Lymphatic Endothelial Cells
Migration of lymphatic endothelial cells and lymphatic vascular development in the craniofacial region of embryonic mice
... ABSTRACT Lymphatic development in mice is initiated in the trunk at embryonic day (E) ...craniofacial lymphatic endothelial cells (LECs) and the developmental process of lymphatic ...
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Lymphatic endothelial cells promote productive and latent HIV infection in resting CD4+ T cells
... the lymphatic vessels in the lymph nodes are microvascular ...cer cells [35], respond more strongly to certain growth factors [36], and respond to IL-1 and lipopolysaccharides with higher sensitivity ...
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Pulmonary and pleural lymphatic endothelial cells from pediatric, but not adult, patients with Gorham-Stout disease and generalized lymphatic anomaly, show a high proliferation rate
... the lymphatic endothelial cells (LECs) of these LMs do not dived rapidly after birth, although their clinical course is progressive in nature ...
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Andes Virus Infection of Lymphatic Endothelial Cells Causes Giant Cell and Enhanced Permeability Responses That Are Rapamycin and Vascular Endothelial Growth Factor C Sensitive
... Human lymphatic endothelial cells from HPS patients contain hantavirus antigens (86), suggesting that in vitro LEC responses observed here may also contribute to HPS in ...human endothelial ...
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Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells
... Myelocytic cells (such as macrophages and dendritic cells) are the primary hosts for Mtb after infection [17] and virtually all in vitro studies of PDIM biology have used murine or human macrophages as a ...
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Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk
... The endothelial cells of the vertebrate lymphatic system assemble into complex networks, but local cues that guide the migration of this distinct set of cells are currently ...for ...
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Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation
... CD11c+CD11b+ cells to migrate from inflamed skin to the skin-draining LNs (schematic shown in Figure ...FITC+CD11c+CD11b+ cells that had migrated from the inflamed dermis (Figure 2I and ...a ...
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Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL
... stromal cells, expressed ITGAV, suggesting that they could anchor to matrix proteins through ITGAV/ITGB3 (Fig ...stem cells or mast cells [24,32], ITGA2b is required to translocate ITGB3 to the cell ...
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Diphtheria toxin–mediated ablation of lymphatic endothelial cells results in progressive lymphedema
... capillary lymphatic regeneration rather than restoration of the collecting lymphatic ...of lymphatic injury ...of lymphatic stasis is a major regulator of chronic inflammation and ...a ...
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Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF induced arthritis in mice
... of lymphatic vessel contraction via its vasodilatory signal in LSMCs [20, ...collecting lymphatic vessels ...of lymphatic drainage in cir- rhotic rats ...in lymphatic vessels efferent from ...
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H , N and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice
... To determine whether the Hras-induced VEGFR3 increase has a functional effect on LECs, we performed a network formation assay in the presence of MAZ51, a selective kinase inhibitor of VEGFR3 Fig. 4. Characterization of ...
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Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis
... Next, cells were dehydrated at room temperature using a graded ethanol series (70%, 80%, 90%, 95%, 100%) and then detached from plastic with propylene oxide and washed several times, followed by gradual ...
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Biological functions of macrophage-derived Wnt5a, and its roles in human diseases
... dermal lymphatic capillaries ...in lymphatic endothelial cells (LECs), suggesting that LEC-derived Wnt5a may promote lymphangiogenesis in an autocrinal manner, just like EC- derived Wnt5a in ...
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Everolimus for Primary Intestinal Lymphangiectasia With Protein-Losing Enteropathy
... submucosal lymphatic channels along the villi (Fig 1B). Staining for the lymphatic marker D2-40 was positive in the luminal cells (Fig ...the lymphatic endothelial cells (Fig ...
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Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation
... dermal cells using real-time ...that lymphatic endothelial cells express the majority of Angpt2 and Tie1 in wild-type dermis, whereas Angpt1 and Vegfc were expressed at substantially higher ...
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Systemic sclerosis sera affect fibrillin 1 deposition by dermal blood microvascular endothelial cells: therapeutic implications of cyclophosphamide
... In lymphatic vessels, fibrillin microfibrils form filaments anchoring lymphatic endothelial cells (ECs) to the surrounding elas- tic fibers ...the lymphatic vessels, contributing to the ...
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TGFβ signaling is required for sprouting lymphangiogenesis during lymphatic network development in the skin
... Dermal lymphatic endothelial cells (LECs) emerge from the dorsolateral region of the cardinal veins within the anterior trunk to form an intricate, branched network of lymphatic vessels during ...
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Direct and efficient cellular transformation of primary rat mesenchymal precursor cells by KSHV
... MM cells expressed vascular endothelial markers β-catenin, ICAM-1, vWF, and VEGFR-1; lymphatic endothelial markers VEGFR-3 and LYVE-1; and hematopoietic precursor markers CD34 and ...vascular ...
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MicroRNA miR-466 inhibits Lymphangiogenesis by targeting prospero-related homeobox 1 in the alkali burn corneal injury model
... primary lymphatic endothelial cells (HDLEC), miR-466 mimic transfection suppressed Prox1 mRNA and protein expression, while miR-4305 mimic transfection did ...transfected cells, and this ...
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Hypoxia Induces Permeability and Giant Cell Responses of Andes Virus-Infected Pulmonary Endothelial Cells by Activating the mTOR-S6K Signaling Pathway
... and lymphatic endothelial cells (MECs and LECs, respectively) and nonlytically enhances the permeability of interendothelial cell adherence junctions in response to vascular endothelial growth ...
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