Mitogen-Activated Protein Kinase 3
Kinase Activity Profiling of Gram-Negative Pneumonia
... approach. Kinase activity arrays enable the analysis of 1,024 con- sensus sequences of protein kinase ...a kinase activity array on whole lung lysates, cellular kinase activities were ...
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Leptin signaling molecular actions and drug target in hepatocellular carcinoma
... (phosphoinositide 3-kinase [PI-3K]/protein kinase B [Akt], mitogen-activated protein kinase [MAPK]/extracellular regulated kinase 1 and 2 [ERK 1/2]), and ...
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Stem cells and the impact of ROS signaling
... AKT, protein kinase B; AMPK, 5 ′ adenosine monophosphate-activated protein kinase; BMI1, Bmi1 polycomb ring finger oncogene; F6P, fructose 6-phosphate; F1,6P, fructose 1,6-bisphosphate; ...
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PKM2, function and expression and regulation
... mitogen activated protein kinase; MAPKK5/MEK5: mitogen activated protein kinase kinase 5; MG: methylglyoxal; MLC2: myosin light chain 2; MiR/miRNA: microRNA; ...
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Flavonoids in modulation of cell survival signalling pathways
... phosphoinositide 3-kinase, Akt/protein kinase B, mitogen-activated protein kinase, tyrosine kina- ses, and protein kinase ...
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Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5)
... In order to evaluate the models’ ability to distinguish between real inhibitors and decoy substances, the three different models were docked both with the 90 decoy ligands and 10 inhibitors in a semi-flexible mode. Score ...
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Mitogen-activated protein kinase phosphatase-3 (MKP-3) in the surgical wound is necessary for the resolution of postoperative pain in mice
... Abstract: Mitogen-activated protein kinase (MAPK) phosphatase-3 (MKP-3) and its substrates (extracellular signal-regulated kinase [ERK] and p38) play an important role in ...
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A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases
... the kinase under investigation. The protein kinases of the mammalian genome can be divided into several groups ...the mitogen-activated protein kinases (MAPKs) are strongly implicated ...
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Modulation of Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 by Hepatitis C Virus Core Protein
... panel). Protein expressions of MAPKAPK3, MAPKAPK3-KA, core, and actin were verified using the same cell lysates with the indicated antibodies (left, lower ...deviations. Protein expressions of core, ...
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“Docking Studies on Eupalitin-3-O-β-D-galactopyranoside as Potential Inhibitor of Cyprinus carpio (KOI CARP) MAPK/ERK Kinase 2 and Mitogen-Activated Protein Kinase (p38)” by Kader Asen Fathima, Chetancherry Somasundaram Parameswari, India.
... a protein kinase that participates in the RAS-RAF-MEK-ERK signal transduction cascade in the regulation of a large variety of processes including apoptosis, cell cycle progression, cell migration, ...
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Regulation of Sox9 activity by crosstalk with nuclear factor κB and retinoic acid receptors
... RARE 3 -luc), regu- lated by activation of RARs via retinoic acid [28]; and a type II collagen enhancer luciferase reporter containing four repeats of the 48-bp minimal enhancer of the type II collagen gene (pGL3 ...
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Enhanced expression of microtubule-associated protein 7 functioned as a contributor to cervical cancer cell migration and is predictive of adverse prognosis
... Active‑caspase 3 and Bax, but declined the level of ...of mitogen‑activated protein kinase kinase (MEK) and extracellular signal‑regulated kinase (ERK) in Caski and HeLa ...
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Mitogen-Activated Protein Kinase Pathways and Fungal Pathogenesis
... scaffold protein Ste5 and a p21- activated protein (PAK) kinase, Ste20, and is essential for the activation of the Ste11-Ste7–Fus3/Kss1 ...dependent kinase inhibitor Far1 and the Ste12 ...
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Supplementing L-isoleucine increases medium protein and alters the expression of genes and proteins involved in milk protein synthesis and energy metabolism in bovine mammary cells
... milk protein synthesis, using an immortalized bovine mammary epithelial (MAC-T) cell ...for protein synthesis for each amino acid was determined by measuring the cell, medium and total protein at 0, ...
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Mitogen-Activated Protein Kinase Kinase 2, a Novel E2-Interacting Protein, Promotes the Growth of Classical Swine Fever Virus via Attenuation of the JAK-STAT Signaling Pathway
... viral protein FIG 7 Inhibition of the interferon-induced JAK-STAT signaling pathway abolishes the increase of CSFV replication by the MEK2/ERK1/2 ...Viral protein expression in the U0126- and Ruxo-treated ...
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Hyperexpression of mitogen activated protein kinase in human breast cancer
... MAP kinase activity and expression were stained with hema- toxylin and eosin ...(Fig. 3 A ); representative cancer cells are highlighted by ...(Fig. 3 B ...MAP kinase demonstrates nuclear ...
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A role for mitogen-activated protein kinase in epidermal hyperproliferation and inflammation
... Keratinocyte isolation from mouse neonates was perform ed according to (Roper et al., 2001). Newborn mice (2-4 days old) were killed and placed on ice for at least 1 hour. The mice were then washed sequentially with 10 % ...
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Regulation of the mitogen activated protein kinase p44 ERK activity during anoxia/recovery in rainbow trout hypodermal fibroblasts
... inactive kinase to the nuclear compartment (Mizukami and Yoshida, ...was activated in response to reperfusion, suggesting an interface capable of ERK activation in the nuclear ...inositol ...
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From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis
... signal-regulating kinase 1; AP-1-Jun: Activator protein-1-JUN; ATP: Adenosine triphosphate; BCG: Bacillus Calmette-Guerin; Bcl-2: B-cell lymphoma 2; CARD15: Caspase associated recruitment domain 15; CD4+: ...
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Emerging treatment options to improve cardiovascular outcomes in patients with acute coronary syndrome: focus on losmapimod
... under the curve [AUC] for troponin I within 72 hours or by discharge, whichever was first). Secondary efficacy measures were hsCRP level at week 14 and IL-6 level at 24 hours and week 12, in addition to Creatine ...
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