MiR-125a-5p
miR-125a-5p ameliorates hepatic glycolipid metabolism disorder in type 2 diabetes mellitus through targeting of STAT3
... of miR-125a-5p in T2DM and other metabolic ...the miR-125a level was reduced in the liver of spontaneously diabetic Goto Kakizaki (GK) rats compared with Brown-Norway (BN) rats [43], ...
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miR-125a-5p suppresses colorectal cancer progression by targeting VEGFA
... that miR-125a-5p suppressed the proliferation, migration, and invasion of CRC cells in vitro, we further explored the influence of miR-125a-5p on tumor growth and metastasis in ...
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miR-125a-5p is a prognostic biomarker that targets HDAC4 to suppress breast tumorigenesis
... of miR-125a-5p induces apoptosis through p53 activation in lung cancer ...inhibiting miR- 125a-5p increases MMP11 and VEGFA protein expression, while restoring ...
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Original Article Serum miR-125a-5p, miR-145 and miR-146a as diagnostic biomarkers in non-small cell lung cancer
... circulating miR-125a-5p, miR-145 and miR-146a could be used as biomarkers for the diagnosis of NSCLC through measuring their expression and assess their relationship with clinical ...
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miR-125a-5p post-transcriptionally suppresses GALNT7 to inhibit proliferation and invasion in cervical cancer cells via the EGFR/PI3K/AKT pathway
... of miR-125a-5p in progression of cervical ...of miR-125a-5p and GALNT7 in cervical cancer tissues and cell ...the miR-125a-5p mimic, ...
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<p>Upregulation of TRIAP1 by the lncRNA MFI2-AS1/miR-125a-5p Axis Promotes Thyroid Cancer Tumorigenesis</p>
... sponges miR-151-3p to upregulate RAB22A and promote osteosarcoma ...biting miR-340. 23 MFI2-AS1 was previously shown to sponge miR-574-5p in ...for miR-125a-5p in thyroid ...
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<p>The lncRNA HOXA11-AS regulates Rab3D expression by sponging miR-125a-5p promoting metastasis of osteosarcoma</p>
... of miR-125a-5p was negatively cor- related with that of HOXA11-AS and ...while miR-125a-5p had a negative regulatory effect on the invasiveness of OS cell ...
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<p>The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro</p>
... on miR-125a-5p (Figure ...with miR-125a-5p in U251 cells (Figure 3B and ...of miR-125a-5p, the same negative relationship was found between BCYRN1 and ...
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<p>miR-125a-5p inhibits colorectal cancer cell epithelial–mesenchymal transition, invasion and migration by targeting TAZ</p>
... Total RNA was extracted from LoVo and SW480 cells using Trizol reagent (Invitrogen, USA) and miRNeasy extraction kit (Qiagen; Germantown, MD) according to the manufacturer ’ s instructions. Single-stranded cDNA was ...
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Circ_0001667 promotes breast cancer cell proliferation and survival via Hippo signal pathway by regulating TAZ
... of miR-125a-5p by Targetscan and dual lucif- erase assay ...reversely miR-125a-5p suppressed the expression level of ...between miR-125a-5p and ...
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MicroRNA-125a-5p modulates human cervical carcinoma proliferation and migration by targeting ABL2
... lentivirus mir-125-mimic to overexpress mir-125a-5p for 6 ...between mir-125a-5p and aBl2 ...nullified miR-125a-5p binding site was also created ...
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MicroRNA-125a-5p regulates cancer cell proliferation and migration through NAIF1 in prostate carcinoma
... the miR-125a-5p binding site on NAIF1 3 ′ -UTR was modified by a Site- Directed Mutagenesis Kit (SBS Genetech, Beijing, People’s Republic of ...synthesized miR-125a-5p ...
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<p>Overexpression of miR-671-5p indicates a poor prognosis in colon cancer and accelerates proliferation, migration, and invasion of colon cancer cells</p>
... of miR-671-5p using SYBR Green Real-Time PCR Master Mix (Thermo Fisher Scienti fi c, ...of miR-671-5p was calculated using 2 −ΔΔCt method with U6 used as an internal ...
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Maternal obesity alters C19MC microRNAs expression profile in fetal umbilical cord blood
... Ghaffari et al. reported that there is no difference in the fetal umbilical cord blood miRNA expression and placental miRNA expression in maternal obesity [42, 43]. Juracek performed TaqMan microarrays to identify five ...
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Original Article The role of miR-211-5p in the viability, apoptosis, and migration of chondrocytes in osteoarthritis
... the miR-211-5p mimic was seen to significantly promote chon- drocyte viability compared to the miR-NC ...the miR-211-5p mimic had the potential to reverse the inhibito- ry effect of ...
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Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway
... through miR-423-5p to regulate the Rho/Rac pathway. miR-423-5p inhibited the expression of RAC1 , RHOC , LASP1 , and RAB11B and increased that of other molecules, including RAB10 , RAB11A , ...
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<p>MicroRNA-497-5p Induces Cell Cycle Arrest Of Cervical Cancer Cells In S Phase By Targeting CBX4</p>
... MicroRNA (miRNA or miR) is a class of non-coding RNA with 14 – 24 nucleotides. 1 It is reported that abnormal expression of miRNA is associated with tumorigenesis. 1–3 Some miRNA molecules can induce tumorigenesis ...
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<p>LncRNA-MALAT1 regulates proliferation and apoptosis of ovarian cancer cells by targeting miR-503-5p</p>
... and miR-503-5p inhibition using MTT assay in both SKVO3 and OVCAR3 ...and miR-503-5p inhibition on cell proliferation on SKVO3 and OVCAR3 cells ...and miR-503-5p ...
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Original Article MicroRNA-380-5p inhibits migration and invasion of ovarian cancer SKOV3 cells and regulates epithelial-mesenchymal transition factors
... ple, miR-200c regulates zinc finger E-box bind- ing homeobox 2 (ZEB2) expression to suppress invasion of ovarian cancer ES-2 cells ...[12]. miR- 22 suppresses migration and invasion abilities of SKOV3 cells ...
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The tumor suppressor miR-138-5p targets PD-L1 in colorectal cancer
... of miR-138-5p in human colorectal cancer (CRC) development. miR-138-5p was frequently downregulated in CRC tissues and was associated with advanced clinical stage, lymph node metastasis and ...
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