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Mitochondrial electron transport chain

Evaluation of functioning of mitochondrial electron transport chain with NADH and FAD autofluorescence

Evaluation of functioning of mitochondrial electron transport chain with NADH and FAD autofluorescence

... M itochondria are the key players of cell ener gy metabolism, programmed cell death and oxidative stress. Polarogra- phy with Clark electrode is a widely used method for evaluation of functional activity of mitochondria ...

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Variation among Plasmodium falciparum Strains in Their Reliance on Mitochondrial Electron Transport Chain Function

Variation among Plasmodium falciparum Strains in Their Reliance on Mitochondrial Electron Transport Chain Function

... the mitochondrial electron transport chain (mtETC) inhibitor atovaquone when the mtETC was decoupled from the pyrimidine biosynthesis pathway by expressing the fumarate-dependent ...

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Mitochondrial dysfunction in Autism Spectrum Disorders

Mitochondrial dysfunction in Autism Spectrum Disorders

... between mitochondrial dysfunction and autism, it does not provide the prospective insight that in vivo investigation could ...of mitochondrial function in vivo by measuring optical changes in the brain ...

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Dissecting cellular senescence and SASP in Drosophila

Dissecting cellular senescence and SASP in Drosophila

... the mitochondrial electron transport chain (Ras V12 /mito −/− clones), both of which are frequently ob- served in various types of human cancers [44–48], show elevated SA-β-gal activity, cell ...

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Molecular and biochemical characterisation of the electron transport chain of plasmodium falciparum

Molecular and biochemical characterisation of the electron transport chain of plasmodium falciparum

... a mitochondrial integrity is required for different functions such as [Fe-S] cluster assembly and heme and pyrimidine biosynthesis, which have become attractive targets for antimalarial drugs (Bonday et ...

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Increased ATP generation in the host cell is required for efficient vaccinia virus production

Increased ATP generation in the host cell is required for efficient vaccinia virus production

... encoding mitochondrial electron transport chain proteins after VV infection Both ND4 and COII are mitochondrial genes whose pro- tein products are part of the electron ...

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Mitocans as Novel Agents for Anticancer Therapy: An Overview

Mitocans as Novel Agents for Anticancer Therapy: An Overview

... the mitochondrial membrane for ATP ...an electron escapes from the electron transport chain in mitochondria especially at complex I or III, it may react with molecular oxygen to form ...

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Relationships between expression of BCS1L, mitochondrial bioenergetics, and fatigue among patients with prostate cancer

<p>Relationships between expression of BCS1L, mitochondrial bioenergetics, and fatigue among patients with prostate cancer</p>

... between mitochondrial gene expression, mito- chondrial oxidative phosphorylation (OXPHOS), electron transport chain ETC complex (ETC) activity, and fatigue symptoms in prostate cancer patients ...

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Aged rat heart: Modulation of age related respiratory defects decreases ischemic reflow injury

Aged rat heart: Modulation of age related respiratory defects decreases ischemic reflow injury

... the electron transport chain that is superimposed upon age-related ...in electron transport chain com- plexes III and IV was corrected in the ...tron transport are a key ...

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2, 4-Diamino-6- hydroxy pyrimidine inhibits NSAIDs induced nitrosyl-complex EPR signals and ulcer in rat jejunum

2, 4-Diamino-6- hydroxy pyrimidine inhibits NSAIDs induced nitrosyl-complex EPR signals and ulcer in rat jejunum

... of electron transport occurs with all commonly available acidic- ...uncouple mitochondrial oxi- dative phosphorylation at concentration between 30 and 500 µ M and inhibit the electron ...

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Common aging pathways in worms, flies, mice and humans

Common aging pathways in worms, flies, mice and humans

... the electron transport pathway, was observed in worms, flies, mice and humans (Zahn et ...the electron transport chain in old age are not ...because mitochondrial function is ...

6

Age related changes in H2O2 production and bioenergetics in rat brain synaptosomes

Age related changes in H2O2 production and bioenergetics in rat brain synaptosomes

... reduced electron fl ow through the electron transport chain, a reduction in proton pumping out of the mitochondrial matrix would be expected, resulting in a lower level of Δψ m ...

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Dual Mutations Reveal Interactions Between Components of Oxidative Phosphorylation in Kluyveromyces lactis

Dual Mutations Reveal Interactions Between Components of Oxidative Phosphorylation in Kluyveromyces lactis

... of diploid strains heterozygous for disruptions in genes for the two components of oxidative phosphoryla- tion results in the formation of nonviable spores inferred to contain both disruptions. Lethality of spores is ...

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EFFECT OF ENDOSULPHAN ON LACTIC DEHYDROGENASE ACTIVITIES IN THE VITAL TISSUES OF SWISS ALBINO MICE

EFFECT OF ENDOSULPHAN ON LACTIC DEHYDROGENASE ACTIVITIES IN THE VITAL TISSUES OF SWISS ALBINO MICE

... of mitochondrial respiration was found to occur in parallel to the inhibition of enzyme activities of the respiratory electron transport chain of mitochondria such as LDH thus the result of ...

5

Ischemia time impacts on respiratory chain functions and Ca2+-handling of cardiac subsarcolemmal mitochondria subjected to ischemia reperfusion injury

Ischemia time impacts on respiratory chain functions and Ca2+-handling of cardiac subsarcolemmal mitochondria subjected to ischemia reperfusion injury

... overall mitochondrial function and integritiy [8, 9], we hypothesized that iso- lated SSM might be particularly affected in a time dependent manner by increasing intervals of ischemia during ...homeostasis, ...

8

Cycling Exercise Training Enhances Mitochondrial Bioenergetics of Platelets in Patients with Peripheral Arterial Disease: A Randomized Controlled Trial

Cycling Exercise Training Enhances Mitochondrial Bioenergetics of Platelets in Patients with Peripheral Arterial Disease: A Randomized Controlled Trial

... Before the graded exercise test at the beginning of the present study and 12 weeks later in various groups, 20 ml of blood was sampled from each subject's antecubital vein within 1 min by venipuncture (20-gauge needle). ...

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An investigation into the effects of magnetic fields on biological cell processes

An investigation into the effects of magnetic fields on biological cell processes

... field Electron paramagnetic resonance Extracellular-signal-regulated kinase Electron transport chain Fetal bovine serum Finite element method Glutathione Glutathione peroxidase High cont[r] ...

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Biochemical Changes in Mitochondria and its Role in Cell Death During Myocardial Ischemia-Reperfusion Injury.

Biochemical Changes in Mitochondria and its Role in Cell Death During Myocardial Ischemia-Reperfusion Injury.

... reduced electron flow through complex IV both in permeabilized ischemic tissue and mitochondria isolated from ischemic heart ...mediates electron transfer between complexes III and IV, from the ...

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Rapid ecotoxicological tests using bioassay systems - a review

Rapid ecotoxicological tests using bioassay systems - a review

... The reduction of luminescence occurs when the luciferase enzyme and several related enzymes (e.g. electron transport chain) are inhibited which interferes with the [r] ...

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Regulation of ethanol metabolism in isolated rat hepatocytes : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University

Regulation of ethanol metabolism in isolated rat hepatocytes : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University

... To detennine the importance of the shuttle systems and electron transport chain in the regulation of ethanol metabolism, the flux control coefficients of the individual enzymes.. partici[r] ...

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