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Memory B cell

A High Frequency of HIV Specific Circulating Follicular Helper T Cells Is Associated with Preserved Memory B Cell Responses in HIV Controllers

A High Frequency of HIV Specific Circulating Follicular Helper T Cells Is Associated with Preserved Memory B Cell Responses in HIV Controllers

... of B cell ...potent memory B cell responses without high NAb titers (40, 55, 56) and that assessing the “silent” memory B cell compartment is needed to evaluate the ...

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HIV-exposed uninfected infants show robust memory B cell responses in spite of a delayed accumulation of memory B cells: An observational study in the first two years of life.

HIV-exposed uninfected infants show robust memory B cell responses in spite of a delayed accumulation of memory B cells: An observational study in the first two years of life.

... HIV-exposed uninfected infants show robust memory B cell responses in spite of a 1.. delayed accumulation of memory B cells: An observational study in the first two 2.[r] ...

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Evidence of Early B-Cell Dysregulation in Simian Immunodeficiency Virus Infection: Rapid Depletion of Naïve and Memory B-Cell Subsets with Delayed Reconstitution of the Naïve B-Cell Population

Evidence of Early B-Cell Dysregulation in Simian Immunodeficiency Virus Infection: Rapid Depletion of Naïve and Memory B-Cell Subsets with Delayed Reconstitution of the Naïve B-Cell Population

... of B-cell deficiencies during the chronic stage of ...HIV-induced B-cell deficit have been proposed, a clear mecha- nistic understanding of this loss of B-cell functionality is ...

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HIV-Exposed Uninfected Infants Show Robust Memory B-Cell Responses in Spite of a Delayed Accumulation of Memory B Cells: an Observational Study in the First 2 Years of Life

HIV-Exposed Uninfected Infants Show Robust Memory B-Cell Responses in Spite of a Delayed Accumulation of Memory B Cells: an Observational Study in the First 2 Years of Life

... of memory B cells (CD19 ⫹ CD10 ⫺ CD27 ⫹ ) (a), unswitched memory B cells (CD19 ⫹ CD10 ⫺ CD27 ⫹ IgM ⫹ ) (b), and switched memory B cells (CD19 ⫹ CD10 ⫺ CD27 ⫹ IgM ⫺ ) (c) ...

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HIV-exposed uninfected infants show robust memory B cell responses in spite of a delayed accumulation of memory B cells: An observational study in the first two years of life.

HIV-exposed uninfected infants show robust memory B cell responses in spite of a delayed accumulation of memory B cells: An observational study in the first two years of life.

... of memory B cells (CD19 ⫹ CD10 ⫺ CD27 ⫹ ) (a), unswitched memory B cells (CD19 ⫹ CD10 ⫺ CD27 ⫹ IgM ⫹ ) (b), and switched memory B cells (CD19 ⫹ CD10 ⫺ CD27 ⫹ IgM ⫺ ) (c) ...

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Pertussis-Specific Memory B-Cell and Humoral IgG Responses in Adolescents after a Fifth Consecutive Dose of Acellular Pertussis Vaccine

Pertussis-Specific Memory B-Cell and Humoral IgG Responses in Adolescents after a Fifth Consecutive Dose of Acellular Pertussis Vaccine

... two B-cell responses most likely represent two forms of indepen- dently controlled immunological ...and memory B-cell responses (38–40), as well as by mouse studies showing that serum ...

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Impaired Naive and Memory B-Cell Responsiveness to TLR9 Stimulation in Human Immunodeficiency Virus Infection

Impaired Naive and Memory B-Cell Responsiveness to TLR9 Stimulation in Human Immunodeficiency Virus Infection

... activate B lymphocytes directly, potentially influencing their function and ...assess B-cell responsiveness to TLR9 agonists in human immunodeficiency virus (HIV) disease, we examined the ability of ...

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Epstein-Barr Virus Can Establish Infection in the Absence of a Classical Memory B-Cell Population

Epstein-Barr Virus Can Establish Infection in the Absence of a Classical Memory B-Cell Population

... the memory B-cell population (characterized by markers: CD27 ⫹ , IgM ⫺ , IgD ⫺ ) as the spe- cific site of viral persistence in peripheral blood (4); however, there is still debate over whether these ...

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Absence of IgD CD27(+) memory B cell population in X linked hyper IgM syndrome

Absence of IgD CD27(+) memory B cell population in X linked hyper IgM syndrome

... XHIM B cells (3, 4), indicating that the B cell function in XHIM patients may be ...of memory B cell popula- tions measured by adoptive transfer was grossly impaired by ...

