Mapping the Cdc28 binding site in Yih1
Fast Binding Site Mapping using GPUs and CUDA † *
... total binding energy between the protein and the ligand, and that they bind a wide variety of small molecule probes ...called binding site ...likely binding site on a protein surface ...
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Mapping of the complement C1q binding site on Trichinella spiralis paramyosin
... through binding to C8/9 [5, 18] and C1q [4] as a survival strategy in the ...host. Binding of TsPmy to human C1q inhibited C1q-initiated classical complement activation and C1q-induced macrophages migration ...
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A Genetic Approach to Mapping the p53 Binding Site in the MDM2 Protein
... (A) Five different plasmids were translated and [35S] -labeled in vitro: luciferase as a negative control, full length and 1-115 of human wild-type Mdm2 as positive controls, and the two[r] ...
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Mapping of Vps21 and HOPS Binding Sites in Vps8 and Effect of Binding Site Mutants on Endocytic Trafficking
... Vps21 binding only had a modest effect on Ste6 trafficking and CPY sorting, while dele- tions that abolish interaction with the class C/HOPS core com- plex caused severe trafficking ...
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Mapping an antibody-binding site and a T-cell-stimulating site on the 1A protein of respiratory syncytial virus.
... were immunized once with 1A(45-60), and the draining lymph node cells were tested for ability to proliferate in response to in vitro restimulation with the nested set of peptides describ[r] ...
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Mapping the Orthosteric Binding Site of the Human 5-HT3 Receptor Using Photo-crosslinking Antagonists
... Just Accepted “Just Accepted” manuscripts have been peer-reviewed and accepted for publication. They are posted online prior to technical editing, formatting for publication and author proofing. The American Chemical ...
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Mapping of the CXCR4 Binding Site within Variable Region 3 of the Feline Immunodeficiency Virus Surface Glycoprotein
... interaction. Binding studies demon- strated that MAbs specific for the V3 region of SU were more efficient than L2- or V4-specific MAbs in blocking the SU binding to ...SU binding to CXCR4. By this ...
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Dynamics of transcription factor binding site evolution
... mismatch binding model results in redundancy of genotype classes, with a binomial distribution (red) of genotypes in each mismatch class (some examples of degenerate sequences shown) D) The mapping from the ...
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Fine Mapping of the Interaction of Neutralizing and Nonneutralizing Monoclonal Antibodies with the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120
... b12 binding to monomeric gp120 and neutralization ...b12 binding. Whereas b12 binding was maintained or increased, binding by five nonneutralizing anti-CD4bs MAbs (b3, b6, F105, 15e, and F91) ...
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The tethered agonist approach to mapping ion channel proteins: toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor
... In our preliminary report only Tyr-O3Q at position α149 was studied. We now find that tether length significantly influences the effectiveness of the agonist at this position. As shown in Figure 2.5, Tyr-O3Q represents ...
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Mapping of the VP40-Binding Regions of the Nucleoprotein of Ebola Virus
... 3). These results indicated that NP interacts with VP40 intra- cellularly and that the NP-VP40 complex is present at the budding site. The NP-VP40 interaction is essential for nucleocapsid in- corporation into ...
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Mapping small molecule binding data to structural domains
... our mapping against manually curated binding site annotations from Uniprot and also against annotation extracted from crystallographic struc- tures in ...our mapping for multi-domain proteins. ...
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Mapping the 3D structures of small molecule binding sites
... structural binding site ...between binding sites derived from different ...between binding sites of the serine proteases prothrombin and cationic trypsin that is consistent with literature ...
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Protein Binding Site Similarities as Driver for Drug Repositioning
... Scoring binding site alignments bears problems in terms of which matches in an alignment are ...the mapping of amino acid side chain properties to backbone carbon ...matching binding ...
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Functional microRNA binding site variants.
... miRNA binding sites can lead to a range of effects on miRNA::mRNA interac- tions, from complete disruption of binding to the cre- ation of a new miRNA binding ...
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Ahr Transcription Factor Binding Site
... AHR binding at that putative AHRE, indicating that align was hardly a functional AHRE in ...TF binding profiles stored as position frequency matrices PFMs and TF ...the binding sites for ...
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Transcription Factor Binding Site Analysis
... Several of these differentially methylated sites were validated by bisulfite pyrosequencing. For the Decision Tree classifiers predicting transcription factor target genes, Shyr C, Pearson Correlation and Spearman ...
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Stem cell factor binding to retrovirus primer binding site silencers.
... A binding were investigated, and partial purification steps indicated the factor to be a heparin-Sepharose-binding moiety of greater than 100 ...in binding studies, suggesting that they may be ...
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Mapping Site Using An Excel Spreadsheet
... & mapping tool Datawrapper to ceiling ...Excel site counts can get an excel mapping ...spreadsheet mapping and imported data field use these examples of the office? The export visible when ...
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CiteSeerX — Binding Site on the Light Neurofilament Subunit
... tubulin-binding site located on the light neurofilament subunit, selectively enters in glioblastoma cells where it disrupts their microtubule network and inhibits their ...
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