Memory T cells
Increased frequency of CCR4+ and CCR6+ memory T cells including CCR7+CD45RAmed very early memory cells in granulomatosis with polyangiitis (Wegener's)
... culating memory T cells displays T-helper cell 1 (Th1)- type CC chemokine receptor (CCR) 5 and Th2-type CCR3 expression in granulomatosis with polyangiitis (GPA) ...[4]. T cells ...
9
Immunologic response and memory T cells in subjects cured of tegumentary leishmaniasis
... of T cell response was ...of memory T cells ...for memory cells retained in lymph nodes or other tissues migrate to the site of the antigen administration resulting in positive ...
8
Therapeutic Memory T Cells Require Costimulation for Effective Clearance of a Persistent Viral Infection
... ⫹ T cells follow- ing peptide ...⫹ T cells at day 9, and CTLA-4-Fc treatment had no impact on the ability of CD4 ⫹ T cells to produce this cytokine (data not ...antiviral ...
11
Factors that regulate and maintain memory T cells
... Memory T cells are clearly more active than naïve cells, it has therefore been suggested that memory T cells are continuously stimulated to proliferate by extrinsic ...
215
Increased attrition of memory T cells during sepsis requires 2B4
... of memory T cells. Because our data show that memory T cells are more susceptible to sepsis-induced death than naive T cells, in this study we developed a model in ...
12
Resident memory T cells, critical components in tumor immunology
... + T cells was also observed in colorectal and bladder cancers, and was as- sociated with expression of E-cadherin on tumor cells [28, ...to T-cell recruitment within epithelial tumor regions ...
10
The roles of stem cell memory T cells in hematological malignancies
... + T cells expressing Sca-1 (stem cell antigen 1), CD122, and ...of T cells was able to generate and sustain all allogeneic T cell sub- sets in GVHD ...+ T cells were ...
5
Cytomegalovirus infection and progressive differentiation of effector-memory T cells
... p w~l ÿj vfj ÿj vhÿ~n qn hssp |hÿrp g g hn hoj p fj p qoÿqg ÿyz{ s~hip iÿ¦z l p §hÿÿihl l sÿwfÿhÿhp j vhn ÿohfj p |hl ÿqn ÿ~qsp j p |hl ÿfg g hij p oÿvqsj ÿ p wwmop j t ÿyz{ÿl fj hoiÿforÿp j sÿp ...
8
Identification of Pertussis-Specific Effector Memory T Cells in Preschool Children
... lated cells (NS) and cells stimulated with 1 g/ml pokeweed mitogen (PWM) (Sigma) served as negative and positive controls, ...respectively. Cells were stimulated subsequently with PWM, NS, PT, FHA, ...
9
Role of Thymic Output in Regulating CD8 T-Cell Homeostasis during Acute and Chronic Viral Infection
... CD8 T cells play a critical role in control of chronic viral infections with human immunodefi- ciency virus (HIV), Epstein-Barr virus, cytomegalovirus, hep- atitis B virus, and hepatitis C virus (HCV) (15, ...
11
Differential susceptibility of naive and memory CD4+ T cells to the cytopathic effects of infection with human immunodeficiency virus type 1 strain LAI.
... the cells with PHA. Then cells were incubated for 8 to 10 days in culture in the presence of IL-2, and cytopathic effects were assessed by measuring viability and number of each cell ...the cells in ...
9
TCR dependent transformation of mature memory phenotype T cells in mice
... progenitor cells have been implicated in the genesis of select lymphoid ...the cells in which mature lymphoid neoplasms are initiated remains ...peripheral T cell lymphomas using mice in which Snf5, ...
13
A disease associated PTPN22 variant promotes systemic autoimmunity in murine models
... in cells expressing the relevant variant proteins (11), our data strongly support the conclusion that an R-to-W change within the proline-rich region 1 of this phosphatase does not impair protein expression, ...
14
Elite Controllers with Low to Absent Effector CD8+ T Cell Responses Maintain Highly Functional, Broadly Directed Central Memory Responses
... ⴙ T cell responses associated with control of HIV have largely relied on measurement of cytokine secretion by effector T ...central memory T cells, which have not been consistently ...
11
Decreased effector memory CD45RA+ CD62L CD8+ T cells and increased central memory CD45RA CD62L+ CD8+ T cells in peripheral blood of rheumatoid arthritis patients
... of T cells in RA ...these cells out of the peripheral blood, decreased survival of these cells, or blockade in their ...of memory T cells may play an important role in the ...
6
Metabolism, migration and memory in cytotoxic T cells
... directs T cell migration into the efferent ...+ T cells, which have been activated by their cognate antigen presented to them on antigen presenting cells, within the lymph node cease ...
21
Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates
... antigen-specific T cells that have been expanded ex vivo is being actively pursued to treat infections and malignancy in ...The T cell populations that are available for adoptive immunotherapy ...
13
Differences in peripheral myelin antigen-specific T cell responses and T memory subsets in atypical versus typical CIDP
... mononuclear cells; SFU: Spot forming unit; TCM: Central memory T cells; TEM: Effector memory T cells; TEMRA: Terminally differentiated T ...
7
Memory regulatory T cells reside in human skin
... of T cells in human skin are resident in this tissue and are thus non- migratory ...on T cells isolated from ...of memory T cells to secondary lym- phoid organs (17), we ...
11
Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques
... prolonged T cell receptor (TCR) stimulation were shown to progressively redirect CD4 ⫹ T cell development away from a Th1 response during acute infection and toward a Tfh-dominated response during the ...
14