metabolic inhibitors
Suppression of gain-of-function mutant p53 with metabolic inhibitors reduces tumor growth in vivo
... the metabolic inhibitors adversely affected the migration of p53-mutant cells, including p53-null cells, although they were less harmful to cells containing both p53- and K-ras ...
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Effect of Metabolic Inhibitors on Growth and Production of L-glutamic Acid by the Mutant Micrococcus glutamicus AB100
... different metabolic inhibitors namely 6-marcaptopurine, 2, 4 dinitrophenol, sodium arsenate, mercuric chloride, sodium arsenite, 2-thiouracil, sodium azide, malonic acid and sodium fluoride were examined on ...
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The Effect of Metabolic Inhibitors on the Cockroach Nerve Muscle Synapse
... The effectiveness with which the various metabolic inhibitors induced changes in both the electrophysiological and ultrastructural characteristics of cockroach nervemuscle synapses suppo[r] ...
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Subcellular injury : ultrastructural changes induced in cultured cells by metabolic inhibitors and other agents
... l X Pages LIGHT MICROSCOPIC TECHNIQUES Phase Contrast Microscopy and Photomicrography 31 Fluorescent Microscopy 31 ELECTRON MICROSCOPIC TECHNIQUES Preparation of Cultured Cells for Elect[r] ...
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METABOLIC CONTROL OF LUMINESCENCE IN THE LUMINOUS ORGANS OF THE TELEOST PORICHTHYS: EFFECTS OF THE METABOLIC INHIBITORS IODOACETIC ACID AND POTASSIUM CYANIDE
... Effects on the light response to KCN The presence of glucose totally inhibited the luminescence induced by KCN; this effect seemed to be mediated by the metabolism of glucose since 2-deo[r] ...
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SOME PARADOXICAL EFFECTS OF METABOLIC INHIBITORS IN ROOT INITIATION AND FLORAL BUD INITITAION
... The most interesting point that has emerged from experiments 1-5 and 8 of this paper is that a pretreatment of the cuttings for 6, 12 or 24 hI" with antimetabolities st[r] ...
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Characterization of Short Term Stress Applied to the Root System by Electrical Impedance Measurement in the First Leaf of Corn (Zea mays L ) and Pumpkin (Cucurbita maxima L )
... We noticed that capacity and resistance evolved in the same direction (both rising) during the increase of nu- trient solution strength from (0.1x) to (2x) and in opposite directions at the highest concentration (4x): ...
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SEQUENTIAL MECHANISMS IN THE ENHANCED ABSORPTION OF VITAMIN B12 BY INTRINSIC FACTOR IN THE RAT
... Because it was shown in dialysis experiments that EDTA neither bound Co60-B12 TABLE V nor affected its dialyzability when bound to rat Effects of metabolic inhibitors on the activity of [r] ...
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Control of Interferon Synthesis: Effect of Diethyl-aminoethyl-Dextran on Induction by Polyinosinic-Polycytidylic Acid
... Moreover, this study suggested that the differences in the response of poly I-poly C-induced interferon production to metabolic inhibitors, such as observed between RKC and some other ty[r] ...
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Activation of Cl secretion during chemical hypoxia by endogenous release of adenosine in intestinal epithelial monolayers
... to metabolic inhibitors is related to the endogenous release of adenosine into the extracellular space in quantities sufficient to interact locally with stimulatory adenosine ...a metabolic feedback ...
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Genomic characterization of the virus causing infectious salmon anemia in Atlantic salmon (Salmo salar L.): an orthomyxo-like virus in a teleost.
... i ISAV replication was not affected after the addition of metabolic inhibitors BrdU and IdU to the cell culture medium, ii radioactive RNA was adsorbed to magnetic beads in experiments w[r] ...
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Coxsackievirus A24 Variant Uses Sialic Acid-Containing O-Linked Glycoconjugates as Cellular Receptors on Human Ocular Cells
... or metabolic inhibitors of de novo glycosylation suggested that the receptor(s) used by CVA24v are constituted by sialylated O-linked glycans that are linked to one or more cell surface proteins but not to ...
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Regulation of Expression of Cloned Bacteriophage T4 Late Gene 23
... The effect that metabolic inhibitors of DNA replication exert on expression of chromosomal late genes and cloned gene 23 was also examined in the denA:denB:56:unf genetic background.. Ef[r] ...
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Metabolic engineering of Acinetobacter baylyi ADP1 for removal of Clostridium butyricum growth inhibitors produced from lignocellulosic hydrolysates
... of inhibitors, ...aromatic inhibitors, such as 4-hydroxybenzoate, vanillate, ferulate, protocatechuate, and benzoate [34], it is unable of growing on furfural or 5-(hydroxymethyl)furfural as sole carbon ...
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Enhancing central noradrenergic function in depression: is there still a place for a new antidepressant?
... oxidase inhibitors (MAOIs), serotonin-noradrenaline reuptake inhibitors (SNRIs), selective noradrenaline reuptake inhibitors (NRIs), the noradrenergic and specific serotonergic antidepressant (NaSSA) ...
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Non-Hepatic Adverse Effects of Antiretroviral Therapy for HIV Treatment and Care
... Transcriptase Inhibitors. Protease Inhibitors: Most ART regimens are boosted with the use of ritonavir, although some patients cannot tolerate ritonavir because of its adverse gastrointestinal ...
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Genome scale network model of metabolism and histone acetylation reveals metabolic dependencies of histone deacetylase inhibitors
... In FBA, an optimal metabolic flux state is determined that maximizes an objective (usually the biomass). We used the biomass composition from Shlomi et al. [70] for the growth objective function. The biomass ...
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Mitoketoscins : novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs)
... critical metabolic enzymes implicated in this process are OXCT1 and ACAT1, which are both mitochondrial ...as metabolic “tumor ...by metabolic flux ...mitochondrial inhibitors are partially ...
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Progress of small molecular inhibitors in the development of anti-influenza virus agents
... NA inhibitors are currently the most popular targets of antiviral research (Oseltamivir and Zanamivir are effective against amantadane resistant ...NA inhibitors oseltamivir and Zanamivir is also limited ...
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Disrupted flow sensing impairs hydrodynamic performance and increases the metabolic cost of swimming in the yellowtail kingfish, Seriola lalandi
... the metabolic benefits of a lowered cost of locomotion for a given swimming speed, and the complex interaction of boundary layers, drag and thrust production, it seems reasonable that active flow sensing by fish ...
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