Matrix metalloproteinase (MMP)-2
The effect of tomato juice on the expression of matrix metalloproteinase-2 (MMP-2) and type-1 collagen on the vaginal wall of the menopausal rats
... of MMP- 2 and type-1 collagen on the vaginal wall of the menopausal ...of MMP- 2 and type-1 collagen was examined using immunohistochemistry ...
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Active synovial matrix metalloproteinase 2 is associated with radiographic erosions in patients with early synovitis
... matrix metalloproteinase (MMP) family are thought to play a central role in the degradation of the extracellular matrix of articular bone and ...gelatinases MMP-2 [9,10] and ...
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Original Article Serum levels of matrix metalloproteinase-2 and matrix metalloproteinase-9 have clinical significance for the evaluation of the prognosis of patients with ruptured intracranial aneurysms after interventional therapy
... of matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) before and after interventional therapy of ruptured intracranial aneurysm (IA), as well ...
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Integrin Alpha V Beta 3 Matrix Metalloproteinase 2 (MMP 2), Cross Talk
... metastasis. MMP activity is tightly regulated at several levels, from transcription, to proenzyme activation and finally by inhibition with ...TIMPs. MMP-2 is secreted in association with ...
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Matrix metalloproteinase-2, tissue inhibitor of matrix metalloproteinase-2, and transforming growth factor beta 1 in the aqueous humor and serum of patients with pseudoexfoliation syndrome
... the control groups. This finding suggests that these molecules may not be major risk factors for the investigated disease, but they might be the outcomes. According to recent reports, increased oxidative stress and a ...
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Roles of low-density lipoprotein receptor-related protein 1 in tumors
... regulating matrix metalloproteinase (MMP)-2 and MMP-9 expression and functions but also inhibits cell apoptosis by regulating the insulin receptor, the serine/ threonine protein kinase ...
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Immunohistochemical expression of Matrix Metalloproteinase-2 (MMP-2) in inguinal hernia
... MMPs play a key role in development of various vascular diseases. They are predominantly associated with atherosclerosis. MMPs cause intimal thickening in the walls of large arteries, as a repair response to vessel wall ...
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High threshold of β1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2)
... MT1- MMP expression. The interaction between β1 integrin and MT1-MMP blocks MT1-MMP internalization and causes increased MMP-2 ...stimulate MMP-2 acti- vation, and induce ...
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Circulating matrix metalloproteinase MMP-9 and MMP-2/TIMP-2 complex are associated with spontaneous early pregnancy failure
... and MMP-2/TIMP-2, code Ge- 213 for ...and MMP-2/ TIMP-2 complex were incubated for 60 minutes, or over- night in the case of ...for MMP-2/TIMP-2 complex, ...
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Expression and importance of matrix metalloproteinase 2 and 9 (MMP-2 and -9) in human trophoblast invasion
... tured in M-199 medium (Beit-Ha'Emek, Israel) contain- ing 10% Fetal Calf Serum (FCS, Beit-Ha'Emek, Israel) and penicillin/streptomycin (Beit-Ha'Emek, Israel). Cell cul- ture was maintained in a humidified atmosphere ...
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Fluid-induced, shear stress-regulated extracellular matrix and matrix metalloproteinase genes expression on human annulus fibrosus cells
... the MMP-1 and -3 genes was upregulated in rabbit tendon cells following 1 dyne/cm 2 fluid-induced shear stress for 6 h in a specially designed multi-slide flow device ...
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The matrix metalloproteinase and insulin-like growth factor system in oral cancer – a prospective clinical study
... of MMP-2, MMP-3, MMP-13, IGF-1, and IGFBP-3 and tumor recurrence, metastasis, or prognosis, the serum concentrations were divided into two ...
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Effect of Aliskiren on renal using UUO mmp 3/timp 2 model
... of metalloproteinase-2 (TIMP-2) pointed out that, the renal rats with unilateral ureteral obstruction (UUO) model occur after interstitial fibrosis and renal tissue damage or may show Matrix ...
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The Interaction of Stroke Risk Factors, Clinical Outcomes and Matrix Metalloproteinase 9 Levels with the Reduction of Vascular Endothelial Growth Factor A Levels at the Incidence of Brain Edema in Acute Ischemic Stroke Patients
... and MMP-9 levels in blood, history of hypertension, history of diabetes mellitus, history of hypercholesterolemia, history of heart disease, blood pressure at the admission time, fasting blood glucose level, ...
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Toll like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis
... Cell migration is essential for tissue infiltration during the inflammatory process and is initiated by cell polar- isation and the formation of membrane protrusions at the leading edge [12]. Integrin-linked activation ...
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<p>MMP-2, MMP-9, TIMP-1, and TIMP-2 in the Peripheral Blood of Patients with Differentiated Thyroid Carcinoma</p>
... extracellular matrix breakdown in breast ...nases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumor- ...al. Matrix metalloproteinase (MMPs) expression by ...
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Adiponectin is a potential catabolic mediator in osteoarthritis cartilage
... of metalloproteinase (TIMP)-2 and downregulates IL-1b-induced matrix metalloproteinase (MMP)-13 in OA chondrocytes, whereas Lago et ...IL-6, MMP-3, MMP-9, and MCP-1 in ...
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Albumin induces upregulation of matrix metalloproteinase-9 in astrocytes via MAPK and reactive oxygen species-dependent pathways
... in MMP-9 was specific to the type of albumin (globulin- and fatty acid-free BSA) and the species used in these experi- ...of MMP-9 after 24 hours by zymo- ...in MMP-9 compared with control cells ...
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Synergistic and protective effect of atorvastatin and amygdalin against histopathological and biochemical alterations in Sprague-Dawley rats with experimental endometriosis
... Langendonckt et al. 2002; Giudice and Kao 2004). Ele- vated levels of matrix metalloproteinase-2 (MMP2) and MMP-9 have also been reported (Chung et al. 2001; Osteen et al. 2003). The treatment ...
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Clinical evaluation of a matrix metalloproteinase 12 cleaved fragment of titin as a cardiovascular serological biomarker
... The following competitive ELISA protocol was opti- mised for use with the MMP-12 titin monoclonal anti- body. The selected monoclonal antibodies were labelled with horseradish peroxidase (HRP) using the Lightning- ...
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