Mannose binding
Human mannose binding protein activates the alternative complement pathway and enhances serum bactericidal activity on a mannose rich isolate of Salmonella
... human mannose-binding protein (MBP) is a multimeric serum protein that is divided into three domains, a cysteine-rich NH2-terminal domain that stabilizes the collagen alpha helix of the second domain and a ...
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Association of mannose binding lectin 2 genotype and serum levels with prognosis of sepsis
... Severe sepsis and septic shock cause 30% to 50% of all deaths in intensive care units (ICUs) [1]. Numerous studies have suggested that individuals vary in their ability to resist infection [2-4]. Genetic variations, such ...
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Mannose binding lectin: a biomarker of systemic lupus erythematosus disease activity
... 29. Glesse N, Monticielo OA, Mattevi VS, Brenol JC, Xavier RM, da Silva GK, Dos Santos BP, Rucatti GG, Chies JA: Association of mannose-binding lectin 2 gene polymorphic variants with susceptibility and ...
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Complement Mediated Neutralization of Dengue Virus Requires Mannose Binding Lectin
... ABSTRACT Mannose-binding lectin (MBL) is a key soluble pathogen recognition protein of the innate immune system that binds specific mannose-containing glycans on the surfaces of microbial agents and ...
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Association of mannose binding lectin gene polymorphisms with the development of pulmonary tuberculosis in China
... [2]. Mannose-binding lectin (MBL) is an acute-phase serum protein in the collection family that recognizes a pathogen by its carbohydrate recog- nition ...
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Mannose Binding Lectin as a Diagnostic Marker for Coronary Artery Disease in Hypertensive Patients
... “MANNOSE BINDING LECTIN AS A DIAGNOSTIC MARKER FOR CORONARY ARTERY DISEASE IN HYPERTENSIVE PATIENTS” is the bonafide work done by me at Institute of Biochemistry, Madras Medical College under the expert ...
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Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease
... of mannose-binding lectin deficiency ranged from ...had mannose-binding lectin concentrations below the normal range and we found no association between mannose-binding lectin ...
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Mannose binding lectin does not explain the course and outcome of pregnancy in rheumatoid arthritis
... MBL: mannose- binding lectin; mon, months; OR: odds ratio; PARA Study: Pregnancy-induced Amelioration of Rheumatoid Arthritis Study; PCR: polymerase chain reaction; PP: postpartum; RA: rheumatoid arthritis; ...
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Original Article Identification of mannose-binding lectin as a mechanism in progressive immunoglobulin A nephropathy
... The paraffin section was dewaxed and cultured in sodium citrate buffer solution (0.01 mol/l, pH = 6.0) at 95°C for 15 min. After cooled to room temperature (25°C), the section was digested using 0.5% pancreatin and the ...
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Original Article Serum mannose-binding lectin levels in patients with ischemic stroke
... Abstract: Background: The purpose of this study was to investigate the serum levels of mannose-binding lectin (MBL) in the Chinese patients with acute ischemic stroke (AIS). Method: We conducted a ...
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A Single Asparagine-Linked Glycosylation Site of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Facilitates Inhibition by Mannose-Binding Lectin through Multiple Mechanisms
... no inhibition of viral infection was detected with VSV, Ebola virus, and HCV pseudoviruses (Fig. 2A and B). The results were highly reproducible, and the inhibition of the SARS-S pseudovirus infection by pdMBL could be ...
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Mannose binding lectin deficiency with eosinophilic meningoencephalitis due to Angiostrongylus cantonensis in children: a case series
... and mannose-binding lectin by time-resolved fluorometry. Mannose-binding lectin deficiency was observed in the three ...in mannose-binding lectin level with increased IgG, C4 and ...
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Interference with the Mannose Binding and Epithelial Cell Adherence of Escherichia coli by Sublethal Concentrations of Streptomycin
... streptomycin, mannose binding activity and epithelial cell adherence of the ...in mannose binding activity was dose related over a range of concentrations between ...
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Prominently Increased of Mannose Binding Lectin (MBL) and Myeloperoxidase (MPO) Levels in Severe Valve Regurgitation and Heart Failure of Rheumatic Heart Disease
... Rheumatic heart disease (RHD) is mediated by an abnormal immunological response following a Streptococcus pyogenes infection that induces a disturbance of oxidants and antioxidants balances. Mannose-binding ...
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Mannose Binding Lectin Genotypes Influence Recovery from Hepatitis B Virus Infection
... Mannose binding lectin (MBL) is a central component of the innate immune response and thus may be important for determining hepatitis B virus (HBV) ...
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Deficiency of functional mannose binding lectin is not associated with infections in patients with systemic lupus erythematosus
... for mannose-binding lectin (MBL) variant alleles were at an increased risk of acquiring serious infections in comparison with patients who were heterozygous or homozygous for the normal ...
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Elevated levels of vitamin D and deficiency of mannose binding lectin in dengue hemorrhagic fever
... One of the major pathways of complement activation is initiated by binding of the virus to mannose binding lectin (MBL). MBL is a pattern recognition molecule that recognizes specific sugar molecules ...
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Strong predictive value of mannose binding lectin levels for cardiovascular risk of hemodialysis patients
... ADPKD: autosomal dominant polycystic kidney disease; BMI: body mass index; BSA: bovine serum albumin; C5b‑9: membrane attack complex; C‑event: cardiac event; CABG: coronary artery bypass grafting; CI: confidence ...
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The pandemic (H1N1) 2009 influenza virus is resistant to mannose binding lectin
... defense. Consequently, the susceptibility of a pathogen to an innate immune response inevitably determines its pathogenesis. Human seasonal influenza A viruses are susceptible to mannan-binding protein, also known ...
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Significance of mannose-binding lectin deficiency and nucleotide-binding oligomerization domain 2 polymorphisms in Staphylococcus aureus bloodstream infections: a case-control study
... Organ dysfunction was less pronounced in patients with NOD2 mutations indicated by significantly lower SOFA scores (median 2.5 (IQR 0-3.75) vs. 4.5 (IQR 2-6), p=0.02) and the fact that the majority (8/16 (50%)) ...
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