miR-15b
Original Article The mechanism of miR-15b inhibiting nasopharyngeal carcinoma cell proliferation
... biomarkers. MiR-15b abnormally expressed in tumor and could be treated as ...of miR-15b in NPC occurrence and ...with miR-15b mimics or inhibitor. Real time PCR was used to test ...
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miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo , by suppressing Rab1A
... proteins. miR-15b levels are reported increased in HCC tissues; however, they negatively correlate to HCC ...measure miR-15b-5p expression in both HCC tissues and HCC cell ...of ...
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miR-15b/16 protects primary human retinal microvascular endothelial cells against hyperglycemia-induced increases in tumor necrosis factor alpha and suppressor of cytokine signaling 3
... The total RNA was isolated and purified using the TRI- zol method, and the purity and quantity of RNA were measured using Nanodrop (ND-1000). For polyA tailing reverse-transcriptase PCR, 5 μg of total RNA was treated ...
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Expression of miR-15b-5p, miR-21-5p, and SMAD7 in Lung Tissue of Sulfur Mustard-exposed Individuals with Long-term Pulmonary Complications
... of miR-21-5p which can target SMAD7 transcripts and inhibit its ...of miR-15b-5p and miR-21- 5p, two regulator of TGF-β signaling pathwayand their targeted molecule, SMAD7, in lung tissue of ...
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Original Article Sevoflurane induces endoplasmic reticulum stress mediatedapoptosis inmouse hippocampal neuronal HT22 cells via modulating miR-15b-5p/Rab1A signaling pathway
... and miR-15b-5p was one of the miRNAs being most upregulated in HT22 ...of miR-15b-5p. Addition- ally, we demonstrated that miR-15b-5p suppresses Rab1A, a regulator in inducing ER ...
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Original Article MiR-15b mediates liver cancer cells proliferation through targeting BCL-2
... that miR-15b abnormal expression in the tumor and can be treated as one of the tumor molecular ...However, miR-15b expression and role in the liver cancer cells have not been ...of miR- ...
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Original Article miR-15b facilitates the progression of colorectal cancer via targeting β-catenin and Axin2
... of miR-15b on SW620 proliferation. Results showed that miR-15 mimics transfection nota- bly enhanced absorption during 24-72 h, while miR-15b inhibitor transfection did not cause marked ...
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Expression of miR-15b, miR-29b, miR-219 and miR-222 microRNAs in rats with focal cerebral ischemia submitted to physical exercise
... miRNAs: miR-21, miR-34, 28a, miR-98a, miR -148b, miR-7a and miR-15b, and others with decreased expression levels: miR-105 and miR-133b (Fernandes et ...
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Original Article miRNA-15b-5p promotes expression of osteoblast differentiation-associated markers via targeting SMAD7
... Abstract: Recent studies have recognized the involvement of microRNAs (miRNAs) in the development of osteoporosis, which regulates the balance between osteogenesis and osteoclasis. The present study was to investigate ...
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Original Article Up-regulation of microRNA-15b correlates with unfavorable prognosis and malignant progression of human glioma
... high miR-15b expression level in tumor tissues had signifi- cantly poorer overall survival and high expres- sion of miR-15b was a statistically significant risk factor of poor survival in ...
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thesis - title.pdf
... with miR-15b expression and these results were depicted in Table ...how miR-15b may not only inhibit the receptor of these processes, but also system activation as a whole because it could be ...
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The aberrant expression of microRNAs and correlations with T cell subsets in patients with immune thrombocytopenia
... of miR-146a on Th cells differentiation, PBMCs of ITP patients were cultured with or without miR-146a agomir for 4 days in condition of stimulating factors of T ...that miR-146a expression in ITP ...
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Interactions of miR 323/miR 326/miR 329 and miR 130a/miR 155/miR 210 as prognostic indicators for clinical outcome of glioblastoma patients
... Only miR-323, miR-326, miR-329, miR-130a, miR-155 and miR-210 were selected as interested candidates for further analysis; this was because, according to our knowledge, no ...
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Analysis of tissue and circulating microRNA expression during metaplastic transformation of the esophagus
... these, miR-143, miR-145, miR-194, miR-203, miR-205, miR-215 appear to have a key role in metaplasia and neoplastic ...that miR-143, miR-145, miR-194 and ...
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Aberrant plasma levels of circulating miR-16, miR-107, miR- 130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients
... of miR-107 and its down-regulation in estrogen treated MCF-7 cells ...of miR-107. Moreover, we found that inhibition of miR-107 may stimulate migration of MCF-7 cells and invasion of MCF-7 and ...
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Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method
... let-7a, mir-148a, and mir-93) that were differentially methylated or dysregulated, causing the perturbation of the MAPK and ErbB pathways, resulting in the aberrant regulation of MYC on DUSP1, EIF4E, PPIA, ...
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Original Article A three-miRNA signature as a potential biomarker for the diagnosis of glioma
... the miR-17, miR-130a, and miR-10b, with AUC of ...the miR-Score, which shows excellent diagnostic ability as compared to the 3 selected miRNAs ...that miR-17, miR- 130a, and ...
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The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loop
... of miR-329, miR-300, miR-381 and miR- 655 suppressed cell proliferation activity and cell viability in vitro and in vivo, inhibited cell motility and induced cell apoptosis in GH3 and MMQ ...
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MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1 SOCS6 , and PTEN
... the miR-21 and miR-155 expression profiles of normal human controls or cancer patients with adenocarcinoma and squamous cell carcinoma, using the parameters of overall survival (OS) and disease-free ...
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A useful method of identifying of miRNAs which can down regulate Zeb 2
... To examine the effect of microRNAs to epithelial mesen- chymal transition, we performed morphological observa- tion and fluorescent staining of filamentous actin (F-actin) in transfected cells. Normal human kidney HK-2 ...
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