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micro RNAs

Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation

Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation

... Micro RNAs are key negative regulating factors that influence the timing of organogenesis, apoptosis, proliferation, and differentiation [16, 17], and some play important roles in the regulation of HF ...

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The Circulating Micro-RNAs (−122, −34a and −99a) as Predictive Biomarkers for Non-Alcoholic Fatty Liver Diseases

<p>The Circulating Micro-RNAs (&minus;122, &minus;34a and &minus;99a) as Predictive Biomarkers for Non-Alcoholic Fatty Liver Diseases</p>

... The reverse transcription real-time PCR (RT-PCR) method was used for mi-RNA expression. In brief, total RNA (200 ng) was used for three mi-RNAs: mi-RNA-122, mi-RNA-34a, and mi-RNA-99a using TaqManmi-RNA assays ...

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Role of micro-RNAs in drug resistance of multiple myeloma

Role of micro-RNAs in drug resistance of multiple myeloma

... of micro- RNAs (miRNAs) in the study of cancer biology and pathogenesis in recent years has revolutionized therapy in this field and particularly opened new windows to further understanding of tumor drug ...

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Non-randomness distribution of micro-RNAs on human chromosomes

Non-randomness distribution of micro-RNAs on human chromosomes

... non-coding RNAs such as micro-RNAs (miR- NAs), small nucleolar RNAs (snoRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs) exist in human genome [1, ...

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Current understanding on micro RNAs and its regulation in response to Mycobacterial infections

Current understanding on micro RNAs and its regulation in response to Mycobacterial infections

... Additionally, differential miRNA regulation was also reported recently in response to high virulent Myco- bacteria (M. tuberculosis) as compared to low virulent (M. smegmatis) in infected human macrophages [49]. ...

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Micro-RNAs and Their Roles in Breast Cancer Pathogenesis; An Updated Review Article

Micro-RNAs and Their Roles in Breast Cancer Pathogenesis; An Updated Review Article

... Micro-RNAs (miRNAs) are small molecules that modulate the translation of target mRNA through binding to these molecules. In cancer, the expression of oncogenes and suppressors are increased and decreased, ...

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Extra cellular release and blood diffusion of BART viral micro RNAs produced by EBV infected nasopharyngeal carcinoma cells

Extra cellular release and blood diffusion of BART viral micro RNAs produced by EBV infected nasopharyngeal carcinoma cells

... strand RNAs of short size (20 to 25 nt) which result from maturation of large pri- mary transcripts and have important regulatory func- tions in gene ...of micro- RNAs is facilitated by various ...

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Micro-RNAs as Potential New Molecular Biomarkers in Oncology: Have They Reached Relevance for the Clinical Imaging Sciences?

Micro-RNAs as Potential New Molecular Biomarkers in Oncology: Have They Reached Relevance for the Clinical Imaging Sciences?

... MiRNAs were first discovered in 1993. They are small single stranded RNA (ssRNA) molecules of 21-23 nucleotides in length, and it was long specu- lated that they are just degraded RNA fragments or non-translated small ...

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Expression of micro-RNAs and genes related to angiogenesis in ccRCC and associations with tumor characteristics

Expression of micro-RNAs and genes related to angiogenesis in ccRCC and associations with tumor characteristics

... The study comprised the analysis of specimens from 56 patients diagnosed with ccRCC who were surgically treated by radical or partial nephrectomy at Hospital das Clinicas of University of Sao Paulo Medical School be- ...

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Micro-RNAs, New performers in multiple myeloma bone marrow microenvironment

Micro-RNAs, New performers in multiple myeloma bone marrow microenvironment

... miRs belong to a class of small non-coding RNAs (22 – 25 nt. in length) which repress the expression of their target genes at translational level by binding to 3 ′ UTR through partial sequence complementarity ...

