mesenchymal (multipotential) stromal cells
Umbilical cord as a long-term source of activatable mesenchymal stromal cells for immunomodulation
... Mesenchymal stromal cells (MSCs) are used in a variety of clinical trials for a plethora of diseases, due to therapeutic- ally relevant characteristics such as their differentiation po- tential, ...
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Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells
... in mesenchymal stromal cells may be a feedforward mechanism to selectively increase local GC action in these cells during inflammation ...in cells such as hepatocytes, monocytes, and ...
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Bone marrow-derived mesenchymal stromal cells differ in their attachment to fibronectin-derived peptides from term placenta-derived mesenchymal stromal cells
... Multipotent mesenchymal stromal cells (MSCs) have been detected in and isolated from various tissues and ...related mesenchymal cells have been de- scribed in the white pulp of teeth ...
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Decellularized silk fibroin scaffold primed with adipose mesenchymal stromal cells improves wound healing in diabetic mice
... adipose mesenchymal stromal cells; Ad-MSCs- SF: silk fibroin patch cellularized with human adipose-derived mesenchymal stromal cells; ADM: adipocyte differentiation medium; CB: ...
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Effects of senolytic drugs on human mesenchymal stromal cells
... Mesenchymal stromal cells were isolated from the femoral bone marrow of three donors after orthopaedic ...Germany). Cells were cultured at 37 °C, in an atmosphere containing 5% CO 2 , and ...
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Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease
... tissue-derived mesenchymal stromal cells (ASCs) Canine low passage (P2-P5) ASCs from 5 dogs were ob- tained from falciform fat collected from UCD William ...
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Generation of mesenchymal stromal cells from cord blood: evaluation of in vitro quality parameters prior to clinical use
... of mesenchymal stromal cells (MSC) as advanced therapy medicinal products because of their immunomodulatory properties and supportive role in ...
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Isolation and characterization of equine endometrial mesenchymal stromal cells
... treating cells with ...muscle cells from undif- ferentiated MSCs, we assessed the expression of early (ACTA2), intermediate (CNN1), and mature (MYH11) smooth muscle markers [31] in endometrial and BM MSC ...
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Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells
... these cells could be used for the treatment of the end-stage chronic liver ...stem cells, mesenchymal stro- mal cells (MSCs) are the preferred cell type due to their easy isolation, high ...
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Mesenchymal stromal cells in the development and therapy of bronchopulmonary dysplasia
... However, some authors described that treatment with CdM fails to cause long-term effects comparable to whole cell therapy [26], whereas short-term effects of CdM are equal or even superior [21] to an administration of ...
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Unveiling mesenchymal stromal cells’ organizing function in regeneration
... Multilineage potential of adult human mesenchymal stem cells. A., Mesenchymal stem cells in tissue growth and repair[r] ...
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Mesenchymal stromal cells: Biology of adult mesenchymal stem cells: regulation of niche, self renewal and differentiation
... negative cells were better able to aid in the engraftment and survival of HSCs, Stro-1-positive cells were more capable of homing and engrafting to most of the tissues ...by stromal-derived ...
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Are mesenchymal stromal cells immune cells?
... non-haematopoietic cells may not be as sharp as commonly ...stem cells in mice led to the generation of GFP-positive micro- glial and perivascular cells [55], cells that are members of the MSC ...
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Liposomal drug delivery in an in vitro 3D bone marrow model for multiple myeloma
... myeloma cells and supporting cells (mul- tipotent mesenchymal stromal cells [MSCs] and endothelial progenitor cells [EPCs]) within the 3D model, and the effec- tivity of free and ...
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Angiogenic potency evaluation of cell therapy candidates by a novel application of the in vitro aortic ring assay
... Stem cells may have the potential to locally produce an- giogenic factors, self-replicate and/or directly differentiate into new blood vessels [12, ...progenitor cells has mainly focused on endothelial ...
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Perinatal sources of mesenchymal stem cells: Wharton’s jelly, amnion and chorion
... the cells present in the amniotic ...adherent cells isolated from the amniotic fluid without division into E-type, AF-type and F-type ...adherent cells obtained from the amniotic fluid (AF-type) ...
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Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppression
... these cells in unstable plaques com- pared to those from patients with stable coronary ar- tery disease [3, ...of mesenchymal stromal cells (MSCs) showed promise in preclinical studies and ...
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Defined three-dimensional culture conditions mediate efficient induction of definitive endoderm lineage from human umbilical cord Wharton’s jelly mesenchymal stem cells
... clusters of differentiated cells mimicking the formation of embryonic bodies observed with ESCs or iPSCs. Ini- tially, we applied the recently described protocol used to differentiate hESCs and hiPSCs by ...
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Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol
... tissue, and the umbilical cord and (because they appear to be relatively immune privileged) can be subsequently delivered as an allogeneic product to patients [2]. In individual studies using preclinical models of acute ...
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Understanding the regulatory mechanisms of endometrial cells on activities of endometrial mesenchymal stem-like cells during menstruation
... endometrial cells were separated into epithelial and stromal fractions to delineate the cell type that can interact with ...and stromal cells can promote eMSC proliferation and self-renewal by ...
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