Mir 145 5p
KCNQ1OT1 aggravates cell proliferation and migration in bladder cancer through modulating miR-145-5p/PCBP2 axis
... of miR-145-5p most significantly ...selected miR-145-5p as candidate miRNA for present ...of miR-145-5p in BC tissue and cell lines was detected by qRT-PCR ...
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<p>miR-145-5p Regulates the Proliferation, Migration and Invasion in Cervical Carcinoma by Targeting KLF5</p>
... follows: miR- 145-5p (F: 5 ʹ -CTCACGGTCCAGTTCCCA-3 ʹ ; R: 5 ʹ -ACC TCAAGAACAGTATTTCCAGG-3 ʹ ); U6 (F: 5 ʹ -GCTTCGG CAGCACATATACTAAAAT-3 ʹ ; R:5 ʹ -CGCTTCACGAATT TGCGTGTCAT-3 ʹ ); KLF5 (F: 5 ʹ ...
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Original Article Lower miR-145-5p expression and its potential pathways in hepatocellular carcinoma: a bioinformatics analysis with RNA-seq and microarray data
... that miR-145-5p expressed markedly lower in HCC tissue than that in non- cancerous liver tissue ...of miR-145-5p was consistently lower in HCC tissues than that in both of adja- ...
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MiR-145-5p suppresses the proliferation, migration and invasion of gastric cancer epithelial cells via the ANGPT2/NOD_LIKE_RECEPTOR axis
... of miR-145-5p was found to be down-regulated in GC cells, while ANGPT2 was ...between miR-145-5p and ANGPT2, qRT-PCR and western blot were carried ...the ...
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CircZNF609 promotes breast cancer cell growth, migration, and invasion by elevating p70S6K1 via sponging miR-145-5p
... of miR-145-5p to elevate p70S6K1 expression. Moreover, miR- 145-5p overexpression or p70S6K1 knockdown abrogated the oncogenic effects of circZNF609 in breast ...and ...
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Original Article Diagnostic and prognostic significance of serum miR-145-5p expression in glioblastoma
... All statistical analyses were implemented using MedCalc V15.2 (MedCalc Software, Ostend, Belgium). Statistical comparison between gro- ups was performed with Kruskal-Wallis test. Chi-square analysis was conducted to ...
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Dual-strand tumor-suppressor microRNA-145 miR-145-5p and miR-145-3p ) coordinately targeted MTDH in lung squamous cell carcinoma
... that miR-145-5p (the guide strand) functions as a tumor suppressor in several types of ...of miR-145- 3p (the passenger strand) on cancer cells is still ...of ...
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circPTN sponges miR-145-5p/miR-330-5p to promote proliferation and stemness in glioma
... sponging miR-145-5p and miR-330-5p; we verified this using dual-luciferase reporter assays and biotin-la- beled RNA pull-down ...of miR-145- ...in ...
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Epigenetic silencing of miR-145-5p contributes to brain metastasis
... that miR-145-5p down-regulation occurs early during tumorigenesis and it confers high metastatic ...that miR-145-5p suppresses known target mRNAs, such as those encoding the ...
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Over-expression of the miR-483-3p overcomes the miR-145/TP53 pro-apoptotic loop in hepatocellular carcinoma.
... between miR-483-3p and miR-145-5p, we took in consideration the ratio of the relative expressions of these two miRNAs (miR-483/miR-145) (Figure ...the ...
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MicroRNA-145-5p inhibits gastric cancer invasiveness through targeting N-cadherin and ZEB2 to suppress epithelial–mesenchymal transition
... Total RNA was isolated from the tissue samples and GC cells using TRIzol reagent (Thermo Fisher Scientific). RNA concentration and purity were determined using Nanodrop 2000 (Thermo Fisher Scientific). Reverse ...
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MiR-876-5p modulates head and neck squamous cell carcinoma metastasis and invasion by targeting vimentin
... example, miR-30a and miR-934 have been reported to be significantly upregulated in alcohol-associated HNSCC ...the miR-124 expression level was ...that miR-422a was significantly decreased in ...
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Multiple microRNAs regulate human FOXP2 gene expression by targeting sequences in its 3' untranslated region
... let-7a, miR-9, and miR-129-5p in the human FOXP2 3 ′ ...let-7a, miR-9, and miR-129-5p in the FOXP2 3 ′ UTR abolished the repressive effects of these miRNAs in luciferase reporter ...
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MicroRNA expression profile in exosome discriminates extremely severe infections from mild infections for hand, foot and mouth disease
... Further investigate the possible functions of miRNAs through GO terms and KEGG pathway annotation. The putative targets for these miRNAs were mainly involved in such as MAPK signalling pathway related to potential ...
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Screening miRNAs for early diagnosis of colorectal cancer by small RNA deep sequencing and evaluation in a Chinese patient population
... of miR-18a-5p and miR-21-3p or downregulation of miR-133a-3p in adenoma and cancer tissues may serve as an index for early screening of colorectal ...as miR-135b-5p, ...
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P< 0.05). Also, the group D had lower cell proportion and cell apoptosis rate than the
... that miR-145 overexpression occurred in OA [20], which also verified the other ...of miR-145 were obtained through cell ...of miR-145 significantly decreased but increased in ...
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<p>Long noncoding RNA Linc00460 promotes breast cancer progression by regulating the miR-489-5p/FGF7/AKT axis</p>
... to miR-489-5p to increase FGF7 expression and activates downstream AKT ...Predicted miR-489-5p-binding site on the 3 ʹ UTR of FGF7 ...with miR-489-5p mimics, ...
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Original Article MicroRNA-380-5p inhibits migration and invasion of ovarian cancer SKOV3 cells and regulates epithelial-mesenchymal transition factors
... for miR-380-5p (forward: 5’-ACACT CCAGC TGGGT GGTTG GACCA TAGAA C-3’ and reverse: 5’-TGGTG TCGTG GAGTC G-3’) or RAC1 (forward: 5’-CACGA TCGAG AAACT GAAGG A-3’ and reverse: 5’-AGCAG GCATT TTCTC TTCCT ...of ...
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<p>LncRNA-MALAT1 regulates proliferation and apoptosis of ovarian cancer cells by targeting miR-503-5p</p>
... 35 miR-200s/ZEB2, 36 ATM- CHK2, 37 and ...Moreover, miR-9 secreted from tumor cells can activate JAK-STAT3 signaling path- way by suppressing the expression of SOCS5, conse- quently leading to deterioration ...
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The tumor suppressor miR-138-5p targets PD-L1 in colorectal cancer
... that miR-138 might be a tumor suppressor in some cancers, including colorectal cancer, ovarian cancer, head and neck squamous cell carcinoma, nasopharyngeal carcinoma and pancreatic cancer [8, 24, ...of ...
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