miR-29
miR-29 as Indicator of Health and Disease in Sports Medicine - A Review
... that miR-29a is up- regulated in aggressive B cell chronic lymphocytic leukemia (B-CLL), and further up-regulated in indolent B-CLL, compared to non-transformed B ...expressing miR-29a/b-1 in B cells show ...
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miR-29 regulates Tet1 expression and contributes to early differentiation of mouse ESCs
... addition, miR-29a and miR-29b were also reported to function as tumor suppressors in leukogenesis ...that miR-29 may directly regulate Tet protein and is involved in cancer ...of ...
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MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging
... of miR-29 mimics ...by miR- 29 in mammals. MiR-29 decreased luciferase activity of a reporter containing mouse Ireb2 3′-UTR and repression was abrogated by mutation of three ...
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The inhibitory role of Mir-29 in growth of breast cancer cells
... cancers, MiR-29 family was reported to regulate specific genes asso- ciated with tissue invasion and metastasis in lung adeno- carcinoma ...addition, MiR-29 reduces cell growth and induces ...
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Original Article microRNA-29a repressed epithelial ovarian cancer progression by directly targeting SIRT1
... of miR-29 family, has been found up-regulated in colorectal cancer ...that miR-29a was down-regulated in human cancers, including prostate cancer [27], gastric cancer [28], esophageal carcinoma ...
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Nakamura_unc_0153D_16273.pdf
... the miR-29-deficient mice could be attributed to a number of key neuronal genes that are epigenetically hypermethylated and repressed in the absence of ...the miR-29-deficient brain, are ...
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High glucose induces renal tubular epithelial injury via Sirt1/NF kappaB/microR 29/Keap1 signal pathway
... of miR- 29 by NF-κB signal in cells and tissues [12, 13], we specu- lated that NF-κB/miR-29 axis might be involved in high glucose incubated renal ...targeting miR- 29 promotor ...
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miR-29s: a family of epi-miRNAs with therapeutic implications in hematologic malignancies
... Additionally, miR-29 family plays an important role in physiological T cell differentiation by protecting the thymus against inappropriate involution caused by infections, through down-regulation of IFNAR1 ...
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Clinical response to azacitidine therapy depends on microRNA-29c (miR-29c) expression in older acute myeloid leukemia (AML) patients
... As miR-29 targets DNA methyltransferases (DNMTs) and thus has its epigenetic effect on AML cells, we tended to verify relationship between therapy with hypomethylating agent such azacitidine and miR- ...
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Expression of miR-15b, miR-29b, miR-219 and miR-222 microRNAs in rats with focal cerebral ischemia submitted to physical exercise
... in miR-15b expression levels. The miR-29 family consists of three members (miR-29a, miR-29b and ...miR-29c). MiR-29a and miR-29b are present on chromosome 6 in mice ...
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Original Article MicroRNA-29 mediates TGFβ1-induced extracellular matrix synthesis by targeting wnt/β-catenin pathway in human orbital fibroblasts
... of miR-29 and whether miR-29 is involved in pro-survival signaling pathways mediated by TGFβ1 were examined in hu- man ...of miR-29a/b/c by real-time PCR ...of miR-29 on ...
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Original Article Suppressive role of microRNA-29 in hepatocellular carcinoma via targeting IGF2BP1
... of miR-29 have been identified in HCC, including TET1, Bcl-2 and Mcl-1 [20, ...of miR-29 may also play important roles in ...instance, miR-1275 has suppressive effects on HCC tumor ...
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Original Article MicroRNA-29 family functions as a tumor suppressor by targeting RPS15A and regulating cell cycle in hepatocellular carcinoma
... that miR-29c significantly inhibits the proliferation of squa- mous cell carcinoma cell and induces cell apoptosis ...of miR-29 family inhibits the proliferation of hepatocellular carcinoma and ...
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Interferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells
... family miR-29 with its three mature members, miR-29a, -29b and ...ively. MiR-29 family members target the expression of proteins such as methyltransferases, extracellular matrix ...
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Role of micro-RNAs in drug resistance of multiple myeloma
... (miR-15a/16-1, miR-26a, miR-29, miR-34a, and miR-150) and their role in regulation of c-MYC-mediated responses (survival, inhibition of apoptosis) have been well characterized in ...
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The roles of microRNA families in hepatic fibrosis
... fibrosis, miR‑29 family primarily induces cell apoptosis by modulating phosphatidylinositol 3‑kinase/AKT signaling pathway and regulates extracellular matrix ...accumulation. miR‑34 family promotes ...
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Changes in microRNA expression profile in hippocampus during the acquisition and extinction of cocaine-induced conditioned place preference in rats
... as miR-144, miR-451 and miR-770 in this ...as miR-129, miR-135a and miR-22 in this ...of miR-34b and miR-34c were up-regulated in CCA rats, but down-regulated in ...
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<p>Circular RNA circ_0007142 Facilitates Colorectal Cancer Progression by Modulating CDC25A Expression via miR-122-5p</p>
... To investigate the functions of circ_0007142 in CRC, si-circ _0007142 was transfected into HT-29 and HCT-116 cells. The level of circ_0007142 was distinctly declined in HT-29 and HCT-116 cells transfected ...
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<p>LINC00491 as a new molecular marker can promote the proliferation, migration and invasion of colon adenocarcinoma cells</p>
... detect miR-145 levels in HT-29, HCT116, and NCM460 ...LINC00491, miR-145 was signi fi cantly suppressed in HT-29 and HCT116 cells (Figure 3A), highlighting its inhibition in colon ...of ...
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Review Article MicroRNA-129-5p-mediated inhibition of autophagy enhanced the radiosensitivity of human colon cancer cells
... The beclin-1 3’-UTR and mutated 3’-UTR con- structs were amplified and sub cloned into pGL3 Luciferase Promote Vector (Sangon, Shanghai, China) with XbaI and NotI restriction sites. Using Lipofectamine transfection ...
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