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Mesenchymal stem/progenitor cell

Sox9 regulates cell state and activity of embryonic mouse mammary progenitor cells.

Sox9 regulates cell state and activity of embryonic mouse mammary progenitor cells.

... eMPC, embryonic mammary progenitor cell; MSC, mesenchymal stem cell. eMPCs have lactogenic potential[r] ...

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Sex Steroids and Stem Cell Function

Sex Steroids and Stem Cell Function

... marrow mesenchymal stem cells (MSCs) and endothelial progenitor ...endothelial progenitor cells to the ischemic myocardium and enhance neovascularization at the ischemic border ...endothelial ...

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Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis

Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis

... Mesenchymal stem cells (MSCs) can be recruited to the tumor microenvironment and are known as tumor- associated ...cancer stem cells ...stromal progenitor cells (OCSPCs) (epithelial-like and ...

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Mesenchymal stem cells: potential application for the treatment of hepatic cirrhosis

Mesenchymal stem cells: potential application for the treatment of hepatic cirrhosis

... Adipose-derived mesenchymal stem cell; ALD: Alcoholic liver disease; BM-MSC: Bone marrow-derived mesenchymal stem cell; CB-MSC: Cord blood- derived mesenchymal stem ...

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Potential role of stem cells in management of COPD

Potential role of stem cells in management of COPD

... by stem cells from endogenous and exogenous sources is a promising therapeutic ...resident stem and progenitor cell niches within the lung, the contribution of mesenchymal stem ...

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Functional similarities of microRNAs across different types of tissue stem cells in aging

Functional similarities of microRNAs across different types of tissue stem cells in aging

... tissue stem cells (TSCs) contribute to loss of tissue homeostasis, including re- ductions in lymphopoiesis and the long-term repopu- lating abilities of hematopoietic stem/progenitor cells (HSCs) [1, ...

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Human liver mesenchymal stem/progenitor cells inhibit hepatic stellate cell activation: in vitro and in vivo evaluation

Human liver mesenchymal stem/progenitor cells inhibit hepatic stellate cell activation: in vitro and in vivo evaluation

... We also checked whether the same effect could be observed with ADHLSC-conditioned medium. Both ADHLSCs and HSCs (as controls) were seeded separately, at the same initial density as was used in the co-cultures. ...

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Overview of stem cells and their research in burn patients

Overview of stem cells and their research in burn patients

... endogenous stem lity of most adult tissue to regenerate following injury suggests that these mechanisms are not all- powerful and are easily ...marrow stem cell involvement following insult, have ...

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De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas

De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas

... in mesenchymal commitment [4, ...hepatic progenitor cells ...epithelial- mesenchymal transition [13, ...driving progenitor cell reprogramming to replicative, invasive and fibrogenic ...

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Vascular stem cells in diabetic complications: evidence for a role in the pathogenesis and the therapeutic promise

Vascular stem cells in diabetic complications: evidence for a role in the pathogenesis and the therapeutic promise

... other progenitor cell types, MPCs share properties of both stem cells and mature ...of cell surface markers, cell adhesion molecules, and differ- entiation potential (Figure ...this ...

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Iberian pig mesenchymal stem/stromal cells from dermal skin, abdominal and subcutaneous adipose tissues, and peripheral blood: in vitro characterization and migratory properties in inflammation

Iberian pig mesenchymal stem/stromal cells from dermal skin, abdominal and subcutaneous adipose tissues, and peripheral blood: in vitro characterization and migratory properties in inflammation

... In 2006, with the aim of standardization, the Inter- national Society for Cellular Therapy proposed three cri- teria to define the minimal characteristics of MSCs [12]: when maintained in standard culture conditions ...

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Mesenchymal chondroprogenitor cell origin and therapeutic potential

Mesenchymal chondroprogenitor cell origin and therapeutic potential

... Mesenchymal progenitor cells, a multipotent adult stem cell population, have the ability to diff erentiate into cells of connective tissue lineages, including fat, cartilage, bone and muscle, ...

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Endothelial progenitor cells improve the therapeutic effect of mesenchymal stem cell sheets on irradiated bone defect repair in a rat model

Endothelial progenitor cells improve the therapeutic effect of mesenchymal stem cell sheets on irradiated bone defect repair in a rat model

... Cell sheets of BMSC group and +EPC group were incubated with osteogenic medium (10 mM β-glycerolphosphate, 50 µg/ml Vc and 0.1 mM dexa- methasone, Sigma–Aldrich) for 3 or 7 days. ALP produc- tion was tested by ...

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Aberrant perichondrial BMP signaling mediates multiple osteochondromagenesis in mice

Aberrant perichondrial BMP signaling mediates multiple osteochondromagenesis in mice

... a stem cell niche for generating cells of chondrogenic and osteogenic lineages ...express mesenchymal stem cell (MSC) markers, CD44, Sca-1, and Stro-1 (Figure ...

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Novel regenerative therapy for acute kidney injury

Novel regenerative therapy for acute kidney injury

... strategies: cell transplantation and kidney reconstruction. Regarding cell transplantation, several cell types are potential sources, including hematopoietic stem cells, mesenchymal ...

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Is Adipocyte Differentiation the Default Lineage for Mesenchymal Stem/Progenitor Cells after Loss of Mechanical Loading? A Perspective from Space Flight and Model Systems

Is Adipocyte Differentiation the Default Lineage for Mesenchymal Stem/Progenitor Cells after Loss of Mechanical Loading? A Perspective from Space Flight and Model Systems

... The infiltration of tissues by lipids and fat deposits could not only affect tissue function, but also the ability to repair if indeed the move towards such fatty infiltrates is due to loss of regulatory control of the ...

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An improvised one-step sucrose cushion ultracentrifugation method for exosome isolation from culture supernatants of mesenchymal stem cells

An improvised one-step sucrose cushion ultracentrifugation method for exosome isolation from culture supernatants of mesenchymal stem cells

... method in comparison with the UC method where CD63-positive exosomes percentage was 15.1 ± 3% (Fig. 6a). There was no significant increase in CD63-po- sitive exosomal population isolated by either method (Fig. 6b). ...

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Current Status of Stem Cell Therapy for Thromboangiitis Obliterans (Buerger's Disease)

Current Status of Stem Cell Therapy for Thromboangiitis Obliterans (Buerger's Disease)

... Buerger's disease or Thromboangiitis Obliterans (TAO) is a nonatherosclerotic segmental vascular disease which affects small and medium arteries and veins in the upper and lower extremities. Based on pathological ...

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Mesenchymal stem cell infusion for the treatment of neurological sequelae of canine distemper virus: a clinical study

Mesenchymal stem cell infusion for the treatment of neurological sequelae of canine distemper virus: a clinical study

... first cell therapy application, the animals began to present a slight decrease in the sequelae; after 30 days of therapy, there was noticeable improvement and the clinical evolution associated with the ...

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Blood–brain barrier and foetal-onset hydrocephalus, with a view on potential novel treatments beyond managing CSF flow

Blood–brain barrier and foetal-onset hydrocephalus, with a view on potential novel treatments beyond managing CSF flow

... a cell therapy for foetal-onset ...neural stem cells; (2) mesenchymal stem cells; (3) genetically- engineered stem cells; (4) choroid plexus cells and (5) subcommissural organ ...

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