metabolomics data
COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access
... raw data available to the interested research community has clear benefits to the transparency and trustworthiness of those scientific ...their data deposition, depending on their preferred ...protect ...
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PhenoMeNal: processing and analysis of metabolomics data in the cloud
... interoperable metabolomics data analysis platforms into the ...shareable metabolomics data analysis platforms that are interfaced through standard data formats, representative datasets, ...
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Normalizing untargeted periconceptional urinary metabolomics data : a comparison of approaches
... urinary metabolomics data generated from our cohort may not be generalizable to all periconceptional ...of data collected by mass spectrometry have distinct advantages in large cohort ...
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Influence of missing values substitutes on multivariate analysis of metabolomics data
... based metabolomics data, both for unsupervised and supervised ...in data pre-processing, as has been suggested previously in the literature [7], to which special consideration should be ...when ...
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Fusing metabolomics data sets with heterogeneous measurement errors
... fused metabolomics data from different platforms however is not straight- ...multivariate data analysis methods, and also SCDA, are limited by the fact that homoscedastic error is ...In ...
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A Comparison of Various Normalization Methods for LC/MS Metabolomics Data
... In metabolomics data, like other -omics data, normalization is an important part of the data ...in metabolomics data sets, we compare these methods to two methods that make ...
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COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access
... raw data available to the interested research community has clear benefits to the transparency and trustworthiness of those scientific ...their data deposition, depending on their preferred ...protect ...
11
Biomarker and pathway analyses of urine metabolomics in dairy cows when corn stover replaces alfalfa hay
... Background: Alfalfa hay and corn stover are different type of forages which can significantly impact a cow ’ s lactation performance, but the underlying metabolic mechanism has been poorly studied. We used biomarker and ...
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Metabolomics Analysis Identifies Sphingolipids as Key Signaling Moieties in Appressorium Morphogenesis and Function in Magnaporthe oryzae
... untargeted metabolomics data were initially explored via principal-component analysis (PCA), which revealed that the 42 samples (6 replicates for each of the 7 time points) were clustered into seven groups ...
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Epigenetic findings in periodontitis in UK twins: a cross-sectional study
... each data point was scaled ...This metabolomics data was available in 472 (tooth mobility) and 506 (gingival bleeding) individuals for whom phenotype and whole Table 1 Samples used in blood, buccal, ...
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Plasma disturbance of phospholipid metabolism in major depressive disorder by integration of proteomics and metabolomics
... Introduction: Major depressive disorder (MDD) is a highly prevalent mental disorder affecting millions of people worldwide. However, a clear causative etiology of MDD remains unknown. In this study, we aimed to identify ...
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A Tool to Encourage Minimum Reporting Guideline Uptake for Data Analysis in Metabolomics
... the data analysis part of the ...multivariate data analysis/high dimensional data analysis/omics data analysis/supervised data ...for data analysis reporting, but it does ...
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Novel personalized pathway-based metabolomics models reveal key metabolic pathways for breast cancer diagnosis
... both data sets, support- ing the excellence of the early diagnostic model ...the metabolomics data and TCGA RNA-Seq ...both metabolomics and RNA-Seq data sets (Additional file 3: Table ...
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Evaluation of O2PLS in Omics data integration
... the metabolomics data we find the VLDL subgroup together with the HDL subgroup to be important for the joint variation in the metabolomics data ...simultaneous data analysis approach ...
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Toward collaborative open data science in metabolomics using Jupyter Notebooks and cloud computing
... current data science frameworks relevant to the metabolomics commu- nity, corresponding barriers to achieving open science, and finally a practical solution in the form of the computational lab notebook, ...
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Label-free data standardization for clinical metabolomics
... the metabolomics technologies and the limited number of commercially available chemical standards required to build calibration ...of metabolomics tests. To this end, an algorithm that converts ...
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Metabolomics of biofluids : from analytical tools to data interpretation
... generated data can not be directly used for the statistical analysis without prior ...for metabolomics data independently of whether it is based on nuclear magnetic resonance (NMR) or hyphenated MS ...
176
Metabolomics in Medicine
... integrated data acquisition, data evaluation, and statistical building ...solution. Metabolomics technology has mainly developed in plants, which are easier to study compared to ...
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Quantitative in vivo phosphoproteomics reveals reversible signaling processes during nitrogen starvation and recovery in the biofuel model organism Chlamydomonas reinhardtii
... Further data processing was done with the Perseus ...Phosphoproteomics data were log2-transformed, and the following filtered steps were applied: only phosphopeptides belonging to cat- egory I (localization ...
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Integrated omics-based pathway analyses uncover CYP epoxygenase-associated networks as theranostic targets for metastatic triple negative breast cancer
... oxylipin metabolomics, immunoreac- tivity and gene expression analyses, we performed a series of in vitro functional assays using human-derived breast cancer cell lines representative of Her2-overexpressing (ER ...
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