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Extracellular Micro RNAs in Health and Disease: Basic Science, Biogenesis and Release

Extracellular Micro RNAs in Health and Disease: Basic Science, Biogenesis and Release

... extracellular RNAs (exRNAs), have been well correlated with disease or injurious conditions [13]-[16], sug- gesting that these extracellular miRNAs can be served as diagnostic and prognostic ...

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HIV 1 encoded candidate micro RNAs and their cellular targets

HIV 1 encoded candidate micro RNAs and their cellular targets

... Here, we introduce the concept that the HIV genome could reasonably encode 5 candidate pre-miRNAs. We further suggest that a large number of cellular transcripts could potentially be targeted if these 5 pre-miRNAs were ...

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ROLE OF MICRO RNAS AND ITS REGULATION FOR MYCOBACTERIAL INFECTIONS

ROLE OF MICRO RNAS AND ITS REGULATION FOR MYCOBACTERIAL INFECTIONS

... noncoding RNAs is microRNAs (miRNAs), a group of regulatory RNAs of 19–22 nucleotides involved in control of gene expression at the post-transcriptional ...

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Epstein-Barr Virus BHRF1 Micro- and Stable RNAs during Latency III and after Induction of Replication

Epstein-Barr Virus BHRF1 Micro- and Stable RNAs during Latency III and after Induction of Replication

... BHRF1 micro-RNAs (miRNAs), which are encoded in an intron of most EBNA RNAs (11, ...small RNAs (EBER1 and -2), BamHI A rightward transcripts (BARTs) (7, 15, 22, 37, 54, 56, 58), and 24 BART ...

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Databases and resources for human small non-coding RNAs

Databases and resources for human small non-coding RNAs

... Recent advances in high-throughput sequencing have facilitated the genome-wide studies of small non-coding RNAs (sRNAs). Numerous studies have highlighted the role of various classes of sRNAs at different levels ...

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Integrative analysis of lncRNAs and miRNAs with coding RNAs associated with ceRNA crosstalk network in triple negative breast cancer

Integrative analysis of lncRNAs and miRNAs with coding RNAs associated with ceRNA crosstalk network in triple negative breast cancer

... non-coding RNAs (lncRNAs), which can act as competing endogenous RNAs (ceR- NAs) and suppress miRNA functions involved in post-transcriptional regulatory networks in the ...expressed micro ...

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Long Noncoding RNAs in Diffuse Large B-Cell Lymphoma: Current Advances and Perspectives

<p>Long Noncoding RNAs in Diffuse Large B-Cell Lymphoma: Current Advances and Perspectives</p>

... noncoding RNAs (ncRNAs) in recent decades has revealed new prospects for tumor ...noncoding RNAs (lncRNAs), microRNAs (miRNAs) and circular RNAs, are RNA transcripts of variable length that are not ...

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Long noncoding RNAs coordinate functions between mitochondria and the nucleus

Long noncoding RNAs coordinate functions between mitochondria and the nucleus

... nuclear-encoded RNAs in mitochon- dria have potentially diverse import pathways, and the details of four RNA import mechanisms of mitochon- dria have been ...

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Decoding Noncoding RNAs: Role of MicroRNAs and Long Noncoding RNAs in Ocular Neovascularization

Decoding Noncoding RNAs: Role of MicroRNAs and Long Noncoding RNAs in Ocular Neovascularization

... small RNAs [27-29]; some lncRNAs are transcribed from the intronic regions of human genome, processed at the consensus sequences close to 5’ splice site and branchpoint, and persist as circular intronic ...

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Original Article Long non-coding RNA H19 promotes colorectal cancer metastasis via negative modulation of miR-148b

Original Article Long non-coding RNA H19 promotes colorectal cancer metastasis via negative modulation of miR-148b

... Non-coding RNAs play a vital role in carcinogen- esis, cancer development and cancer metasta- sis [13]. The studies on non-coding RNA provide new insights into the biology of cancers. Over the past decade, miRNAs ...

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