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mitogen-activated protein (MAP) kinase

Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF κB and mitogen activated protein kinase pathways

Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF κB and mitogen activated protein kinase pathways

... selective mitogen-activated protein/ERK kinase (MEK) inhibitor), and SB203580 (a selective p38 MAP kinase inhibitor) were ap- plied to verify the contribution of p38 MAP ...

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Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5)

Homology modeling and ligand docking of Mitogen-activated protein kinase-activated protein kinase 5 (MK5)

... on mitogen-activated protein kinase-activated protein kinase 5 ...MK5 protein is a highly conserved protein kinase within vertebrates sharing 87 to ...

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Regulation of the mitogen activated protein kinase p44 ERK activity during anoxia/recovery in rainbow trout hypodermal fibroblasts

Regulation of the mitogen activated protein kinase p44 ERK activity during anoxia/recovery in rainbow trout hypodermal fibroblasts

... inactive kinase to the nuclear compartment (Mizukami and Yoshida, ...was activated in response to reperfusion, suggesting an interface capable of ERK activation in the nuclear ...3- kinase) and the ...

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Role of Rho GTPases and PTEN in the migration of human glioma cells

Role of Rho GTPases and PTEN in the migration of human glioma cells

... Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways, J Cell Biol 143,1375-83. Proliferation[r] ...

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Selective activation of the mitogen activated protein kinase subgroups c Jun NH2 terminal kinase and p38 by IL 1 and TNF in human articular chondrocytes

Selective activation of the mitogen activated protein kinase subgroups c Jun NH2 terminal kinase and p38 by IL 1 and TNF in human articular chondrocytes

... that protein ty- rosine kinase activation was required for the expression of a broad spectrum of IL-1 inducible genes in human articular chondrocytes (30, ...as MAP ki- nases ERK-1 and ...

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Mitogen-Activated Protein Kinase Pathways and Fungal Pathogenesis

Mitogen-Activated Protein Kinase Pathways and Fungal Pathogenesis

... are activated by Slt2 to regulate cell wall syn- thesis and cell cycle (52, ...be activated by two upstream ...dine kinase phospho-relay system comprised of Sln1, Ypd1, and ...MAPK activated ...

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Role of the stress activated protein kinases in endothelin induced cardiomyocyte hypertrophy

Role of the stress activated protein kinases in endothelin induced cardiomyocyte hypertrophy

... stress-activated protein ki- nase (SAPK) family of mitogen-activated protein (MAP) ki- nases or another stress-response MAP kinase, p38, by over- expression of ...

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Modulation of Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 by Hepatitis C Virus Core Protein

Modulation of Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 by Hepatitis C Virus Core Protein

... deviations. Protein expressions of MAPKAPK3, MAPKAPK3-SR, core, and actin were verified using the same cell lysates with the indicated antibodies (lower ...significant. Protein expressions of MAPKAPK3-WT, ...

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MAP2K6 is associated with radiation resistance and adverse prognosis for locally advanced nasopharyngeal carcinoma patients

MAP2K6 is associated with radiation resistance and adverse prognosis for locally advanced nasopharyngeal carcinoma patients

... are protein kinases, and there are > 500 kinases in the mammalian ...genome. Protein kinases, such as receptor tyrosine kinases, cyclin- dependent kinases, and MAP kinases (MAPKs) accounts for the ...

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Supplementing L-isoleucine increases medium protein and alters the expression of genes and proteins involved in milk protein synthesis and energy metabolism in bovine mammary cells

Supplementing L-isoleucine increases medium protein and alters the expression of genes and proteins involved in milk protein synthesis and energy metabolism in bovine mammary cells

... milk protein synthesis, using an immortalized bovine mammary epithelial (MAC-T) cell ...for protein synthesis for each amino acid was determined by measuring the cell, medium and total protein at 0, ...

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From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis

From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis

... signal-regulating kinase 1; AP-1-Jun: Activator protein-1-JUN; ATP: Adenosine triphosphate; BCG: Bacillus Calmette-Guerin; Bcl-2: B-cell lymphoma 2; CARD15: Caspase associated recruitment domain 15; CD4+: ...

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Enhanced expression of microtubule-associated protein 7 functioned as a contributor to cervical cancer cell migration and is predictive of adverse prognosis

Enhanced expression of microtubule-associated protein 7 functioned as a contributor to cervical cancer cell migration and is predictive of adverse prognosis

... of mitogenactivated protein kinase kinase (MEK) and extracellular signal‑regulated kinase (ERK) in Caski and HeLa cells, and overexpression of MAP7 increased their ...

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Original Article Association detection between genetic variants in the microRNA binding sites of toll-like receptors signaling pathway genes and bladder cancer susceptibility

Original Article Association detection between genetic variants in the microRNA binding sites of toll-like receptors signaling pathway genes and bladder cancer susceptibility

... TLRs signaling pathway genes polymorphisms and bladder cancer risk mitogen-activated protein kinase 1 protein kinase C, beta 1 protein kinase C, alpha protein kinase, cAMP-dependent, reg[r] ...

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MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts

MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts

... G protein- coupled signaling pathways including mitogen-activated protein kinase (MAPK), which subsequently induce sev- eral cellular responses including gene expression and pulmonary ...

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Regulation of Sox9 activity by crosstalk with nuclear factor κB and retinoic acid receptors

Regulation of Sox9 activity by crosstalk with nuclear factor κB and retinoic acid receptors

... active mitogen-activated protein kinase kinase kinase (caMEKK)1 (Clontech, Mountain View, CA, USA), a phosphorylation site- deficient IκB (IκB-2N; pSVK3-IκB-2NΔ4) [30], or ...

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PKM2, function and expression and regulation

PKM2, function and expression and regulation

... mitogen activated protein kinase; MAPKK5/MEK5: mitogen activated protein kinase kinase 5; MG: methylglyoxal; MLC2: myosin light chain 2; MiR/miRNA: microRNA; ...

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Kinase Activity Profiling of Gram-Negative Pneumonia

Kinase Activity Profiling of Gram-Negative Pneumonia

... by protein kinases and phos- phatases, regulates signal transduction pathways ...a kinase activity array with 1,024 consensus sequences to reveal sequential processes during the course of ...p38 ...

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Flavonoids in modulation of cell survival signalling pathways

Flavonoids in modulation of cell survival signalling pathways

... on protein kinase and lipid kinase signalling ...phosphatidylinositol-3 kinase (PI3K) (Choi 2011; Kyoung et al. 2010; Lin et al. 2012), protein kinase B (Akt/PKB) (Hwang and Yen ...

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Molecular responses to abiotic stress and the development of drought tolerance in plants

Molecular responses to abiotic stress and the development of drought tolerance in plants

... A gene encoding a mitogenactivated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, c[r] ...

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Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein.

Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein.

... The PKCl gene product, protein kinase C, regulates a mitogen-activated protein kinase (MAPK) cascade, which is implicated in cell wall metabolism.. Previously, we i[r] ...

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