Male germ cell-specific
Characterization of eight novel proteins with male germ cell-specific expression in mouse
... spermatogenic cell-specific genes have been shown to play critical roles in spermatogenesis and fertili- zation, it is possible that the present novel proteins are involved in these reproductive ...their ...
12
Endocrine disruptors, gene deregulation and male germ cell tumors
... and germ cell differentiation with different mechanisms and diverse molecular pathways, as shown by their patterns of gene expression ...define specific gene expression signatures after unsupervised ...
16
The first bromodomain of Brdt, a testis specific member of the BET sub family of double bromodomain containing proteins, is essential for male germ cell differentiation
... homozygous-mutant male mice are reduced in number and are misshapen Histological sections of the epididymides were prepared from mice of all three genotypes and at different ...
9
Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background
... C57BL/6J germ cells might underlie their ability to arrest or activate cell death pathway(s) prior to ...strain- specific contributions to the cell cycle and reprogramming are ...the ...
10
SirT1 is required in the male germ cell for differentiation and fecundity in mice
... of germ cell ...antibodies specific for histone H4 acetyl lysine residues demonstrated that acetylation of H4K5, K8 and K12 was decreased, whereas acetylation of residue K16 remained unchanged in ...
10
Germ cells and germ cell transplantation
... In mice, premeiotic oogonia will enter meiotic prophase and give rise to growing oocytes in fragments of embryonic ovary main- tained in an organ culture system (McLaren and Buehr, 1990); this transition does not require ...
6
HP1γ function is required for male germ cell survival and spermatogenesis
... for 30 minutes to reduce background staining. All anti- bodies were diluted in Tris-buffered saline with 10% bovine serum albumin (BSA). Endogenous peroxidase was inactivated with 3% H 2 O 2 , and diaminobenzidine (DAB; ...
9
A cystatin related gene, testatin/cresp, shows male specific expression in germ and somatic cells from the initial stage of murine gonadal sex differentiation
... the germ cells that also expressed the germ cell-specific Oct3/4 ...16 germ cells gave a detectable signal representing testatin/cresp mRNA expres- sion, while 6 out of 16 somatic cells ...
8
Expression of a large number of novel testis specific genes during spermatogenesis coincides with the functional reorganization of the male germ cell
... Int J Dev BioI 39 719 726 (1995) 719 Expression of a large number of novel testis specific genes during spermatogenesis coincides with the functional reorganization of the male germ cell CHRISTER HOOG[.] ...
8
Delayed male germ cell sex specification permits transition into embryonal carcinoma cells with features of primed pluripotency
... embryonic germ cells harbor features of naïve pluripotency prior to sex-specific differentiation, they lack one characteristic of this cell type, ...inner cell mass of blastocysts (Le Bin et ...
12
Evaluation of specific germ cell genes expression in mouse embryonic stem cell-derived germ cell like cells treated with bone morphogenetic protein 4 in vitro
... in male gonads is produced, which terminates cell cycle at G1, and prevents the cells from entering meiosis ...stem cell factor (SCF) (7), tumor necrosis factor (TNF) (8) and retinoic acid (RA) (9) ...
12
Identification of target genes for spermatogenic cell-specific KRAB transcription factor ZFP819 in a male germ cell line
... in germ cell line (GC‑2 cell) We previously reported that the KRAB domain of Zfp819 has repressive activity using the GAL4-UAS sys- tem in somatic cell lines (HEK 293T and NIH3T3) ...the ...
15
The control of sexual identity in the Drosophila germline
... that germ cells face along the way (see Box 1 for a discussion of ...a germ cell acquires a male versus female identity, but also how sexual identity influences other events, such as the ...
9
Differential Response of Mouse Male Germ-Cell Stages to Radiation-Induced Specific-Locus and Dominant Mutations
... In an attempt to provide a systematic assessment of the frequency and nature of mutations induced in successive stages of spermato- and spermiogenesis, X-irradiated male mice were re-mat[r] ...
12
The polyubiquitin gene Ubi p63E is essential for male meiotic cell cycle progression and germ cell differentiation in Drosophila
... are male and female infertile (Ryu et ...mutant male germ cells arrest in meiotic prophase, resembling the magn arrest ...The specific events that demand high levels of free ubiquitin ...
10
DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages
... female germ cells, as XXY male germ cells also possess this reactivation capability (Mroz et ...migratory germ cells carry parent-of-origin-specific imprinting marks and high levels of ...
8
Stimulation of ovarian stem cells by follicle stimulating hormone and basic fibroblast growth factor during cortical tissue culture
... Background: Cryopreserved ovarian cortical tissue acts as a source of primordial follicles (PF) which can either be auto-transplanted or cultured in vitro to obtain mature oocytes. This offers a good opportunity to ...
10
Spermiogenesis and Male Fertility Require the Function of Suppressor of Hairy-Wing in Somatic Cyst Cells of Drosophila
... female germ cells begin differentiation in late larval develop- ment (Gilboa and Lehmann 2004; Song et ...2007), male germ cells begin these processes at the end of embryogenesis (Le Bras and Van ...
16
Csk differentially regulates Src64 during distinct morphological events in Drosophila germ cells
... or cell-cell contacts was observed in Src64 LOF germaria ...the germ cells and raise questions about potential roles for germline signals during stalk ...follicle cell-germ cell ...
12
A novel eIF4G homolog, Off schedule, couples translational control to meiosis and differentiation in Drosophila spermatocytes
... There are striking parallels to the role of eIF4G2 during spermatogenesis in other organisms. For instance, there are also two major isoforms of eIF4G in Caenorhabditis elegans, encoded by ifg- 1. When the longest ...
11