macrophage C-type lectin
The macrophage C type lectin receptor CLEC5A (MDL 1) expression is associated with early plaque progression and promotes macrophage survival
... of macrophage MDL-1 expression also accompanied with alterations of lesional macrophage content, we conducted the TUNEL assay and found that overexpression of MDL-1 contrib- uted to significant decrease of ...
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Different Potential of C-Type Lectin-Mediated Entry between Marburg Virus Strains
... cellular C-type lectins for virus attachment to ...express C-type lectins, C-type lectin-mediated entry is thought to be a possible determinant of virus tropism and ...of ...
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Composition, Structure, Dynamics and Function of C-Type Lectin Receptor Domains
... PBS (diluted from PBS, 10×, Cellgro, Manassas, VA). The goat polyclonal IgG AF2534, which is specific for human CD206 (also known as MMR, Macrophage Mannose Receptor), was obtained commercially (R&D Systems, ...
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Tumor therapy in mice via antigen targeting to a novel, DC restricted C type lectin
... the macrophage mannose receptor or the Fcγ receptors, as well as others more restricted to DCs, such as DEC-205, DC-SIGN, langerin, asialoglycoprotein receptor, or blood DC antigen 2 (BDCA-2) (reviewed in ...the ...
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The Macrophage Galactose-Type Lectin Can Function as an Attachment and Entry Receptor for Influenza Virus
... of type A influenza viruses, or (ii) MAb C1/1, which detects the HA of BJx109, followed by FITC-conjugated goat anti-mouse Ig (Millipore, ...block C-type lectin receptors prior to addition of ...
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Phylogenetic Analysis of C Type Lectin from Toxocara canis Infective Larvae and Comparison with the C Type Lectin Fam-ily in the Immune System of Mouse and Human
... of C type lectin and collagen ...consists C type lec- tins which act as receptor-mediated endocyto- sis, and include the asialoglycoprotein receptor (ASGPR), the macrophage ...
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Mouse Macrophage Galactose-type Lectin (mMGL) is Critical for Host Resistance against Trypanosoma cruzi Infection
... Reverse transcriptase-PCR. Total RNA was ex- tracted from Mφ obtained as described above from untreated or in vitro T. cruzi infected (21 days after infection) WT or mMGL-/- mice, using the TRIzol reagent (Sigma). cDNA ...
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C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map
... receptor C; CD, cluster of differentiation; NPC, nasopharyngeal carcinoma; DC-SIGN, dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin; TNF, tumor necrosis factor; IL, interleukin; IP, ...
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Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation
... MGL1-deficient mice are highly susceptible to EAE We next investigated the relevance of MGL in an in vivo model of autoimmune neuroinflammation. Given the non-redundant functions of the murine MGL1 and MGL2 homologs and ...
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Targeting CLL-1 for acute myeloid leukemia therapy
... identify C-type lectin-like molecule-1 (CLL-1) which is expressed on 92% AML and absent on granulocyte-macrophage progenitors (GMPs) ...
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Macrophage Receptors for Influenza A Virus: Role of the Macrophage Galactose-Type Lectin and Mannose Receptor in Viral Entry
... the lectin domains of MGL or ...and C-type lectin interactions, may enhance the efficiency of this route of ...the lectin domains of MMR is es- sential for efficient entry of the virus ...
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The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus
... a further 6 to 8 h before they were fixed and stained for viral NP. (A) Representative images from confocal microscopy show RFP-labeled Rab5 and Rab5 S34N expression in all cell lines (red, left panels) and newly ...
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Hemagglutinating activity of Chickpea extracts for lectin
... The lectin activity greatly varies between the seeds that were investigated, although they belong to closely related ...different lectin composition in these seed ...higher lectin activity compared ...
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Characterization of Caenorhabditis elegans lectin-binding mutants.
... (Because surface lectin binding is restricted to small regions of the adult wild-type animal, mutants missing this lectin binding are difficult to identify in a dissecting micro- sc[r] ...
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Cloning and characterization of a mannose binding C type lectin gene from salivary gland of Aedes albopictus
... a C-type lectin ( AaegmosGCTL-1 ) induced by West Nile Virus (WNV) infection, can interact with WNV in a calcium- dependent manner, and facilitate flavivirus invasion in vivo and in vitro ...
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CD300f immunoreceptor contributes to peripheral nerve regeneration by the modulation of macrophage inflammatory phenotype
... into macrophage activation related to macrophage polarization and their pro-inflammatory or anti-inflammatory responses have been reported [17, 18], and recently macrophages have been classified as M1 or ...
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The human C-type lectin 18 is a potential biomarker in patients with chronic hepatitis B virus infection
... hepatitis C virus, hepatitis D virus, or human immunodeficiency virus; decompensated liver disease; other forms of liver disease; hepatocellular carcinoma at baseline; coexisting severe medical diseases or cancer; ...
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The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120
... virus type 1 (HIV-1) is typically characterized by relatively low levels of neutralizing antibodies, particularly those with broad activity against many different isolates of the virus (6, 23, 35, 36, ...
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The Structure of the Poxvirus A33 Protein Reveals a Dimer of Unique C-Type Lectin-Like Domains
... The current vaccine against smallpox is an infectious form of vaccinia virus that has significant side effects. Alternative vaccine approaches using recombinant viral proteins are being developed. A target of subunit ...
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Characterization of a human hematopoietic progenitor cell capable of forming blast cell containing colonies in vitro
... A hematopoietic cell (CFU-B1) capable of producing blast cell containing colonies in vitro was detected using a semisolid culture system. The CFU-B1 has the capacity for self- renewal and commitment to a number of ...
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