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Follicular lymphoma: too many reminders for a memory B cell

Follicular lymphoma: too many reminders for a memory B cell

... Repeated GC transits carry the risk of genetic instability through repetitive exposure to AID expression (28); there- fore, lymphomas arising from the GC, such as FLs, display a high degree of DNA damage resulting from ...

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Comparison of the Influenza Virus-Specific Effector and Memory B-Cell Responses to Immunization of Children and Adults with Live Attenuated or Inactivated Influenza Virus Vaccines

Comparison of the Influenza Virus-Specific Effector and Memory B-Cell Responses to Immunization of Children and Adults with Live Attenuated or Inactivated Influenza Virus Vaccines

... circulating memory IgG B cells in adults after intranasal im- munization with cold-adapted influenza virus (H3N2) ...antibody-producing cell populations, as we did for the memory B ...

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A unique memory B cell subset correlates with adverse outomes [sic] in human SLE

A unique memory B cell subset correlates with adverse outomes [sic] in human SLE

... hi B cells is associated with increased adverse clinical outcomes, particularly neurological dysfunction and ...3.1). B cells have already been shown to have these roles in autoimmune disease(393), and ...

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Interplay of Il-4, Il-21, and Ifnγ on Memory B Cell Fate Decisions

Interplay of Il-4, Il-21, and Ifnγ on Memory B Cell Fate Decisions

... instruct B cells to adopt various BMEM cell fates via the production of cytokines—specifically IL-4, IL-21 and ...T-BET+ B cell fate. We find that IL-21 or IFNγ directly promote T-BET+ ...

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Dynamics of Memory B-Cell Populations in Blood, Lymph Nodes, and Bone Marrow during Antiretroviral Therapy and Envelope Boosting in Simian Immunodeficiency Virus SIVmac251-Infected Rhesus Macaques

Dynamics of Memory B-Cell Populations in Blood, Lymph Nodes, and Bone Marrow during Antiretroviral Therapy and Envelope Boosting in Simian Immunodeficiency Virus SIVmac251-Infected Rhesus Macaques

... where memory B cells and plas- mablasts (PB) mature in germinal centers following antigen expo- sure (reviewed in reference ...these B-cell subpopulations recirculate in the peripheral blood ...

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Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques

Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques

... the 30-week rest (Figure 1, G–L), but interestingly the plasma blocking activity and neutralization waned more than overall binding activity, although both activities rose after the final boost to levels comparable to ...

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Preexisting subtype immunodominance shapes memory B cell recall response to influenza vaccination

Preexisting subtype immunodominance shapes memory B cell recall response to influenza vaccination

... Viruses and HA antigens. Influenza viruses were obtained through the Influenza Reagents Resource (IRR), BEI Resources, or the Centers for Disease Control and Prevention (CDC) or they were provided by Sanofi Pasteur and ...

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B-Cell Responses to Intramuscular Administration of a Bivalent Virus-Like Particle Human Norovirus Vaccine

B-Cell Responses to Intramuscular Administration of a Bivalent Virus-Like Particle Human Norovirus Vaccine

... to cell attachment factors called histo-blood group antigens (HBGAs) (12, ...17). B-cell responses following experimental infection with NV were recently ...IgG memory B cells revealed ...

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Characterising B cell numbers and memory B cells in HIV infected and uninfected Malawian adults

Characterising B cell numbers and memory B cells in HIV infected and uninfected Malawian adults

... of B cells and memory B cell subpopulation (CD27 + ) were ...The B cells and memory B cell subset were stained with the following monoclonal antibodies conju- gated ...

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Disturbed Homeostasis and Multiple Signaling Defects in the Peripheral Blood B-Cell Compartment of Patients with Severe Chronic Sarcoidosis

Disturbed Homeostasis and Multiple Signaling Defects in the Peripheral Blood B-Cell Compartment of Patients with Severe Chronic Sarcoidosis

... blood B- cell compartments of patients with severe chronic ...the B-cell populations in these patients resembled that found in pSS and CVID and may be related to conditions of bystander ...

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Pathogenic Correlates of Simian Immunodeficiency Virus-Associated B Cell Dysfunction

Pathogenic Correlates of Simian Immunodeficiency Virus-Associated B Cell Dysfunction

... total B cells in progressive species significantly impacts the overall antibody responses, we quantified the total IgG and IgA in PTMs and ...and B), in spite of the B cell loss identified in ...

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