miR-30c
hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3
... Numerous miRNAs have been implicated in tumorigen- esis, driving tumor progression, or promoting metasta- ses; however, there are still many miRNAs that have yet to be characterized with respect to these oncogenic pro- ...
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Expressions of miR-30c and let-7a are inversely correlated with HMGA2 expression in squamous cell carcinoma of the vulva
... Malignant tumors of the vulva, most of them squamous cell carcinomas, account for only 5% of cancers of the female genital tract. Though little is known about the genetic features of these tumors, the Fragile Histidine ...
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Original Article Circulating miR-665 and miR-30c-1-3p, the candidate markers of congestive heart failure with qi-deficiency-blood-stasis syndrome
... them, miR-665 and miR-30c-1- 3p draw specific ...both miR-665 and miR-30c-1-3p target on the zinc finger protein 460 and 880, which translocated into nuclear and activated GATA4 ...
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Endothelial miR 30c suppresses tumor growth via inhibition of TGF β–induced Serpine1
... of miR-30c and Serpine1 expression that defines their in vitro sprouting ...of miR-30c and Serpine1 in the TME, we used FACS to isolate TECs from 2 orthotopic tumor models or from human lung ...
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Hydrogen sulfide protects spinal cord and induces autophagy via miR-30c in a rat model of spinal cord ischemia-reperfusion injury
... the miR-30c was downregulated during spinal cord pro- tective effect of H2S in I/R ...that miR-30 could impair autophagic process by targeting multiple genes in the autophagy pathway [27] ...by ...
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<p>Expression Levels of miR-30c and miR-186 in Adult Patients with Membranous Glomerulonephritis and Focal Segmental Glomerulosclerosis</p>
... NS. MiR-30s can guard podocytes against apoptosis by targeting p53 and Notch1 and the loss of miR-30s eases podocyte ...Moreover, miR-30s stabilize the podocyte cytoskeletons by targeting some other ...
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<p>Circular RNA CircPRMT5 Accelerates Proliferation and Invasion of Papillary Thyroid Cancer Through Regulation of miR-30c/E2F3 Axis</p>
... ), miR- 30c (5 ʹ -ACCATGCTGTAGTGTGTGTAAACA-3 ʹ and 5 ʹ - TCCATGGCAGAAGGAGTAAA-3 ʹ ), E2F3 (5 ʹ -TGACCC AAT GGTAGGCACAT-3 ʹ and 5 ʹ -CATCTAGGACCACAC CGACA-3 ʹ ) and GAPDH (5 ʹ -TGCACCACCAACTGCTT AGC-3 ʹ and ...
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Expression of microRNA-30c via lentivirus vector inhibits the proliferation and enhances the sensitivity of highly aggressive ccRCC Caki-1 cells to anticancer agents
... of miR-30c in metastatic ccRCC by targeting ...via miR-30c significantly attenuated the proliferation or anchorage-independent growth of Caki-1 ...of miR-30c disrupted the ...
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PubMedCentral-PMC5000085.pdf
... of miR-30c mimic in female WT mice that were fed a Western diet for 4 weeks ...of miR-30c effects. After a single injection of 5 mg/kg/ week miR-30c mimic, significant reductions ...
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Supplementary site interactions are critical for the regulation of microsomal triglyceride transfer protein by microRNA-30c
... These studies clearly show that supplementary interac- tions play a role in determining specificity and enhan- cing binding between miR-30c and MTTP. Previously, the importance of the interactions at the ...
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Early and Short-term Triiodothyronine Supplementation Prevents Adverse Postischemic Cardiac Remodeling: Role of Transforming Growth Factor-β1 and Antifibrotic miRNA Signaling
... of miR-133a, miR-30c and miR-29c, we next assessed its effect on validated targets of these miRNAs, such as CTGF and MMP-2 at the 3- and 14-d ...
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miRNAs Expression and Role of Dicer on Podocyte Injury in PAN Nephrosis Rats
... Objective: microRNAs (miRNAs) are regulatory RNAs that act as important players in diverse bi- ologic and pathologic processes. Under circumstance as podocye-injury triggering proteinuria, which miRNAs are up-regulated ...
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miRNA-30c can be used as a target in the diagnosis and treatment of osteosarcoma
... of miR-30c on osteosarcoma and its potential ...of miR-30c was significantly high in the normal bone tissue than in osteosarcoma ...of miR-30c was associated with more invasive ...
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Collagen triple helix repeat containing-1 negatively regulated by microRNA-30c promotes cell proliferation and metastasis and indicates poor prognosis in breast cancer
... Last but not least, in this study we identified CTHRC1 as an independent prognostic factor for breast cancer patients, suggesting it might be used for molecular clas- sification of breast cancer. Precision medicine is ...
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Multiple microRNAs regulate human FOXP2 gene expression by targeting sequences in its 3' untranslated region
... that miR-9, miR-132, and miR-140-5p regu- late Foxp2/FoxP2 expression (Foxp2 and FoxP2 denote re- spective rodent and avian genes) in animal models [21,22], highlight the importance of the FOXP2 3′ ...
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Review Article Dysregulated microRNAs with prognostic significance in human hepatocellular carcinoma: a study based on high-throughput microarray
... of miR-199a-3p in HCC tissues was ...that miR-199a-3p could be a novel serum diagnostic biomarker for HCC ...low miR-199a-3p expression was related with the poor prognosis in HCC [55, 91, ...low ...
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Advance in microRNA as a potential biomarker for early detection of pancreatic cancer
... by miR-96, miR-126, miR-143/145, miR-217 and Let-7 ...of miR-34 family (miR-34a/b/c). miRNAs such as miR-21, miR-143, miR-155, miR-130a/301a/454, ...
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Aberrant plasma levels of circulating miR-16, miR-107, miR- 130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients
... that miR-107 is associated with ER-negative breast cancer, we examined whether ER is a target of ...the miR databases DIANA-microT-CDS [23], ...of miR-107 in the 3’UTR of ER (Supplementary Figure ...
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MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1 SOCS6 , and PTEN
... with miR-21 and miR-155 antisense sequences induced the apoptosis of A549 and H1299 cells (Figure ...with miR-21, miR-155, or miR-21/155 antagomirs (Figure ...with miR-21, ...
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Expression profiling and bioinformatic analyses suggest new target genes and pathways for human hair follicle related microRNAs
... of miR-137, miR-214 and miR-410 in the human HF. While miR-137 has been described in the determination of murine coat colour [5], no data are available concern- ing the expression pattern of ...
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