mitochondrial tRNA
Mutational Analysis of Mitochondrial tRNA Genes in Patients with Asthma
... the mitochondrial tRNA genes and subsequently sequenced the PCR products, and we used the pathogenicity scoring system to evaluate the potential role of these ...
6
Polymorphism of mitochondrial tRNA genes associated with the number of pigs born alive
... the tRNA-Phe, tRNA-Val, tRNA-Ala, tRNA-Cys, tRNA-Gly, tRNA-Leu(UAG), tRNA-Glu, and tRNA-Thr genes, ...several mitochondrial tRNA point mutations in- ...
10
Original Article Mitochondrial tRNA Glu A14683G may be a novel mutation associated with inherited hypertension
... in mitochondrial tRNA ...the mitochondrial dysfunction that was re- sponsible for ...the mitochondrial A14683G mutation should be regarded as a risk factor for ...
6
The point mutations of mitochondrial tRNA threonine and proline in idiopathic repeated pregnancy loss
... of tRNA Pro ...including tRNA mutations are ...The mitochondrial genome is extremely susceptible to damages from continuous exposure to ...from mitochondrial respiratory chain and have been ...
6
Mutation Analysis of the Mitochondrial tRNA Genes in Iranian Coronary Atherosclerosis Patients
... ten mitochondrial tRNA genes (about 50%) were investigated in 70 patients from October 2013 and June 2015 suffered from ...related mitochondrial area was am- plified using PCR ...
7
Original Article Analysis of mitochondrial tRNA Thr variants in patients with essential hypertension
... complete mitochondrial DNA (mtDNA) genes showed the presence of ND1 T3394C and G15927A mutations, as well as a set of polymorphisms belonging to human mito- chondrial haplogroup ...
8
Mitochondrial DNA T7719G in tRNA-Lys gene affects litter size in Small-tailed Han sheep
... with mitochondrial tRNA-Asp A7551G mutation [27], hypertension was associated with mitochondrial tRNA- Ile A4263G mutation [28], and mitochondrial tRNA mu- tations might decrease ...
6
Post-transcriptional Modifications of the tRNA Anticodon Stem and Loop (ASL) Affect the Ability of tRNA to Bind Synonymous Codons.
... elongator tRNA Met ) are universal among prokaryotic and eukaryotic, cytoplasmic translational ...one tRNA Met species that reads both codons at both the P- and A-sites of the ribosome (Young and Anderson ...
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Two novel pathogenic mitochondrial DNA mutations affecting organelle number and protein synthesis Is the tRNA(Leu(UUR)) gene an etiologic hot spot?
... different mitochondrial tRNA genes: the first mutation in the tRNA(Asn) gene, and the ninth known mutation in the tRNA(Leu(UUR)) ...in tRNA(Asn) was associated with isolated ...
11
Mitochondrial aminoacyl-tRNA synthetase disorders: an emerging group of developmental disorders of myelination
... encodes mitochondrial aspartyl-tRNA synthe- tase (mtAspRS), the enzyme that attaches aspartate to the correct mitochondrial ...of mitochondrial mRNA into functional ...
15
Research on the Repeated Sequences among tRNA Sequences
... sequences. As it is shown by Figure 2, the abscissa denotes the repeated sequence i, and the ordinate denotes the probability P(i) of i. Taking into account the paper’s space, therefore we only insert two diagrams into ...
7
On origin of genetic code and tRNA before translation
... of tRNA recognition by putative r-aaRSs for complementa- rily encoded amino acids ...of tRNA aminoacyla- tion embodied mostly in the acceptor stem [25,26] and the classic code associated with anticodons by ...
24
Prediction and verification of mouse tRNA gene families
... two tRNA scanning programs, the commonly used tRNAscan-SE and more recently developed ARAGORN, to predict the probable tRNA genes in the mouse ...definitive tRNA gene identification program. Initial ...
16
A human leucyl-tRNA synthetase as an anticancer target
... is often misregulated in human cancers, and the gene plays a role as a tumor suppressor or as an oncogene, depending on the cellular context and circumstances. On the other hand, as CHX inhibits protein synthesis by ...
10
A MUTANT OF YEAST WITH A DEFECTIVE METHIONYL-tRNA SYNTHETASE
... In forty-five of the forty-seven tetrads from hybrid HI9 le- : le+ segregated 2 : 2 and the ts- 296 mutation (methionyl-tRNA synthetase) displayed a second division segr[r] ...
10
FRAMESHIFT SUPPRESSION IN AMINOACYL-tRNA LIMITED CELLS
... We might add that our experiments focus on increases in ribosome frame- shifting brought about by aminoacyl-tRNA limitation, and therefore probably pertain to transl[r] ...
13
Evaluation of tRNA Gene PCR for Identification of Mollicutes
... Identification of strains. Most strains (i.e., MYP10 to MYP58 and MYP65 to MYP74) had been identified previously by means of phenotypical characteristics and the growth precipitation test using absorbed rabbit antisera ...
9
Reaction of anti OJ autoantibodies with components of the multi enzyme complex of aminoacyl tRNA synthetases in addition to isoleucyl tRNA synthetase
... believed to be glutaminyl-tRNA synthetase. Despite reaction of some sera with additional synthetases, the immunoprecipitated tRNA appeared the same with all sera, and functioned as tRNA(ile). While ...
10
Viral Hijacking of Mitochondrial Lysyl-tRNA Synthetase
... and mitochondrial species with similar ...the mitochondrial (mito- LysRS) enzymes ...characteristic mitochondrial pattern is ob- ...terized mitochondrial targeting sequence from subunit VIII ...
6
Investigating tRNA Release from the Bacterial Ribosome
... is tRNA. In bacterial cells there are about 40 tRNA molecules, each composed of about 76 ...the tRNA via an esterification utilizing amino acid-specific tRNA-synthetases and ATP (Figure ...
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