MANNICH BASE
Newly Synthesized Oxadiazole Based Mannich Base Derivatives of Fatty Acid: In Silico Study and in Vivo Anti-Hyperglycaemic Estimation
... Therefore, consider ing that fatty acid derivatives possess a polar chain and an oxadiazole moiety at end which are required for good anti- hyperglycaemic activity, novel mannich base derivatives having ...
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A New Mannich Base and its Metal Complexes along with their Antimicrobial and Antifungal screening
... The Mannich reaction is an organic reaction which consists of an amino alkylation of an acidic proton placed next to a carbonyl functional group with formaldehyde and ammonia or any primary or secondary ...The ...
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Corrosion and Inhibition of P110 steel in 20% HCl Solution by Mannich Base Inhibitor
... of Mannich base molecular on P110 steel ...of Mannich base inhibitor may be attributed to a compact and coherent film formed on P110 steel and reduced chemical attacks of H + and Cl - ...
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Synthesis and physico chemical characterisation of new mannich base and its metal complexes
... A solution of 5 mmol of metal salts and the Mannich base (10 mmol, 2.92 g) in 40 ml ethanol and chloroform mixture (1:6, ν / ν ) was boiled under reflux at 58 o C (b.p. of azeotropic mixture) for 3 h. The ...
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Synthesis, Characterization and Antimicrobial Study of New Nalidixic Acid Mannich Base Derivatives
... acid mannich base derivatives by adopting appropriate synthetic steps with expected broader spectrum of ...synthesized mannich derivatives including intermediates by physical and spectral data like ...
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Synthesis and Structural Characterization of Some Cobalt (II) Complexes with a Mannich Base Derived From Morpholine and Maleic Hydrazide
... new Mannich base N-(1-morpholinomethylmaleichydrazide) ,(MMMH) was synthesized through Mannich reaction and its Cobalt(II) chloro, bromo and nitrato complexes have been ...
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Synthesis and evaluation of hybrid mannich base-tetraoxane derivatives as potent anti-malarial agents
... [15]. Mannich base phenol side chain within the tetraoxane template has shown to deliver a new class of hybrid drug with potency for a dual mechanism of action versus ...the Mannich base ...
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Study on the Synthesis, Characterization and Antimicrobial studies of the Transition Metal Complexes of the Novel Mannich Base Derived from Pyridazine Derivative
... amino -NH disappears implying its condensation after deprotonation. These results confirms the formation of the Mannich base. In all the complexes, band due to νC=O and νC-N shifted towards lower frequency ...
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AN INNOVATIVE SYNTHESIS OF NEW MANNICH BASE, ITS METAL COMPLEXES AND THEIR ANTIBACTERIAL STUDIES
... We reported synthesis of new mannich base and its transition metal complexes in green manner. The structure of synthesized compounds confirmed with help of UV, IR, 1 HNMR, 13 CNMR spectroscopic techniques ...
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The Inhibition Effect of a Novel Mannich Base on the Corrosion of A3 Mild Steel in 1.0 M Hydrochloric Acid Solution
... The Mannich base DFAPA synthesized in this study could be adsorbed on the MS surface and thus behave as an excellent corrosion inhibitor of A3 MS in ...
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SYNTHESIS, CHARACTERIZATION OF MANNICH BASE TRANSITION METAL COMPLEXES: DNA BINDING AND ANTI BACTERIAL STUDIES
... the Mannich base ligand succinimide, methoxy benzaldehyde and thiourea ...new Mannich base derived from SMBTUand the metal complexes with Mn (II), ...
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SYNTHESIS, CHARACTERIZATION AND EVALUATION OF ANTIOXIDANT AND ANTHELMINTIC ACTIVITY OF SUBSTITUTED MANNICH BASE ARYL IMIDAZOLE DERIVATIVES
... The structures of the synthesized derivatives of substituted Mannich base Aryl Imidazole were established by IR, NMR, Mass spectra. The purity of synthesized compounds had been checked on TLC plates using ...
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Synthesis and biological evaluation of 1, 3-dihydroxyxanthone mannich base derivatives as anticholinesterase agents
... the Mannich base compound inhibited both cholinesterases in mixed-type manners, suggesting they might simul- taneously interact with the AS and PAS of both en- ...of Mannich base derivatives ...
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Identification of Mannich Base as a Novel Inhibitor of Mycobacterium Tuberculosis Isocitrate by High-Throughput Screening
... (Beijing) Co.,Ltd; DNA purification kit was purchased from SBS Genetech Co., Ltd; BamHI, HindIII, T4 DNA ligase, and dNTP were purchased from Takara; Ni-Sepharose and ȀKTA prime were from Amersham Biosciences. Isocitrate ...
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Crystal structure of the di Mannich base 4,4′ dichloro 3,3′,5,5′ tetramethyl 2,2′ [imidazolidine 1,3 diylbis(methylene)]diphenol
... 2004). Mannich bases are also convenient models for studying the nature of hydrogen bonding and other weak non-covalent interactions, as they contain at least one phenolic or naphtholic hydroxy group as a proton ...
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Cholinesterase Inhibition Activity and Docking Simulation Study of Coumarin Mannich Base Derivatives
... Inhibition of acetylcholinesterase and butyrylcholinesterase (AChE and BuChE) as two major forms of cholinesterases (ChEs) is considered as the common approach for the treatment of Alzheimer's disease (AD). The present ...
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SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF SOME d10 METAL COMPLEXES WITH A NEW MANNICH BASE N-[(DIPHENYLAMINO) METHYL] ACETAMIDE
... work, Mannich base derived from the condensation of benzaldehyde, diphenylamine and acetamide, and its metal complexes with Zn(II), Cd(II) and Hg(II), are synthesized and are characterized using different ...
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SYNTHESIS, CHARACTERIZATION, AND DNA BINDING INTERACTION STUDIES OF A NEW MANNICH BASE AND IT’S METAL COMPLEXES
... In the continuation of our research work, herein, we report the synthesis of a new Mannich base derived from succinimide, methoxy benzaldehyde and thiourea (LIGAND) and the metal complexes with Ni(II) and ...
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Synthesis, characterization, biological evaluation and docking studies of pyrimidine imidazole mannich base derivatives as transaminase bioainhibitors
... In conclusion, a series of novel pyrimidine imidazole mannich base derivatives were synthesized. The anti-bacterial and anti-fungal activities havebeen carried out. Among tested compounds, the derivatives ...
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Metal-based Antimicrobial Agents: Synthesis, Characterization and Biological Studies of Mannich Base Derivatives of Benzimidazole and Their Metal Complexes
... Novel Mannich base derivatives of Benzimidazole were prepared through the condensation reaction of benzimidazole derivative with formaldehyde and primary and/ secondary ...of Mannich bases have also ...
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