Metanephric mesenchyme
COUP TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival
... induces metanephric mesenchyme fate in kidney progenitor ...the metanephric mesenchyme (Sajithlal et ...committed metanephric mesenchyme and subsequent induction of ureteric bud ...
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Gene expression profiles in developing nephrons using Lim1 metanephric mesenchyme-specific conditional mutant mice
... polarization, mesenchyme to epi- thelia transformation, branching morphogenesis, angio- genesis, apoptosis, proximal-distal segmentation and the differentiation of several interesting cell ...
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Single cell dissection of early kidney development: multilineage priming
... the metanephric mesenchyme consists of cells that will contribute to the stromal, nephron and vascular components of the ...E11.5 metanephric mesenchyme, ...E11.5 metanephric ...
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BMPs and BMP receptors in mouse metanephric development: in vivo and in vitro studies
... the metanephric mesenchyme, and epithelialisation of mes- enchyme cells is dependent on signals from cells at the tips of the ureteric ...the metanephric mesenchyme and reduced ...
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Gremlin mediated BMP antagonism induces the epithelial mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis
... metanephric mesenchyme, it induces condensation and nephrogenesis through reciprocal interactions (Saxén, ...condensing metanephric mesenchyme (Hellmich et ...for metanephric ...
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Alk3 controls nephron number and androgen production via lineage specific effects in intermediate mesoderm
... the metanephric mesenchyme (Grobstein, 1956; Saxen and Sariola, ...the metanephric mesenchyme express Osr1, which is required for the differentiation of the derivative renal stromal and ...
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Sall1 dependent signals affect Wnt signaling and ureter tip fate to initiate kidney development
... A crucial step in kidney development is the interaction between the outgrown ureteric bud (ub) and the metanephric mesenchyme (mm). Reciprocal signaling triggers the ub to initiate its first T- branch and ...
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Unilateral hypoplastic kidney - a novel highly penetrant feature of familial juvenile hyperuricaemic nephropathy
... Nephrourogenesis commences at four weeks of gesta- tion, when signals from metanephric mesenchyme (MM) initiate the formation of the ureteric bud (UB) from the nearby Wolffian duct. Contact and interactions ...
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BMP7 promotes proliferation of nephron progenitor cells via a JNK dependent mechanism
... within metanephric mesenchyme was significantly reduced in Bmp7-null kidneys, supporting the in vitro findings that BMP7 functions as a proliferative growth factor ...cap mesenchyme in the Bmp7-null ...
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Multipotent stem cells in the Malpighian tubules of adult Drosophila melanogaster
... The mammalian kidney develops from the intermediate mesoderm and proceeds through three successive stages of development, each marked by the development of a more advanced pair of organs: the pronephros, the mesonephros ...
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Novel clinicopathological and molecular characterization of metanephric adenoma: a study of 28 cases
... In summary, the somatic mutation spectrum and mutation load (14.5/Mb) of MA was quite different from several other common types of renal carcinoma, such as renal clear cell carcin- oma, [r] ...
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Case Report Metanephric adenoma: two cases report and review of the literature
... In 1979, Bove firstly raised the term ‘meta- nephric adenoma’ which origins from primitive epithelium of the proximal nephron [1]. In 1998, the World Health Organization (WHO) histologi- cal type of renal tumors ...
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Stromal mesenchyme cell genes of the human prostate and bladder
... CD phenotypes of prostate stroma vs. bladder stroma Almost all the constituent cell types of the prostate and bladder were identified by their particular complement of CD molecules. Overall, the stromal mesenchyme ...
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Mannose induced dysmorphogenesis of metanephric kidney Role of proteoglycans and adenosine triphosphate
... Because various fetal anomalies are seen in diabetic offspring, we examined the effects of sugars on proteoglycans (PGs): extracellular matrix (ECM) macromolecules modulating morphogenesis. 13-d-old mouse ...
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Alcohol promotes in vitro chondrogenesis in embryonic facial mesenchyme
... ated signal transduction events (Littleton, 1989). Ethanol exposure can directly or indirectly modulate interactions between signaling ligands and their receptors (Henderson et al., 1989; Resnicoff et al., 1993; Tomono ...
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Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4enhancer
... Figure 3 Dynamic expression profile of Tbx4-rtTA-mediated Tet-On targeting system shown by the triple transgenic reporter (Tbx4-rtTA/TetO-Cre/mT-mG). (A) Tbx4-rtTA-mediated Tet-On system targeted lung mesenchyme ...
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Stimulation of tenascin expression in mesenchyme by epithelial mesenchymal interactions
... Inl ,I Ue\ Hinl 33 71 7Q (1989) 71 Stimulation of tenascin expression in mesenchyme by epithelial mesenchymal interactions PETER EKBLOM and EN NO AUFDERHEIDE Friedrich M,escher Laboraronum der Max Pla[.] ...
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Original Article Immunohistochemical phenotype and molecular pathological characteristics of metanephric adenoma
... Metanephric adenoma ( MA) is an uncommon renal benign tumor, derived from the renal residual organization during embryonic devel- opment [1]. Named by Brisigotti since 1992 [2], few cases are found in the ...
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Hoxa2 downregulates Six2 in the neural crest derived mesenchyme
... The identified Six2 promoter region recapitulated the expression of the endogenous gene in the first arch; Hoxa2 blocked Six2 expression in an equivalent domain in the second branchial arch. To test if this promoter ...
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Estrogen modulates mesenchyme epidermis interactions in the adult nipple
... Generally, epithelial specialization is thought to require inductive signals from the underlying connective tissue (Dhouailly et al., 1998). For example, seminal experiments conducted by the Billingham group found that ...
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