Mesangial cell proliferation
Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis Alpha smooth muscle actin is a marker of mesangial cell proliferation
... Mesangial cell proliferation is common in glomerulonephritis but it is unclear if proliferation is associated with any in vivo alteration in ...whether mesangial of mesangial ...
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Shenhua Tablet inhibits mesangial cell proliferation in rats with chronic anti-Thy-1 nephritis
... and mesangial matrix, which often cause severe glomerulosclerosis and interstitial fibrosis, resulting in irreversible progressive glomerulosclerosis, eventually leading to end-stage renal disease (ESRD) ...
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Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway
... Mesangial cell proliferation has been identified as a mainly contributing factor to glomerulosclerosis, which is typical of diabetic ...of cell proliferation, but the specific role of ...
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Original Article miR-216a-5p promotes mesangial cell proliferation by targeting FoxO1 in diabetic nephropathy
... regulating cell proliferation and migration by targeting the zinc finger E-box-binding homeo- box 1 (ZEB1) ...the proliferation of mesangial cells in DN ...inhibit mesangial cell ...
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Original Article Downregulation of lncRNA NEAT1 inhibits mouse mesangial cell proliferation, fibrosis, and inflammation but promotes apoptosis in diabetic nephropathy
... facilitates cell proliferation and fibrosis ...inhibits cell proliferation, represses expressions of pro-inflammatory cytokines (including monocyte chemoattrac- tant protein-1 (mcp-1), IL-1β ...
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Overexpression of the serpin megsin induces progressive mesangial cell proliferation and expansion
... unknown. Mesangial ECM mass is constantly regulat- ed by its synthesis and degradation (9–13), the latter being determined by the balance existing between pro- teinases and their ...more mesangial matrix, ...
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Infusion of platelet derived growth factor or basic fibroblast growth factor induces selective glomerular mesangial cell proliferation and matrix accumulation in rats
... Mesangial cell (MC) proliferation and extracellular matrix expansion are involved in the pathogenesis of glomerulosclerosis and renal ...MC proliferation and/or matrix ...Glomerular ...
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Inhibition of mesangial cell proliferation by E2F decoy oligodeoxynucleotide in vitro and in vivo
... T cell development and specu- lated that E2F-1 functioned to positively regulate apoptosis and suppressed cell ...stimulated cell proliferation and was oncogenic ...abnormal cell pro- ...
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Transforming growth factor beta Murine glomerular receptors and responses of isolated glomerular cells
... of mesangial matrix are histologic abnormalities which are observed in the course of many progressive glomerular ...endothelial, mesangial, and epithelial cells as well as isolated intact rat glomeruli ...
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Qian Yang Yu Yin Granule containing serum inhibits angiotensin II induced proliferation, reactive oxygen species production, and inflammation in human mesangial cells via an NADPH oxidase 4 dependent pathway
... the proliferation of glomerular mesangial cells and excessive ECM accumu- lation [21,22]; while the key feature of renal fibrosis is the accumulation of myofibroblasts and ECM deposition ...the ...
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An in vitro model of renal inflammation after ischemic oxidative stress injury: nephroprotective effects of a hyaluronan ester with butyric acid on mesangial cells
... by mesangial cell proliferation, inflammation and unbalance between biosynthesis and degradation of extracellular ...of mesangial cell proliferation and matrix expansion may ...
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Essential role of Gas6 for glomerular injury in nephrotoxic nephritis
... Glomerular cell proliferation accompanies a wide variety of renal diseases and is usually associated with matrix expansion that leads to the development of end-stage kidney disease ...for mesangial ...
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Original Article Mitofusin 2 expression in IgA1 induced rat glomerular mesangial cells and IgA nephrology animal model
... glomerular mesangial cell (GMC) proliferation and the expression of Mitofusin 2 (Mfn2), then to further confirm the underlying signal pathway take part in regulating mesangial cell ...
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Effects of chemokines on proliferation and apoptosis of human mesangial cells
... on cell proliferation and ...and mesangial cell proliferation in vitro were not affected by the CCL5/RANTES analogs ...MC proliferation and ...
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Morphine promotes renal pathology in sickle mice
... moderate mesangial prominence, with a mild increase in mesangial cells, slightly increased foot process effacement, prominence of red cell fragments, and electron dense iron deposits in the kidneys ...
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Lovastatin inhibits proliferation of rat mesangial cells
... inhibit proliferation of several cell ...reduced mesangial cellularity and glomerular injury in experimental renal ...and proliferation in rat glomerular mesangial ...arrested ...
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Original Article Triptolide inhibits lipopolysaccharide-induced proliferation, induces apoptosis and causes cell cycle arrest of human mesangial cells in vitro
... Cell proliferation is achieved through the cell cycle. As the cell cycle progresses, cells in G 1 -S phase enter G 2 phase, and mitosis occurs in M pha- ...the cell cycle compared with ...
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Membranoproliferative glomerulonephritis complicating Waldenström’s macroglobulinemia
... decompensation as an extrarenal cause. The only slightly abnormal echocardiographic findings could be explained by the fact that at the time of the examination, cardiac function was already recovering from an acute ...
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Hepatocyte growth factor and renal morphogenesis
... The biological actions of the TGFp family are diverse. They can inhibit or stimulate proliferation, stimulate extracellular matrix formation and promote or inhibit cell migration. TGFpl mRNA is expressed by ...
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Case Report Skin amyloidosis and mesangial proliferation with focal segmental sclerosing glomerulonephritis: a case report
... showed mesangial proliferation with focal segmental sclerosis, which was different with the patholo- gy characteristic of renal ...with mesangial proliferation with focal segmental ...
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