mature B cells
IgD attenuates the IgM-induced anergy response in transitional and mature B cells
... anergic B cell mRNA response to ...anergic mature B cells to test for any evidence that surface IgD and IgM differ in their capacity to elicit responses to ...anergic B cells: ...
11
Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68.
... of cells, an assay system that distinguishes productive from latent infection, demonstrates that MuMT spleens are latently but not productively ...lack mature B cells, g HV-68 is able to ...
6
Mature B cells class switched to IgD are autoreactive in healthy individuals
... autoreactive B cells is critical to understanding and treating autoim- mune ...from B cells that have class switched to IgD via genetic recombination (and thus become class switched to Cδ ...
9
Burkitt’s Lymphoma Is a Malignancy of Mature B Cells Expressing Somatically Mutated V Region Genes
... Materials and Methods: Rearranged VK region genes from 10 K-expressing sporadic and endemic BL-derived cell lines (9 IgM and 1 IgG positive) and three K-express- ing endemic BL biopsy sp[r] ...
11
The presence of CLL-associated stereotypic B cell receptors in the normal BCR repertoire from healthy individuals increases with age
... on B cell subsets in peripheral blood of 155 immunologically healthy individuals in four age categories (range 20-95y) via multi-parameter flow ...antigen-experienced B cell receptor (BCR) repertoire of ...
12
Checkpoints that control B cell development
... developing B cell repertoires at check- points 2 and ...apoptotic cells complexed with serum IgM, C1q, and C4b, thereby preventing the accumula- tion of nuclear antigen and the subsequent activation of ...
9
B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8⁻ dendritic cells require the intramembrane endopeptidase SPPL2A
... accumulate mature B cells normally (Benlagha et ...in B cell maturation remains ...on B cells, revealing a critical role for regulated intramembrane prote- olysis in B ...
10
Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl 2 levels
... cultured mature B cells in the presence of nitric oxide or nitric oxide- donor substances delays programmed cell death as determined by the appearance of DNA laddering in agarose gel electrophoresis ...
8
CD19: a biomarker for B cell development, lymphoma diagnosis and therapy
... CD19 is a biomarker for B cells. CD19 functions as the dominant signaling component of a multimolecular complex on the surface of mature B cells, alongside complement receptor CD21, and ...
7
The IgH 3’ regulatory region influences lymphomagenesis in Igλ-Myc mice
... and B-cell fate. In plasma cells, transcribed IgH and IgL loci often colocalized in transcription factories and an IgL transcription defect might translate into lowered IgH ...less mature lymphomas ...
10
The role of Rac GTPases in B cell development and activation
... The B cell developmental abnormalities noted in the Æac-deficient mice analysed required more mechanistic inquiry to uncover why deficiency in Rac2 and also Racl had profound affects on the generation and/or ...
241
B cell antigen receptor isotypes : implications for immune memory
... splenic B cell phenotype existed between the three principal lines (GG4, MG2 and MM4) used in this ...on mature B cells, as well as varying degrees of receptor editing away from the transgene ...
248
MicroRNAs in B cell development and malignancy
... in mature B cells ...in B cells after engagement of the antigen receptor and expo- sure to inflammatory mediators ...a B cell-intrinsic ...
10
Regenerative change of Bone Marrow Hematopoietic Stem Cell (BMHSCs) on Secondary Leukemia and Lung Injury Induced as Adverse Chemotherapeutic (etoposide) Drug in Albino Rats
... effector cells in allergic inflammation, in addition to mast cells and basophils [54], but recently discovered the antitumor activity for their where, eosinophils express both FcεRs, should be able to ...
33
In vitro differentiation of isolated stem cells from the midgut of Manduca sexta larvae
... Prior to dissection, animals were surface-sterilized by consecutive immersion for approximately 2 min each in baths of 20 % detergent (Septisol, Vestal Laboratories, St Louis, MO), 0.1 % p-hydroxybenzoic acid methyl ...
7
Cortisol increases Na(+)/K(+) ATPase density in plasma membranes of gill chloride cells in the freshwater tilapia Oreochromis mossambicus
... chloride cells in the filamental and lamellar epithelia were quantified using a video image data-analysing system (VIDAS; Kontron, Germany) as described recently (Dang et ...of cells per mm length of ...
7
In Vivo Tropism of Attenuated and Pathogenic Measles Virus Expressing Green Fluorescent Protein in Macaques
... CD11c-positive cells were identified as the major target ...in B and T lymphocytes in lymphoid tissues and viral dissemination to the skin and the submucosa of respiratory ...
11
RGMB and neogenin control cell differentiation in the developing olfactory epithelium
... progenitor cells also give rise directly to SUS cells, which form a monolayer in the apical region of the OE, indicating that signaling mechanisms must be in place to control cell fate choice in these ...
13
A modular transcriptome map of mature B cell lymphomas
... We generated an over-expression-spot map which sum- marizes all red over-expression spots observed in the single-sample portraits (Fig. 2a, see [23]). In total, 13 spot modules A–M were identified, where each of them ...
20
Existence-uniqueness and Monotone approximation for an erythropoiesis age-structured model
... Abstract: We develop a monotone approximation to the solution of an age- structured model which describes the regulation of erythropoiesis, the process by which red blood cells are developed. The convergence of ...
15