Mitogen-Activated Protein Kinases
Activation of mitogen-activated protein kinases by a splice variant of GHRH receptor
... in vitro and the expression of proliferative cell nuclear antigen. We also demonstrated that when the cells transfected with SV1 plasmid are stimulated with GHRH (1–29)NH 2 , SV1 receptor activates the ...
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Mitogen-activated protein kinases and mitogen kinase phosphatase 1: a critical interplay in macrophage biology
... the mitogen-activated protein kinases (MAPKs) and mitogen kinase phosphatase-1 (MKP-1) in the functional activities of ...these kinases, thus playing a balancing role in the ...
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Mitogen-activated protein kinases in normal and (pre)neoplastic ovarian surface epithelium
... Abstract Mitogen-activated protein kinases (MAPKs) are a group of serine/threonine kinases which are activated in response to a diverse array of extracellular stimuli and mediate ...
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A3 adenosine receptors and mitogen activated protein kinases in lung injury following in vivo reperfusion
... terminal protein kinases; LLL = left lower lobe; MAPK = mitogen activated protein kinases; MPO = myeloperoxidase; PI = propidium iodide; ...
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Mitogen-Activated Protein Kinases Regulate LSF Occupancy at the Human Immunodeficiency Virus Type 1 Promoter
... Veterans Health Care Systems, Dallas, Texas 75216 3 Received 30 November 2004/Accepted 3 January 2005 Human immunodeficiency virus type 1 (HIV-1) establishes a persistent, nonproductive state within a small population of ...
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The Involvement of Mitogen-Activated Protein Kinases in the 1,25-Dihydroxy-Cholecalciferol-Induced Inhibition of Adipocyte Differentiation In Vitro
... cells, mitogen-activated protein kinases Obesity is an important disease in the realm of pre- ventive medicine because it is regarded as a risk factor for a broad spectrum of cardiometabolic ...
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Guibitang, a traditional herbal medicine, induces apoptotic death in A431 cells by regulating the activities of mitogen activated protein kinases
... of mitogen-activated protein kinases (MAPKs) including extracellular signal-regulated kinase (ERK), p38 and c-Jun NH2-terminal kinase (JNK), and activated p53, a tumor suppressor ...
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Original Article Activation profile of intracellular mitogen-activated protein kinases in CD8+ T lymphocytes of patients with severe aplastic anemia
... by activated T lymphocytes. Mitogen-activated protein kinases (MAPKs) are serine and threonine protein kinases that can be activated by phosphorylation in response ...
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Acute hypertension activates mitogen activated protein kinases in arterial wall
... MAP kinases • ERK/JNK • transcription factors • artery remodeling Introduction Many factors ranging from physical exertion to psychological stress lead to neuroendocrine responses including release of ...
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Role of Trichoderma reesei mitogen-activated protein kinases (MAPKs) in cellulase formation
... Mitogen-activated protein kinase pathways are the best characterized signal transduction pathways in eukary- otes. Although the functions of many MAPK pathways are conserved in fungi, they also play ...
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Clinicopathological and prognostic significance of mitogen activated protein kinases (MAPK) in breast cancers
... are activated in response to aberrant oncogenic stimulation and remarkably induce growth inhibition that is referred to as oncogenic-induced senescence [51, ...death-associated protein kinase could ...
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Cyclic nucleotides and mitogen-activated protein kinases: regulation of simvastatin in platelet activation
... DAG [16]. DAG activates PKC, inducing protein phos- phorylation (p47). PKC activation represents a strategy adopted by cells to allow selected responses to specific activating signals in distinct cellular ...
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Nucleoporin Phosphorylation Triggered by the Encephalomyocarditis Virus Leader Protein Is Mediated by Mitogen-Activated Protein Kinases
... Our L 4D/4A vEC 9 mutations disrupt this putative site, perhaps accounting for the inactive phenotype. Unfortunately, the specificity of PP2A for its substrates is not readily defined by sequence, because the enzyme uses ...
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Mitogen-activated protein kinases and NFκB are involved in SP-A-enhanced responses of macrophages to mycobacteria
... Total protein was extracted as described above. Activated ERK-1/2 was immunoprecipitated using a phospho-specific ...fusion protein and allowed to incubate for 5 ...equal protein loading by ...
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Mitogen activated protein kinases SakA(HOG1) and MpkC collaborate for Aspergillus fumigatus virulence
... the protein concentrations were determined using the Bradford method (Bradford, 1976) ...of protein from each sample were resolved in a 12% (w/v) SDS–PAGE and transferred to polyvinylidene diflu- oride ...
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Mitogen activated protein kinases: new signaling pathways functioning in cellular responses to environmental stress
... novel protein kinases that interfered with mating phermone-induced growth arrest and mating-induced cell fusion (Courchesne et ...the mitogen-activated protein kinase (MAPK) superfamily ...
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ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially
... these kinases might interfere with growth of transformed cells, by examining the growth of double transfectants containing oncogenic Ras and one of the wild-type or mutant kinases described ...
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Role of mitogen-activated protein kinases in myocardial ischemia-reperfusion injury during heart transplantation
... Abstract: In solid organ transplantation, ischemia/reperfusion (IR) injury during organ procurement, storage and reperfusion is an unavoidable detrimental event for the graft, as it amplifies graft inflamma- tion and ...
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Tumour necrosis factor activates the mitogen activated protein kinases p38α and ERK in the synovial membrane in vivo
... Despite the potential of TNF to activate all three MAPKs, the pathways that are of relevance to chronic destructive arthritis remain to be elucidated. However, if we are to design thera- peutic tools that can effectively ...
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Sustained Activation of Mitogen-Activated Protein Kinases and Activator Protein 1 by the Hepatitis B Virus X Protein in Mouse Hepatocytes In Vivo
... Although our study suggests a potential role of HBx-induced signaling cascades in carcinogenesis, it does not preclude the involvement of additional mechanisms in such a process. It might be speculated that HBx behaves ...
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