mesenchymal stromal cells (MSCs)
Umbilical cord as a long-term source of activatable mesenchymal stromal cells for immunomodulation
... Mesenchymal stromal cells (MSCs) are used in a variety of clinical trials for a plethora of diseases, due to therapeutic- ally relevant characteristics such as their differentiation po- tential, ...
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Decellularized silk fibroin scaffold primed with adipose mesenchymal stromal cells improves wound healing in diabetic mice
... adipose mesenchymal stromal cells; Ad-MSCs- SF: silk fibroin patch cellularized with human adipose-derived mesenchymal stromal cells; ADM: adipocyte differentiation medium; CB: ...
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Bone marrow-derived mesenchymal stromal cells differ in their attachment to fibronectin-derived peptides from term placenta-derived mesenchymal stromal cells
... Multipotent mesenchymal stromal cells (MSCs) have been detected in and isolated from various tissues and ...related mesenchymal cells have been de- scribed in the white pulp of teeth ...
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Effects of senolytic drugs on human mesenchymal stromal cells
... Background: Senolytic drugs are thought to target senescent cells and might thereby rejuvenate tissues. In fact, such compounds were suggested to increase health and lifespan in various murine aging models. So ...
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Generation of mesenchymal stromal cells from cord blood: evaluation of in vitro quality parameters prior to clinical use
... of mesenchymal stromal cells (MSC) as advanced therapy medicinal products because of their immunomodulatory properties and supportive role in ...
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Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells
... in mesenchymal stromal cells suggests that NF-B inhibitors could usefully inhibit GC synthesis at sites such as muscle and ...immune cells at sites of chronic inflammation, it is more likely ...
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Placenta-derived multipotent mesenchymal stromal cells: a promising potential cell-based therapy for canine inflammatory brain disease
... tissue-derived mesenchymal stromal cells (ASCs) Canine low passage (P2-P5) ASCs from 5 dogs were ob- tained from falciform fat collected from UCD William ...
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Isolation and characterization of equine endometrial mesenchymal stromal cells
... treating cells with ...muscle cells from undif- ferentiated MSCs, we assessed the expression of early (ACTA2), intermediate (CNN1), and mature (MYH11) smooth muscle markers [31] in endometrial and BM MSC ...
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Mesenchymal stromal cells in the development and therapy of bronchopulmonary dysplasia
... these cells in a preventive approach, improvements in lung architecture, pulmonary hypertension, and exercise capacity persisted until adulthood (6 months) of the ...
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Are mesenchymal stromal cells immune cells?
... progenitor cells to ...tissue cells by producing growth factors and matrix ...B cells [10], and inhibit the maturation and function of dendritic cells ...with cells of the im- mune ...
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Mesenchymal stromal cells: Biology of adult mesenchymal stem cells: regulation of niche, self renewal and differentiation
... negative cells were better able to aid in the engraftment and survival of HSCs, Stro-1-positive cells were more capable of homing and engrafting to most of the tissues ...by stromal-derived ...
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Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells
... stellate cells (HSCs; LX-2 line, ...3000 cells/cm 2 . At 50% confluence, the cells were activated with 2% FBS (in KO-DMEM) medium containing 10 ng/ml human TGFβ-1 ...
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Liposomal drug delivery in an in vitro 3D bone marrow model for multiple myeloma
... myeloma cells and supporting cells (mul- tipotent mesenchymal stromal cells [MSCs] and endothelial progenitor cells [EPCs]) within the 3D model, and the effec- tivity of free and ...
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Unveiling mesenchymal stromal cells’ organizing function in regeneration
... Multilineage potential of adult human mesenchymal stem cells. A., Mesenchymal stem cells in tissue growth and repair[r] ...
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Angiogenic potency evaluation of cell therapy candidates by a novel application of the in vitro aortic ring assay
... Stem cells may have the potential to locally produce an- giogenic factors, self-replicate and/or directly differentiate into new blood vessels [12, ...progenitor cells has mainly focused on endothelial ...
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Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppression
... these cells in unstable plaques com- pared to those from patients with stable coronary ar- tery disease [3, ...of mesenchymal stromal cells (MSCs) showed promise in preclinical studies and ...
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Perinatal sources of mesenchymal stem cells: Wharton’s jelly, amnion and chorion
... the cells present in the amniotic ...adherent cells isolated from the amniotic fluid without division into E-type, AF-type and F-type ...adherent cells obtained from the amniotic fluid (AF-type) ...
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Successful integration of transplanted mesenchymal stem cells into the livers of Schistosoma mansoni infected mice
... MSCs may also protect against S. mansoni-induced liver fibrosis by altering the microenvironment of the liver at sites of engraftment. This microenvironment is supposed to be improved in presence of PZQ, since it was ...
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Cryopreservation of canine cardiosphere-derived cells: Implications for clinical application
... canine cells the present study also provides vital translational information to the human ...fresh cells is similar to reports in other species (21,31), conversely the large spheres from cryopreserved ...
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Understanding the regulatory mechanisms of endometrial cells on activities of endometrial mesenchymal stem-like cells during menstruation
... endometrial cells were separated into epithelial and stromal fractions to delineate the cell type that can interact with ...and stromal cells can promote eMSC proliferation and self-renewal by ...
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