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Malignant Giant Cell Tumor

Secondary malignant giant cell tumor of bone due to malignant transformation 40 years after surgery without radiation therapy, presenting as fever of unknown origin: a case report

Secondary malignant giant cell tumor of bone due to malignant transformation 40 years after surgery without radiation therapy, presenting as fever of unknown origin: a case report

... a giant cell tumor of bone of his left distal femur and underwent bone curettage and avascular fibula grafting at that ...secondary malignant giant cell tumor of bone. The ...

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Primary de novo malignant giant cell tumor of kidney: a case report

Primary de novo malignant giant cell tumor of kidney: a case report

... osteoclast-like giant cells have been reported in various extraosseous epithelial sites [3- ...rare tumor and majority of the cases reported seem to occur in association with papillary, tran- sitional, ...

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Heat Shock Protein 70 Expression in Giant Cell Tumor of Bone and Its Clinical Application

Heat Shock Protein 70 Expression in Giant Cell Tumor of Bone and Its Clinical Application

... especially malignant tumors such as leukemia and osteosarcoma [3] ...of tumor cell apopto- sis ...these malignant tumors seemed to correlate with the aggressiveness of the tumors [9] ...in ...

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A case of giant cell tumor of the breast, clinically suspected as malignant breast tumor

A case of giant cell tumor of the breast, clinically suspected as malignant breast tumor

... The tumor was composed mainly of oval and spindle mono- nuclear histiocyte-like cells and multinucleated giant cells ...the tumor, which did not fill the criteria of ductal carcinoma in situ ...

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A giant pelvic epidermoid cyst with malignant transformation to squamous cell carcinoma

A giant pelvic epidermoid cyst with malignant transformation to squamous cell carcinoma

... develop malignant change ...cystic tumor was less than 30% and that various imaging modalities were not useful in establishing a definitive diagnosis ...with malignant transformation is difficult as ...

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A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastases

A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastases

... Giant cell tumors of bone are neoplasms of stromal cells that recruit a mononuclear population of hematopoietic origin ...multinucleated giant cells may in turn produce factors that support growth of ...

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Multifocal Metachronous Giant Cell Tumor: Case Report and Review of the Literature

Multifocal Metachronous Giant Cell Tumor: Case Report and Review of the Literature

... scattered giant cells, hemosiderin, and occasional inflammatory cells ...multicentric giant cell tumors includes brown tumor, Paget’s disease, osteomyelitis, fibrous dysplasia, giant ...

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Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?

Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?

... Giant cell tumor, excluding its prototype in bone, is usually a benign but local aggressive neoplasm originating from tendon sheath or soft ...tissue. Malignant behavior is ...rare. ...

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Conventional Giant Cell Tumor of the Rib with Pulmonary Metastases: A Case Report and Review of Literature

Conventional Giant Cell Tumor of the Rib with Pulmonary Metastases: A Case Report and Review of Literature

... "giant cell rich osteosarcoma" which was ruled out due to the absence of cellular ...the tumor had reactive bone formation rather than neoplastic osteoid formation which is a significant ...

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Case Report Primary pleomorphic liposarcoma of liver: a case report and review of the literature

Case Report Primary pleomorphic liposarcoma of liver: a case report and review of the literature

... or malignant, when it shows huge space-occupying ...nucleated giant cells and pleomorphic spindle cell under microscopy by H&E staining [1, 3, 6, ...

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Clinicopathological Correlation of Primary Malignant Bone Tumors—An Observational Study

Clinicopathological Correlation of Primary Malignant Bone Tumors—An Observational Study

... Primary malignant tumors arising from bone are uncommon but important malig- nant neoplasms which account for ...primary malignant bone tumors is available from this region of West Bengal in the ...primary ...

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Primary cancers of the small bowel: About 20 cases

Primary cancers of the small bowel: About 20 cases

... of malignant tumors of the small bowel, col- lected in the department of general surgery of Habib Thameur Hospital in Tunis (Tunisia), from January 1994 through June ...carcinoid tumor (8 cases), ...

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Recurrent primary mediastinal giant cell tumor of soft tissue with radiological findings: a rare case report and literature review

Recurrent primary mediastinal giant cell tumor of soft tissue with radiological findings: a rare case report and literature review

... osteoclast-like giant cells and mononuclear cells with a background of high-vascularity ...the tumor and follow-up. The previous four cases presented no tumor recurrence during the follow-up, whereas ...

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Giant cell tumor of bone and tenosynovial tissue : surgical outcome

Giant cell tumor of bone and tenosynovial tissue : surgical outcome

... during cell-cycle progression ...secondary malignant GCTB and may thus play a role in malignant progression ...in tumor formation, implicating other causes of genomic instability ...

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Imaging of primary tumors of sacrum

Imaging of primary tumors of sacrum

... or malignant. In malignant tumors soft tissue component is more ...the tumor is benign or ...osteochondroma, giant cell tumor and aneurysmal bone cyst. Malignant tumors ...

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Giant-cell tumor of bone: treatment options and role of denosumab

Giant-cell tumor of bone: treatment options and role of denosumab

... Giant-cell tumor of bone (GCTB) is a rare tumor typically affecting the bones of skeletally mature young adults, with peak incidence in the third and fourth decades of ...multinucleated ...

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Vertebral Giant Cell Tumor: Diagnosis Difficulties and Therapeutics’ Challenges

Vertebral Giant Cell Tumor: Diagnosis Difficulties and Therapeutics’ Challenges

... no malignant transformation of the GCT. Because of the tumor size, the surrounding soft tissues involvement and the non radical tumor excision, our patient presents a high risk of recurrence, and a ...

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Small Cell Ovarian Cancer in Adolescents: Report of Two Cases and Review of the Literature

Small Cell Ovarian Cancer in Adolescents: Report of Two Cases and Review of the Literature

... small cell tumors are highly aggressive ...this tumor is unilateral salpingo-oophorectomy in stage IA, that has a reported postoperative disease-free survival rate of approximately 33% throughout 1 to 13 ...

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Cervical spine giant cell bone tumor: a case report

Cervical spine giant cell bone tumor: a case report

... GCTs are rare tumors and are quite rare in the cervical spine. Various treatment options such as surgery, radio- therapy, embolization, cryotherapy, and chemical adju- vants are used for spinal GCTs. Denosumab has been ...

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A Clinicopathological Study of Ovarian Tumors and
The Role of Immunohistochemical Proliferative
Marker Ki 67.

A Clinicopathological Study of Ovarian Tumors and The Role of Immunohistochemical Proliferative Marker Ki 67.

... of cell cycle (G1S,G2M) and is absent in resting phase ...positive tumor cells (Ki 67 labelling index) is often correlated with clinical course of ...

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