Low Levels of p27 in Association With Deregulated p53-pRb Protein Status Enhance Tumor Proliferation and Chromosomal Instability in Non-Small Cell Lung Carcinomas
... Overexpression of p27 Kip1 appears to be more cytotoxic to cancer cells compared to that of p21 (44,45), with apoptosis being the putative mecha- nism underlying such cytotoxicity. However, we found no association ...
12
EGFR-TKI-sensitive mutations in lung carcinomas: are they related to clinical features and CT findings?
... with lung carcinomas and who underwent EGFR testing at the First Affiliated Hospital of Wenzhou Medical University (Wenzhou, Zhejiang, People’s Republic of China) between January 1, 2011, and November 31, ...
9
fur gene expression as a discriminating marker for small cell and nonsmall cell lung carcinomas
... muscle, lung, and testis. mRNA levels in specimens of human lung tissue without neoplastic lesions were also very ...human lung carcinomas of different histopathological types revealed a ...
6
Genetic and Molecular Coordinates of Neuroendocrine Lung Tumors, with Emphasis on Small-cell Lung Carcinomas
... Topoisomerase II (Topo II) participates in DNA replication, transcription, and recombination (261). There are two subtypes of this enzyme: Topo II (170 kDa) and Topo II (180 kDa). Their expression is not correlated and ...
18
Relationship of the K-ras/c-mos Expression Patterns With Angiogenesis in Non-Small Cell Lung Carcinomas
... c-mos Cytoplasmic and membranous immunoreac- tivity was considered to be evidence of c-mos ex- pression. As we have previously described, nuclear staining in the presence of cytoplasmic and/or mem- branous reactivity was ...
8
Incidence and patterns of ALK FISH abnormalities seen in a large unselected series of lung carcinomas
... to lung cancer in 2012 ...classifies lung cancer into non- small cell lung cancer (NSCLC, 85%) and small-cell lung cancer ...all lung cancer cases in the United States, ...in ...
6
Genetic alteration profiling of patients with resected squamous cell lung carcinomas
... Loss of PTEN expression has been reported to occur in 20% to 93% of SqCLC [29–33]. In the present study, we found that 42.7% of SqCLC demonstrated loss of PTEN protein expression, which was consist with previously ...
12
Original Article Downregulation of ALDH1A1 expression in non-small cell lung carcinomas – its clinicopathologic and biological significance
... through the DNA hypermethylation could be a possible mechanism of ALDH1A1 downregula- tion in NSCLCs. However, our experiment using inhibitors for DNA methyltransferase (5-Aza-dc) and histone deacetylase (trichostatin A) ...
12
CD10/NEP in non small cell lung carcinomas Relationship to cellular proliferation
... The cell surface metalloproteinase CD10/neutral endopeptidase 24.11 (NEP) hydrolyzes a variety of peptide substrates and reduces cellular responses to specific peptide hormones. Because CD10/NEP modulates ...
9
Genome-wide DNA methylation profiling of non-small cell lung carcinomas
... paired lung tissue sample (y axis). (C) Raw reads from a lung sample (above panel) and its matching tumor sample (middle panel) in the position chr2:176,716,200 to 176,738,910 viewed in the UCSC genome ...
18
Production of a Low Molecular Weight Eosinophil Polymorphonuclear Leukocyte Chemotactic Factor by Anaplastic Squamous Cell Carcinomas of Human Lung
... A peptide of approximately 300-400 daltons exhibiting in vitro chemotactic activity for human polymorphonuclear (PMN) leukocytes, with a preference for the eosinophil series, was isolated from extracts of anaplastic ...
12
Original Article KDM4A, KDM4B and KDM4C in non-small cell lung cancer
... dependent carcinomas compared to lung carcinomas which may explain the different KDMA’s asso- ciation with tumor size as compared with lung ...in lung carcinoma thus also con- tributing ...
7
Epigenetic regulation of mucin genes in human cancers
... Many studies of epigenetic gene regulation have addressed tumor suppressor genes (Garinis et al. 2002). Meanwhile, evidence for promoter hypomethylation of oncogenes has gradually emerged in tumors of several organs ...
12
A strategy for pulmonary resection after contralateral diaphragm plication: a surgical case report
... right lung carcinomas complicated by left diaphragmatic ...double lung carcinomas. Five years later, two new lung tumors in her right lower lobe and left diaphragmatic eventration were ...
5
CD10/neutral endopeptidase 24 11 regulates fetal lung growth and maturation in utero by potentiating endogenous bombesin like peptides
... Abstract Bombesin-like peptides BLPs are mitogens for bronchial epithelial cells and small cell lung carcinomas, and increase fetal lung growth and maturation in utero and in organ cultu[r] ...
6
Immunotherapy of Cancer—A Historical Note
... We also studied human breast and lung carcinomas. First we established if these tumors had infiltrating lym- phocytes, like in our methycholanthrene induced guinea pig sarcoma. The results were positive. So ...
5
Case Report Parotid gland and cerebellum metastasis of lung cancer: a case report
... cell carcinomas accounts for ap- proximately 30% of all non-small cell carcinoma of the lungs ...[8]. Lung carcinomas are characterized by their insidious onset, difficulty in detection, early ...
7
Original Article Expression of HDAC9 in lung cancer – potential role in lung carcinogenesis
... some lung tumors are sensitive to conventional chemotherapeu- tic agents or certain molecular targeting agents, many are not [3, ...of lung carcinogene- sis is important for developing a novel thera- peutic ...
8
Cancer frequency: Kars province
... mortality rates considering the geographical characteristics and living conditions.2 Despite the increase in cancer registry comprehensibility in our country, there are still shortcomings in the reports even though the ...
7