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mechanistic models

Fitting mechanistic models to Daphnia panel data within a panelPOMP framework

Fitting mechanistic models to Daphnia panel data within a panelPOMP framework

... apply mechanistic models on ecological panel data within panelPOMP framework and use panel iterated filtering (PIF) as maximization algorithm (Bretó et ...apply mechanistic models on panel ...

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Forecasting and uncertainty quantification using a hybrid of mechanistic and non-mechanistic models for an age-structured population

Forecasting and uncertainty quantification using a hybrid of mechanistic and non-mechanistic models for an age-structured population

... a mechanistic model; we refer to these approaches as“non-mechanistic ...autoregressive models, ...a mechanistic model based on biological knowledge, they do not include parameters that ...

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Comparison of mechanistic models in the initial rate enzymatic hydrolysis of AFEX-treated wheat straw

Comparison of mechanistic models in the initial rate enzymatic hydrolysis of AFEX-treated wheat straw

... Different mechanistic models have been used in the literature to describe the enzymatic hydrolysis of pretreated ...different models have been applied to different substrates, most of these ...

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Mechanistic models enable the rational use of in vitro drug-target binding kinetics for better drug effects in patients.

Mechanistic models enable the rational use of in vitro drug-target binding kinetics for better drug effects in patients.

... drug concentration decreases with 10% every minute (if you solve the equation by taking time steps of 1 minute). For compartmental models, differential equations are used to describe the concentration in each ...

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Integrating the influence of weather into mechanistic models of butterfly movement

Integrating the influence of weather into mechanistic models of butterfly movement

... While the long-term ecological consequences are com- plex to predict, we have demonstrated that the current relationship between behaviour and weather can be de- fined and included in mechanistic movement ...

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Performance Prediction of the NCAT Test Track Pavements Using Mechanistic Models.

Performance Prediction of the NCAT Test Track Pavements Using Mechanistic Models.

... Predicted permanent deformations for NCAT test sections using ESALs with as-built layer thicknesses for base layers.. Measured versus predicted wireline rut depths for NCAT test section[r] ...

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Prediction of storm transfers and annual loads with data based mechanistic models using high frequency data

Prediction of storm transfers and annual loads with data based mechanistic models using high frequency data

... process-based models, with fewer parameters, have also been developed for phosphorus transfer and have been applied with reasonable success to specific catchments ...the models would only be applicable to ...

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Mechanistic-enriched models: integrating transcription factor networks and metabolic deregulation in cancer

Mechanistic-enriched models: integrating transcription factor networks and metabolic deregulation in cancer

... In line with these thoughs (following several other scholars such as Brigandt and Bech- tel, for instance) we wonder how integration is taking place in the emerging frame of Systems Biology. No doubt there is a debate on ...

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MASS TRANSFER MODELING OF HEPATIC DRUG ELIMINATION USING LOCAL VOLUME AVERAGING APPROACH

MASS TRANSFER MODELING OF HEPATIC DRUG ELIMINATION USING LOCAL VOLUME AVERAGING APPROACH

... several mechanistic models have been presented for predicting the hepatic drug elimination, an improved model can be achieved if the liver structural properties ...known models followed by performing ...

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A mechanistic model of infection: why duration and intensity of contacts should be included in models of disease spread

A mechanistic model of infection: why duration and intensity of contacts should be included in models of disease spread

... simulation models on quantities, such as intensity and duration of an exposure to infectious material, is possible and ...Existing mechanistic transmission models applied in simulations of disease ...

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On Mechanistic Modeling of Gene Content Evolution: Birth-Death Models and Mechanisms of Gene Birth and Gene Retention

On Mechanistic Modeling of Gene Content Evolution: Birth-Death Models and Mechanisms of Gene Birth and Gene Retention

... robust mechanistic inference that is ...and mechanistic modeling requires interdisciplinary knowledge in statistics and various areas of biology that must fit together, where there is a need for statistical ...

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A unifying framework for quantifying the nature of animal interactions

A unifying framework for quantifying the nature of animal interactions

... predictive, mechanistic models showing how utilisation distributions arise from the underlying movement and interaction ...equation models [30], from which the resulting spatial distributions can be ...

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Efficient Bayesian model choice for partially observed processes : with application to an experimental transmission study of an infectious disease

Efficient Bayesian model choice for partially observed processes : with application to an experimental transmission study of an infectious disease

... peting mechanistic models of transmission, up to an ABC tolerance of = 1 around each data ...the models with extremely poor support were removed (according to the Occam’s Window criteria), there ...

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Priorities and opportunities in the application of the ecosystem services concept in risk assessment for chemicals in the environment

Priorities and opportunities in the application of the ecosystem services concept in risk assessment for chemicals in the environment

... The fi rst step in the problem formulation for an ES-based ERA is to identify the contaminant(s) of concern, the landscapes potentially ex- posed and the ES of concern (Maltby et al., 2017a). The ES of concern are those ...

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Legitimising data driven models: exemplification of a new data driven mechanistic modelling framework

Legitimising data driven models: exemplification of a new data driven mechanistic modelling framework

... These models have become one of the most popular ap- plication areas for data-driven modelling in hydrology over recent years (Abrahart et ...superior models with an even higher degree of ...

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EXPERIMENTAL MODELS FOR ALZHEIMER’S DISEASE: A MECHANISTIC VIEW

EXPERIMENTAL MODELS FOR ALZHEIMER’S DISEASE: A MECHANISTIC VIEW

...  Intracerebroventricular Administration of Colchicine: Colchicine, an alkaloid extracted from some plants of the lily family, has been used for centuries to treat acute gouty arthritis. Since 1973, it has been ...

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Hydrodynamic Integrated Modelling of Basic Water Quality and Nutrient Transport in Swarna River Basin, Udupi, Karnataka

Hydrodynamic Integrated Modelling of Basic Water Quality and Nutrient Transport in Swarna River Basin, Udupi, Karnataka

... numerically with the help of a certain mathematical equation which governs the movement of the pollutant or the flow of the system (Mechanistic model) or can be developed based on a collection of data (Statistical ...

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Mechanistic and ecological explanations in agent based models of cognition

Mechanistic and ecological explanations in agent based models of cognition

... the mechanistic (“sub-froggy”) ...the mechanistic how-question in terms of some sort of neural circuitry diagram, we have described what McDowell calls an enabling condition for the agent-level ...this ...

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Key Metabolites and Mechanistic Changes for Salt Tolerance in an Experimentally Evolved Sulfate Reducing Bacterium, Desulfovibrio vulgaris

Key Metabolites and Mechanistic Changes for Salt Tolerance in an Experimentally Evolved Sulfate Reducing Bacterium, Desulfovibrio vulgaris

... ABSTRACT Rapid genetic and phenotypic adaptation of the sulfate-reducing bacte- rium Desulfovibrio vulgaris Hildenborough to salt stress was observed during experi- mental evolution. In order to identify key metabolites ...

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Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injury

Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injury

... cardiac models compared with hepatic models may reflect the relative specificity of some forms of drug-induced cardiotoxicity, in contrast with the rather pleiotropic and diverse manifestations of ...

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